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Browse our SOCS5 Proteins (SOCS5)

Full name:
Suppressor of Cytokine Signaling 5 Proteins (SOCS5)
On www.antibodies-online.com are 5 Suppressor of Cytokine Signaling 5 (SOCS5) Proteins from 3 different suppliers available. Additionally we are shipping SOCS5 Antibodies (64) and many more products for this protein. A total of 77 SOCS5 products are currently listed.
Synonyms:
1810018L08Rik, CIS6, Cish5, CISH6, GB18949, mKIAA0671, RGD1564914, SOCS-5, socs5, zgc:153506
list all proteins Gene Name GeneID UniProt
SOCS5 9655 O75159
SOCS5 56468 O54928
Rat SOCS5 SOCS5 500616  

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SOCS5 Proteins (SOCS5) by Origin

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More Proteins for SOCS5 Interaction Partners

Human Suppressor of Cytokine Signaling 5 (SOCS5) interaction partners

  1. Opisthorchis felineus infection diminishes the risk of atopic bronchial asthma associated with the SOCS5 gene polymorphism.

  2. different domains in SOCS5 contribute to two distinct mechanisms for regulation of cytokine and growth factor signaling with JAK1 (show JAK1 Proteins) and SHC-1 (show SHC1 Proteins)

  3. The rs6737848 SOCS5 polymorphism was significantly associated with asthma in additive model and in dominant model

  4. Exogenous miR (show MLXIP Proteins)-9 effectively reduced SOCS5 levels, leading to activated JAK (show JAK3 Proteins)-STAT (show STAT1 Proteins) pathway, which promoted endothelial cell migration and tumour angiogenesis

  5. Identified is a conserved region of about 70 residues in the N-terminal domains of SOCS4 (show SOCS6 Proteins) and 5 that is predicted to be more ordered than the surrounding sequence.

  6. The results may contribute to understanding SOCS5 and SOCS6 (show SOCS6 Proteins) expression regulation in various cancer tissues, and show that these two factors may be used for diagnosing cancer.

  7. Up regulation of SOCS1 (show SOCS1 Proteins) and SOCS5 expression and down-regulation of SOCS3 (show SOCS3 Proteins) and CIS (show CISH Proteins) may correlate with the development of a Th1 (show TH1L Proteins) mediated immune response in Vogt-Koyanagi-Harada disease.

  8. The reduction in EGFR (show EGFR Proteins) levels and EGF (show EGF Proteins)-induced signaling in SOCS5-expressing cells requires both the Src (show SRC Proteins) homology-2 and SOCS (show CISH Proteins) box domains of SOCS5.

  9. Constitutive expression of SOCS5 in transgenic mice results in reduced eosinophil infiltration in allergic conjunctivitis

Mouse (Murine) Suppressor of Cytokine Signaling 5 (SOCS5) interaction partners

  1. have identified a phosphorylation site (Ser211) within the JIR of mSOCS5 and have investigated the role of phosphorylation in modulating JAK (show JAK3 Proteins) binding using site-directed mutagenesis.

  2. Identified is a conserved region of about 70 residues in the N-terminal domains of Socs4 (show SOCS6 Proteins) and 5 that is predicted to be more ordered than the surrounding sequence.

  3. The effect of Flt3 (show FLT3 Proteins)-L on Th17 cells and expression of suppressors of cytokine signaling (SOCS (show CISH Proteins)) proteins in the lungs of house dust mite (HDM (show HDAC3 Proteins))-sensitized and -challenged mice, was evaluated.

  4. SOCS5 regulates Th1 (show HAND1 Proteins)/Th2 cell balance and suppresses IL-4 (show IL4 Proteins)

  5. SOCS5-deficient CD4 (show CD4 Proteins) T cells showed no abnormalities in Th1 (show HAND1 Proteins)/Th2 differentiation and Socs5(-/-) mice showed normal resistance to infection with Leishmania major.

  6. SOCS-5 associated with the EGF-R (show EGFR Proteins) complex in an EGF (show EGF Proteins)-independent manner

  7. Adoptive transfer of SOCS5Tg-CD4 (show CD4 Proteins)+ T cells into T- and B cell-deficient RAG-2 (show RAG2 Proteins)(-/-) mice resulted in augmented leukocyte infiltration and increased peritoneal levels of IL-12 (show IL12A Proteins), IFN-gamma (show IFNG Proteins), and TNF-alpha (show TNF Proteins) after cecal ligation and puncture

SOCS5 Protein Profile

Protein Summary

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Alternative names and synonyms associated with SOCS5

  • suppressor of cytokine signaling 5 (SOCS5)
  • suppressor of cytokine signaling 5 (socs5)
  • suppressor of cytokine signaling 5 (Socs-5)
  • suppressor of cytokine signaling 5a (socs5a)
  • suppressor of cytokine signaling 5 (Tsp_07018)
  • suppressor of cytokine signaling 5 (Socs5)
  • 1810018L08Rik protein
  • CIS6 protein
  • Cish5 protein
  • CISH6 protein
  • GB18949 protein
  • mKIAA0671 protein
  • RGD1564914 protein
  • SOCS-5 protein
  • socs5 protein
  • zgc:153506 protein

Protein level used designations for SOCS5

suppressor of cytokine signaling 5 , suppressor of cytokine signaling 5-like , CIS-6 , cytokine-inducible SH2 protein 6 , cytokine-inducible SH2-containing protein 5 , SOCS-5 , cytokine inducible SH2-containing protein 5

GENE ID SPECIES
428570 Gallus gallus
459209 Pan troglodytes
474581 Canis lupus familiaris
549598 Xenopus (Silurana) tropicalis
552036 Apis mellifera
714998 Macaca mulatta
768142 Danio rerio
10903311 Trichinella spiralis
100144376 Oryzias latipes
100393834 Callithrix jacchus
100437083 Pongo abelii
100499594 Oncorhynchus mykiss
100580253 Nomascus leucogenys
100190883 Gasterosteus aculeatus
100381168 Xenopus laevis
9655 Homo sapiens
100302367 Sus scrofa
514773 Bos taurus
56468 Mus musculus
500616 Rattus norvegicus
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