Browse our anti-SOCS2 (SOCS2) Antibodies

Full name:
anti-Suppressor of Cytokine Signaling 2 Antibodies (SOCS2)
On are 53 Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies from 20 different suppliers available. Additionally we are shipping SOCS2 Kits (14) and SOCS2 Proteins (11) and many more products for this protein. A total of 83 SOCS2 products are currently listed.
8030460M17, AI527257, AW108012, CIS2, Cish2, D130043N08Rik, hg, JAB, si:dkey-202b22.1, Socs-2, socs2, SSI-2, SSI2, STATI2
list all antibodies Gene Name GeneID UniProt
SOCS2 8835 O14508
SOCS2 216233 O35717
SOCS2 84607 O88582

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Top referenced anti-SOCS2 Antibodies

  1. Human Polyclonal SOCS2 Primary Antibody for ELISA, WB - ABIN269520 : Ransome, Turnley: Analysis of neuronal subpopulations in mice over-expressing suppressor of cytokine signaling-2. in Neuroscience 2005 (PubMed)
    Show all 8 references for 269520

  2. Human Polyclonal SOCS2 Primary Antibody for ELISA, WB - ABIN563827 : Hamilton, Lin, Wang, Knowlton: Effect of ovariectomy on cardiac gene expression: inflammation and changes in SOCS gene expression. in Physiological genomics 2008 (PubMed)

More Antibodies against SOCS2 Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Suppressor of Cytokine Signaling 2 (SOCS2) interaction partners

  1. The upregulation of SOCS-1 (show SOCS1 Antibodies) and SOCS-2 by cortisol may be playing a key role in suppressing cytokine signaling and the associated inflammatory response.

Human Suppressor of Cytokine Signaling 2 (SOCS2) interaction partners

  1. Targeting of SOCS2 by miR (show MLXIP Antibodies)-194 resulted in derepression of the oncogenic kinases FLT3 (show FLT3 Antibodies) and JAK2 (show JAK2 Antibodies), leading to enhanced ERK (show EPHB2 Antibodies) and STAT3 (show STAT3 Antibodies) signaling.

  2. Single-cell RNA sequencing reveals enrichment of homeostatic modules in monocytes and dendritic cells from human metastatic melanoma. Suppressor-of-cytokine-2 (SOCS2) protein, a conserved program transcript, is expressed by mononuclear phagocytes infiltrating primary melanoma and is induced by IFNgamma.

  3. this study shows that IL-7 (show IL7 Antibodies) induces the expression of SOCS2 through the JAK (show JAK3 Antibodies)/STAT-5 (show STAT5A Antibodies) pathway and that SOCS2 interacts with CD127 (show IL7R Antibodies) in early endosomes and direct the receptor complex to the proteasome for degradation

  4. Overexpression of SOCS2 inverted these phenotypes generated by hsv2-miR (show MLXIP Antibodies)-H9-5p, indicating the potential roles of SOCS2 in Hsv2-miR (show MLXIP Antibodies)-H9-5p-driven metastasis in lung cancers. The results highlighted that Hsv2-miR (show MLXIP Antibodies)-H9-5p regulated and contributed to bone metastasis of lung cancers. We proposed that Hsv2-miR (show MLXIP Antibodies)-H9-5p could be used as a potential target in lung cancer therapy

  5. Overexpression of SOCS-2 is associated with hepatocellular carcinoma.

  6. focus on SOCS2 and review its biological function as well as its implication in pathological processes

  7. SOCS2 may improve outcome of TBI in mice by regulating aspects of the neuroinflammatory response

  8. This study showed that there was significantly increased levels of SOCS-2 mRNA in elderly and Alzheimer's disease brains.

  9. crystals of SOCS2 in complex with its adaptor proteins, Elongin C (show TCEB1 Antibodies) and Elongin B (show TCEB2 Antibodies), underwent a change in crystallographic parameters when treated with dimethyl sulfoxide during soaking experiments.

  10. miR (show MLXIP Antibodies)-101 functions as a growth-suppressive miRNA in H. pylori related GC, and that its suppressive effects are mediated mainly by repressing SOCS2 expression.

Mouse (Murine) Suppressor of Cytokine Signaling 2 (SOCS2) interaction partners

  1. Our data show that absence of SOCS2 turns cardiomyocytes unresponsive to LIF (show LIF Antibodies)-induced [Ca(2 (show CA2 Antibodies)+)] raise, indicating that endogenous levels of SOCS2 are crucial for full activation of LIF (show LIF Antibodies) signaling in the heart.

  2. Knockdown of SOCS2 makes mice less sensitive to multiple low dose streptozotocin.

  3. Study provides an insight into the role of SOCS2 in modulating the immune response to Bovine herpesvirus 5 [BoHV-5]infection.

  4. Data (including data from studies in knockout mice) suggest Socs2 regulates liver regeneration rate after partial hepatectomy, Ghr (growth hormone receptor (show GHR Antibodies)) level via ubiquitination/proteolysis, and serum Igf1 (insulin-like growth factor-1 (show IGF1 Antibodies)) level.

  5. GH appears to act directly on the metatarsals of Socs2(-/-) mice, promoting growth via a mechanism that is independent of IGF-1 (show IGF1 Antibodies).

  6. comparison of murine wt and Socs2(-/-) HSC (show FUT1 Antibodies) gene expression in response to 5-FU revealed a significant overlap with the molecular programs that correlate with SOCS2 expression in leukemias, particularly with the oncogenic pathways

  7. Studies indicate the critical role of suppressor of cytokine signaling 2 (SOCS2) in ontrolling the local growth hormone (GH (show GH1 Antibodies)) anabolic bone effects.

  8. Taken together, our observations indicated that SOCS2 could suppress myotube formation, act as an anti-regulator of mitochondria biogenesis via inhibiting p38 MAPK (show MAPK14 Antibodies) signal pathway.

  9. SOCS2 immunoprecipitates with TrkA (show NTRK1 Antibodies) and a juxtamembrane motif of TrkA (show NTRK1 Antibodies) is required for this interaction. Over-expression of SOCS2 in PC12 Tet-On cells increased total and surface TrkA (show NTRK1 Antibodies) expression. SOCS2 regulates neurite outgrowth.

  10. Results show that CISH (show CISH Antibodies) has no non-redundant functions in beta cell proliferation or glucose homeostasis during pregnancy in mice. Socs2 might compensate for the loss of Cish (show CISH Antibodies) during pregnancy.

Pig (Porcine) Suppressor of Cytokine Signaling 2 (SOCS2) interaction partners

Cow (Bovine) Suppressor of Cytokine Signaling 2 (SOCS2) interaction partners

  1. hepatic growth hormone receptor (show GHR Antibodies) and suppressor of cytokine signaling (SOCS (show CISH Antibodies))2 messenger RNA expression appeared to be promptly and sensitively regulated by increased estradiol levels before ovulation of dairy heifers

  2. relative amount of suppressors of cytokine signaling-2 (SOCS-2)messenger RNA increased after parturition

SOCS2 Antigen Profile

Antigen Summary

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SOCS2

  • suppressor of cytokine signaling 2 (SOCS2) antibody
  • suppressor of cytokine signaling 2 (socs2) antibody
  • suppressor of cytokine signaling 2 (LOC100229201) antibody
  • suppressor of cytokine signaling 2 (Socs2) antibody
  • 8030460M17 antibody
  • AI527257 antibody
  • AW108012 antibody
  • CIS2 antibody
  • Cish2 antibody
  • D130043N08Rik antibody
  • hg antibody
  • JAB antibody
  • si:dkey-202b22.1 antibody
  • Socs-2 antibody
  • socs2 antibody
  • SSI-2 antibody
  • SSI2 antibody
  • STATI2 antibody

Protein level used designations for SOCS2

suppressor of cytokine signaling-2 , suppressor of cytokine signaling 2 , suppressor of cytokine signaling 2 variant 1 , CIS-2 , STAT induced STAT inhibitor-2 , STAT-induced STAT inhibitor 2 , STAT-induced STAT inhibitor-2 , cytokine-inducible SH2 protein 2 , cytokine inducible SH2-containing protein 2 , SOCS-2 , suppressor of cytokine signalling 2

452127 Pan troglodytes
562062 Danio rerio
100144308 Takifugu rubripes
100144375 Oryzias latipes
100190869 Gasterosteus aculeatus
100272211 Oncorhynchus mykiss
395219 Gallus gallus
100151723 Xenopus (Silurana) tropicalis
100229201 Taeniopygia guttata
8835 Homo sapiens
216233 Mus musculus
482603 Canis lupus familiaris
100037966 Sus scrofa
338437 Bos taurus
84607 Rattus norvegicus
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