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anti-Human SOCS4 antibody for Immunoprecipitation

Recommended SOCS4 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 4 (SOCS4) Antibodies
  • 3110032M18Rik
  • A730004F22Rik
  • AI427843
  • AU015727
  • AU015859
  • SOCS4
  • socs4
  • Socs4
  • socs4a
  • SOCS6
  • socs6l
  • Socs7
  • socs7
  • SOCS7
  • wu:fb77f06
  • zgc:64107
Epitope
C-Term
27
22
21
16
15
5
3
3
3
2
2
1
1
1
Reactivity
Human
82
4
4
3
1
1
1
Host
Rabbit
62
17
5
Clonality
Polyclonal
Conjugate
This SOCS4 antibody is un-conjugated
5
5
5
5
5
5
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
63
50
23
18
11
8
5
2
1
1
Supplier
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Catalog No. ABIN302741
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089235755 ABIN213829 IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal
0.00089235755 ABIN2469622 IP IHC WB Rabbit C-Term Log in to see Polyclonal
0.00089235755 ABIN1739510 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
0.00089235755 ABIN2364300 IP IHC WB Rabbit C-Term Log in to see Polyclonal
0.00089235755 ABIN2767593 IP IHC (p) WB Rabbit C-Term Log in to see Polyclonal

Similar anti-SOCS4 Antibodies

Application / Reactivity Human
ELISA 48 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 18 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies
Immunohistochemistry (IHC) 23 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 62 Antibodies

General

Antigen Suppressor of Cytokine Signaling 4 (SOCS4) Antibodies
Epitope C-Term
(27), (22), (21), (16), (15), (5), (3), (3), (3), (2), (2), (1), (1), (1)
Reactivity Human
(82), (4), (4), (3), (1), (1), (1)
Host Rabbit
(62), (17), (5)
Clonality
Polyclonal
Conjugate This SOCS4 antibody is un-conjugated
(5), (5), (5), (5), (5), (5)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(63), (50), (23), (18), (11), (8), (5), (2), (1), (1)
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Product Details anti-SOCS4 Antibody

Target Details SOCS4 Application Details Handling Images
Specificity This antibody recognizes Suppressor of cytokine signaling 4 (SOCS4).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography.
Immunogen Synthetic peptide KLH conjugated from the C-terminus of Hman SOCS4. Genename: SOCS4

Target Details SOCS4

Product Details anti-SOCS4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SOCS4 (SOCS4 Antibody Abstract)
Background Accumulating evidence has demonstrated that cytokine receptor signaling is negatively regulated by a family of Src homology 2 domain-containing adaptor molecules termed SOCS (Suppressor of Cytokine Signaling) (1-3). Currently, there are eight members of the SOCS family that have been recognized, SOCS-1, -2, -3, -4, - 5, -6, -7 and CIS. Structurally, the SOCS proteins are composed of an N-terminus region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C-terminus motif that has been called the SOCS box (4). The SOCS proteins appear to form part of a classical negative feed back loop that regulates cytokine signal transduction via a STATinduced transcriptional mechanism (5). Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. Within the SOCS subfamily, SOCS-4, SOCS-5, SOCS-6, SOCS-7 remain poorly understood (6). On the basis of structural considerations, it would be expected that SOCS-4, -5, -6, and -7, like SOCS-1, SOCS-2, SOCS-3 and CIS, act to negatively regulate signal transduction (4), but it is uncertain which specific cytokine is involved (7-9).Synonyms: SOCS-4, SOCS-7, SOCS7, Suppressor of cytokine signaling 4, Suppressor of cytokine signaling 7
Gene ID 122809
NCBI Accession NP_543143
UniProt Q8WXH5
Research Area Signaling
Pathways JAK-STAT Signaling, EGFR Signaling Pathway

Application Details

Product Details anti-SOCS4 Antibody Target Details SOCS4 Handling Images back to top
Application Notes Immunoprecipitation: 3-5 ng/IE6 cells. Western Blot: 0.5-2 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-SOCS4 Antibody Target Details SOCS4 Application Details Images back to top
Concentration 0.2 mg/mL
Buffer PBS, pH 7.4, 0.05 % Soduim Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-SOCS4 Antibody Target Details SOCS4 Application Details Handling back to top
Supplier Images
 image for anti-SOCS4 antibody (Suppressor of Cytokine Signaling 4) (C-Term) (ABIN302741) anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibody