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anti-Human SOCS6 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS6 Antibody (supplied by: Log in to see )

Antigen
Suppressor of Cytokine Signaling 6 (SOCS6) Antibodies
  • 1500012M23Rik
  • 5830401B18Rik
  • AI447482
  • CIS-4
  • CIS4
  • Cis4
  • Cish4
  • HSPC060
  • MGC81477
  • SOCS-4
  • SOCS-6
  • Socs4
  • SOCS4
  • SOCS6
  • socs6
  • SSI4
  • STAI4
  • STATI4
Epitope
AA 40-69, N-Term
19
15
9
7
6
2
2
1
Reactivity
Human
50
10
5
Host
Rabbit
42
7
1
Clonality
Polyclonal
Conjugate
This SOCS6 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
29
23
5
1
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Catalog No. ABIN658039
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN1687729 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN1687640 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN373895 IHC (p) Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN1809517 IHC (p) WB Rabbit AA 39-69 Log in to see Polyclonal
0.0008982679 ABIN444521 IHC (p) IHC Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-SOCS6 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-SOCS6 Antibodies

Application / Reactivity Human
ELISA 29 Antibodies
Immunohistochemistry (IHC) 23 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 40 Antibodies

General

Antigen Suppressor of Cytokine Signaling 6 (SOCS6) Antibodies
Epitope AA 40-69, N-Term
(19), (15), (9), (7), (6), (2), (2), (1)
Reactivity Human
(50), (10), (5)
Host Rabbit
(42), (7), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This SOCS6 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(39), (29), (23), (5), (1)
Pubmed 2 references available
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Product Details anti-SOCS6 Antibody

Target Details SOCS6 Application Details Handling References for anti-SOCS6 Antibody (ABIN658039) Images
Specificity This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-69 amino acids from the N-terminal region of human SOCS6.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 AA from the N-terminal region of human SOCS6.
Clone RB34150
Isotype Ig

Target Details SOCS6

Product Details anti-SOCS6 Antibody Application Details Handling References for anti-SOCS6 Antibody (ABIN658039) Images back to top
Antigen
Alternative Name SOCS6 (SOCS6 Antibody Abstract)
Background The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Synonyms: Suppressor of cytokine signaling 6,SOCS6,CIS4, SOCS4
Molecular Weight 59528 DA
Gene ID 9306
NCBI Accession NP_004223
UniProt O14544
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Pathways JAK-STAT Signaling

Application Details

Product Details anti-SOCS6 Antibody Target Details SOCS6 Handling References for anti-SOCS6 Antibody (ABIN658039) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-SOCS6 Antibody Target Details SOCS6 Application Details References for anti-SOCS6 Antibody (ABIN658039) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SOCS6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months

References for anti-SOCS6 Antibody (ABIN658039)

Product Details anti-SOCS6 Antibody Target Details SOCS6 Application Details Handling Images back to top
Background publications

Choi, Son, Park, Shin, Yun: "SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7271-80, 2010

Lai, Wang, Yang, Chen: "Genomic organization and functional characterization of the promoter for the human suppressor of cytokine signaling 6 gene." in: Gene, Vol. 448, Issue 1, pp. 64-73, 2009

Images

Product Details anti-SOCS6 Antibody Target Details SOCS6 Application Details Handling References for anti-SOCS6 Antibody (ABIN658039) back to top
Supplier Images
Western Blotting (WB) image for anti-SOCS6 antibody (Suppressor of Cytokine Signaling 6) (AA 40-69) (ABIN658039) SOCS6 Antibody (N-term) (ABIN658039) western blot analysis in 293 cell line lysates (...