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anti-Mouse (Murine) SOCS2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS2 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies
  • 8030460M17
  • AI527257
  • AW108012
  • cis2
  • CIS2
  • cish2
  • Cish2
  • D130043N08Rik
  • hg
  • JAB
  • si:dkey-202b22.1
  • Socs-2
  • SOCS-2
  • socs-2
  • socs2
  • ssi-2
  • SSI-2
  • SSI2
  • ssi2
  • stati2
  • STATI2
Epitope
AA 48-90
15
5
5
4
3
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
50
18
16
3
3
2
2
Host
Rabbit
46
5
2
Clonality
Polyclonal
Conjugate
This SOCS2 antibody is un-conjugated
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
37
14
10
9
8
1
1
1
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Catalog No. ABIN736028
$ 269.50
Plus shipping costs $45.00

Top referenced anti-SOCS2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-SOCS2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 5 Antibodies 6 Antibodies 11 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 4 Antibodies 4 Antibodies 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies 1 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 15 Antibodies 15 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies

General

Antigen Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies
Epitope AA 48-90
(15), (5), (5), (4), (3), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(50), (18), (16), (3), (3), (2), (2)
Host Rabbit
(46), (5), (2)
Clonality
Polyclonal
Conjugate This SOCS2 antibody is un-conjugated
(1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(37), (14), (10), (9), (8), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-SOCS2 Antibody

Target Details SOCS2 Application Details Handling References for anti-SOCS2 Antibody (ABIN736028) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Socs 2
Isotype IgG

Target Details SOCS2

Product Details anti-SOCS2 Antibody Application Details Handling References for anti-SOCS2 Antibody (ABIN736028) Images back to top
Antigen
Alternative Name Socs 2 (SOCS2 Antibody Abstract)
Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subcellular location: Cytoplasm


Synonyms: CIS2, SSI2, Cish2, SSI-2, SOCS-2, STATI2, Suppressor of cytokine signaling 2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SOCS2
Gene ID 8835
UniProt O14508
Pathways JAK-STAT Signaling

Application Details

Product Details anti-SOCS2 Antibody Target Details SOCS2 Handling References for anti-SOCS2 Antibody (ABIN736028) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-SOCS2 Antibody Target Details SOCS2 Application Details References for anti-SOCS2 Antibody (ABIN736028) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-SOCS2 Antibody (ABIN736028)

Product Details anti-SOCS2 Antibody Target Details SOCS2 Application Details Handling Images back to top
Product cited in:

Letellier, Schmitz, Baig, Beaume, Schwartz, Frasquilho, Antunes, Marcon, Nazarov, Vallar, Even, Haan: "Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer." in: British journal of cancer, Vol. 111, Issue 4, pp. 726-35, 2014

Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, 2013