anti-Rat (Rattus) SOCS2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS2 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies
  • si:dkey-202b22.1
  • socs2
  • cis2
  • ssi2
  • cish2
  • ssi-2
  • socs-2
  • stati2
  • CIS2
  • Cish2
  • SOCS-2
  • SSI-2
  • SSI2
  • STATI2
  • 8030460M17
  • AI527257
  • AW108012
  • D130043N08Rik
  • JAB
  • hg
  • Socs-2
  • suppressor of cytokine signaling 2
  • SOCS2
  • socs2
  • LOC100229201
  • Socs2
Epitope
AA 48-90
12
5
4
3
3
3
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
51
29
20
6
6
5
4
2
1
1
1
Host
Rabbit
45
5
2
Clonality
Polyclonal
Conjugate
This SOCS2 antibody is un-conjugated
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
37
12
11
9
8
2
1
Options
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Catalog No. ABIN736028
$ 295.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4902291 ELISA IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-SOCS2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-SOCS2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 7 Antibodies 7 Antibodies 12 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 5 Antibodies 4 Antibodies 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies 2 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 25 Antibodies 19 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies

General

Antigen Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies
Epitope AA 48-90
(12), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(51), (29), (20), (6), (6), (5), (4), (2), (1), (1), (1)
Host Rabbit
(45), (5), (2)
Clonality
Polyclonal
Conjugate This SOCS2 antibody is un-conjugated
(2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(37), (12), (11), (9), (8), (2), (1)
Pubmed 3 references available
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Product Details anti-SOCS2 Antibody

Target Details SOCS2 Application Details Handling ProductDetails: References for anti-SOCS2 antibody (ABIN736028) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Socs 2
Isotype IgG

Target Details SOCS2

Product Details anti-SOCS2 Antibody Application Details Handling ProductDetails: References for anti-SOCS2 antibody (ABIN736028) Images back to top
Antigen
Alternative Name Socs 2 (SOCS2 Antibody Abstract)
Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subcellular location: Cytoplasm

Synonyms: CIS2, SSI2, Cish2, SSI-2, SOCS-2, STATI2, Suppressor of cytokine signaling 2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SOCS2

Gene ID 8835
UniProt O14508
Pathways JAK-STAT Signaling, Response to Growth Hormone Stimulus

Application Details

Product Details anti-SOCS2 Antibody Target Details SOCS2 Handling ProductDetails: References for anti-SOCS2 antibody (ABIN736028) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-SOCS2 Antibody Target Details SOCS2 Application Details ProductDetails: References for anti-SOCS2 antibody (ABIN736028) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-SOCS2 antibody (ABIN736028)

Product Details anti-SOCS2 Antibody Target Details SOCS2 Application Details Handling Images back to top
Product cited in:

Shin, Riew, Park, Pak, Lee: "Expression of SOCS2 mRNA and protein in the ischemic core and penumbra after transient focal cerebral ischemia in rats." in: Cell and tissue research, Vol. 364, Issue 1, pp. 67-81, 2016

Letellier, Schmitz, Baig, Beaume, Schwartz, Frasquilho, Antunes, Marcon, Nazarov, Vallar, Even, Haan: "Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer." in: British journal of cancer, Vol. 111, Issue 4, pp. 726-35, 2014

Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, 2013