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anti-Rat (Rattus) SOCS2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS2 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies
  • 8030460M17
  • AI527257
  • AW108012
  • cis2
  • CIS2
  • cish2
  • Cish2
  • D130043N08Rik
  • hg
  • JAB
  • si:dkey-202b22.1
  • Socs-2
  • SOCS-2
  • socs-2
  • socs2
  • ssi-2
  • SSI-2
  • SSI2
  • ssi2
  • stati2
  • STATI2
Epitope
AA 48-90
15
5
5
4
3
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
48
16
14
3
3
2
2
Host
Rabbit
44
5
2
Clonality
Polyclonal
Conjugate
This SOCS2 antibody is un-conjugated
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
35
13
10
9
8
1
1
1
Supplier
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Catalog No. ABIN736028
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089818385 ABIN1871055 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-SOCS2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

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Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 5 Antibodies 6 Antibodies 11 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 4 Antibodies 4 Antibodies 8 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 2 Antibodies 1 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 14 Antibodies 14 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies

General

Antigen Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies
Epitope AA 48-90
(15), (5), (5), (4), (3), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(48), (16), (14), (3), (3), (2), (2)
Host Rabbit
(44), (5), (2)
Clonality
Polyclonal
Conjugate This SOCS2 antibody is un-conjugated
(1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(35), (13), (10), (9), (8), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-SOCS2 Antibody

Target Details SOCS2 Application Details Handling References for anti-SOCS2 Antibody (ABIN736028) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Socs 2
Isotype IgG

Target Details SOCS2

Product Details anti-SOCS2 Antibody Application Details Handling References for anti-SOCS2 Antibody (ABIN736028) Images back to top
Antigen
Alternative Name Socs 2 (SOCS2 Antibody Abstract)
Background

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subcellular location: Cytoplasm


Synonyms: CIS2, SSI2, Cish2, SSI-2, SOCS-2, STATI2, Suppressor of cytokine signaling 2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SOCS2
Gene ID 8835
UniProt O14508
Pathways JAK-STAT Signaling

Application Details

Product Details anti-SOCS2 Antibody Target Details SOCS2 Handling References for anti-SOCS2 Antibody (ABIN736028) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-SOCS2 Antibody Target Details SOCS2 Application Details References for anti-SOCS2 Antibody (ABIN736028) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-SOCS2 Antibody (ABIN736028)

Product Details anti-SOCS2 Antibody Target Details SOCS2 Application Details Handling Images back to top
Product cited in:

Letellier, Schmitz, Baig, Beaume, Schwartz, Frasquilho, Antunes, Marcon, Nazarov, Vallar, Even, Haan: "Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer." in: British journal of cancer, Vol. 111, Issue 4, pp. 726-35, 2014

Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, 2013