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|Application / Reactivity||Human||Rat (Rattus)|
|Western Blotting (WB)||33 Antibodies||14 Antibodies|
|Immunoprecipitation (IP)||10 Antibodies||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||9 Antibodies||2 Antibodies|
|Immunohistochemistry (IHC)||8 Antibodies||4 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||1 Antibodies||1 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|ELISA||11 Antibodies||5 Antibodies|
|Antigen||Suppressor of Cytokine Signaling 2 (SOCS2) Antibodies|
|Epitope||AA 96-198 Alternatives|
|Reactivity||Human, Rat (Rattus) Alternatives|
|Conjugate||This SOCS2 antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-SOCS2 AntibodyTarget Details SOCS2 Application Details Handling Images
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 2(SOCS2) detection. Tested with WB in Human,Rat.
Gene Name: suppressor of cytokine signaling 2
Protein Name: Suppressor of cytokine signaling 2
|Purification||Immunogen affinity purified.|
|Immunogen||E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.|
Target Details SOCS2Product Details anti-SOCS2 Antibody Application Details Handling Images back to top
|Alternative Name||SOCS2 (SOCS2 Antibody Abstract)|
|Background||Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.|
|Research Area||Signaling, Innate Immunity, Cytokines|
Application DetailsProduct Details anti-SOCS2 Antibody Target Details SOCS2 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat , The detection limit for SOCS2 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-SOCS2 Antibody Target Details SOCS2 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
ImagesProduct Details anti-SOCS2 Antibody Target Details SOCS2 Application Details Handling back to top