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Browse our anti-SRC (SRC) Antibodies

Full name:
anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) Antibodies (SRC)
On www.antibodies-online.com are 416 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies from 28 different suppliers available. Additionally we are shipping SRC Kits (17) and SRC Proteins (13) and many more products for this protein. A total of 471 SRC products are currently listed.
Synonyms:
ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b
list all antibodies Gene Name GeneID UniProt
SRC 20779 P05480
SRC 6714 P12931
SRC 83805  

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All available anti-SRC Antibodies

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Top referenced anti-SRC Antibodies

  1. Human Polyclonal SRC Primary Antibody for FACS, IF - ABIN1881833 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. in Cell stem cell 2010 (PubMed)
    Show all 5 references for ABIN1881833

  2. Human Polyclonal SRC Primary Antibody for WB - ABIN1881832 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881832

  3. Human Monoclonal SRC Primary Antibody for IF, WB - ABIN387822 : Chen, Li, Zhang, Yi, Chen, Wang, Zhang: Src-stimulated IRTKS phosphorylation enhances cell migration. in FEBS letters 2011 (PubMed)
    Show all 2 references for ABIN387822

  4. Human Polyclonal SRC Primary Antibody for IHC, ELISA - ABIN1533006 : Xu, Harrison, Eck: Three-dimensional structure of the tyrosine kinase c-Src. in Nature 1997 (PubMed)
    Show all 2 references for ABIN1533006

  5. Human Polyclonal SRC Primary Antibody for IHC, ELISA - ABIN1531972 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. in Cell 2005 (PubMed)
    Show all 2 references for ABIN1531972

  6. Human Monoclonal SRC Primary Antibody for FACS, IHC - ABIN969418 : Byers, Sen, Saigal, Diao, Wang, Nanjundan, Cascone, Mills, Heymach, Johnson: Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)

  7. Human Polyclonal SRC Primary Antibody for IHC, ELISA - ABIN1532080 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  8. Cow (Bovine) Polyclonal SRC Primary Antibody for WB - ABIN2779668 : Pechkovsky, Scaffidi, Hackett, Ballard, Shaheen, Thompson, Thannickal, Knight: Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against SRC Interaction Partners

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. results suggest that LPS (show TLR4 Antibodies)-stimulated macrophage mediators attenuate both FAK (show PTK2 Antibodies) and Src activations in osteoblast, suggesting a novel role for TNFalpha (show TNF Antibodies) on osteoblast performance

  2. Src has a role in priming Pyk2 (show PTK2B Antibodies) (but not FAK (show PTK2 Antibodies)) phosphorylation and subsequent activation downstream of integrins

  3. Heritable pulmonary arterial hypertension (PAH) results from increased SRC activation, cellular contraction, and vascular resistance, but antagonism of HTR2B prevents SRC phosphorylation and development of PAH.

  4. Periodic axial motility of epithelial basal cell projections is controlled by c-Src.

  5. mutation of the five Src-modified residues to aspartate but not phenylalanine allows Runx1 (show RUNX1 Antibodies) to increase Cebpa (show CEBPA Antibodies) and granulocyte colony formation by Runx1 (show RUNX1 Antibodies)-deleted murine marrow.

  6. This study provides an additional mechanistic link between Angiotensin II and vasoconstriction via SFK-enhanced MLC phosphorylation in smooth muscle cells.

  7. Src/Syk (show SYK Antibodies)-dependent signalling stabilises platelet adhesion to podoplanin (show PDPN Antibodies)

  8. FAK (show PTK2 Antibodies)-regulated signalling module PDK1 (show PDPK1 Antibodies)-Akt (show AKT1 Antibodies)-p70S6K (show RPS6KB1 Antibodies) that controls Src's intracellular trafficking operates at Src-containing autophagosomes.

  9. suggest that Reelin (show RELN Antibodies)-dependent signaling mechanisms may be split into Src-AKT (show AKT1 Antibodies)-dependent and Src-Go-dependent pathways

  10. Src contributed to tyrosine phosphorylation of ELMO1 at Y720 and Y724 residues, which was crucial for activation of Rac1, followed by the promoting cell adhesion, spreading, and migration.

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (show TMOD4 Antibodies) (CP) alphabeta heterodimer, which regulates actin (show ACTB Antibodies) filament (F-actin (show ACTB Antibodies)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (show MAPK8 Antibodies) activation.

  6. Dumbfounded/Neph1 (show NEPH1 Antibodies), a key diaphragm constituent, is a target of the Src kinase (show CSK Antibodies) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (show NEPH1 Antibodies) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A (show PPP2R2B Antibodies)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (show ACTB Antibodies) formation and Jun kinase (show MAPK9 Antibodies) activation in plasmatocytes.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Src expression showed a significantly positive linear relationship with RANK, suggesting a potential mechanism of the RANKL (show TNFSF11 Antibodies)-RANK axis in regulating breast cancer cell differentiation and antiapoptosis.

  2. Data suggest 17beta-estradiol stimulates odontoblastic differentiation of dental pulp via coordinated regulation of estrogen receptor alpha (show ESR1 Antibodies), c-Src, and MAP kinase (show MAPK1 Antibodies) signaling pathways, which may play key role in calcification/regeneration of dentin.

  3. This study describes a pro-metastatic EGFR (show EGFR Antibodies)/Src-dependent beta4 integrin/FAK (show PTK2 Antibodies) complex that is involved in breast cancer malignancy and is a novel therapeutic target for triple-negative breast cancer.

  4. FGF-2 (show FGF2 Antibodies), VEGF-A (show VEGFA Antibodies), and HIV-Tat (show TAT Antibodies), may affect the glomerular filtration barrier in HIV+ children through the induction of synergistic changes in Rho-A (show RHOA Antibodies) and Src activity

  5. our integrative approach enabled the discovery of a new model where Src is de-activated in coordination with membrane protrusion, providing important insights into the regulation of endothelial migration and angiogenesis.

  6. Data show that src kinases (SRC) and mitogen-activated protein kinase kinase 1 (MEK (show MAP2K1 Antibodies)) co-inhibition by saracatinib and PD0325901 respectively can be broadly effective in tumor growth control of a wide panel of non-small cell lung cancer (NSCLC) cell lines.

  7. Collectively, our data demonstrate that DCMF induces cell migration and promotes wound healing through activation of Src/FAK (show PTK2 Antibodies), ERK (show EPHB2 Antibodies), AKT (show AKT1 Antibodies), and p38 MAPK (show MAPK14 Antibodies) signaling.

  8. In marked contrast to invadopodia, this degradation does not require the action of Src kinase (show CSK Antibodies), Cdc42 (show CDC42 Antibodies) or Dyn2 (show DNM2 Antibodies). Rather, inhibition of Dyn2 (show DNM2 Antibodies) causes a marked upregulation of stromal matrix degradation

  9. Data suggest that Src kinases inhibitors may act with different mechanisms in non-small cell lung cancer (NSCLC) depending on EGF receptor (EGFR (show EGFR Antibodies))/Ras protein (Ras) mutational profile.

  10. regulation of c-Src trafficking requires both microtubules and actin polymerization, and GEF-H1 coordinates c-Src trafficking, acting as a molecular switch between these two mechanisms

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. RhoA (show RHOA Antibodies) and membrane fluidity mediates the spatially polarized Src/FAK (show PTK2 Antibodies) activation in response to shear stress.

  2. AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.

  3. The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.

  4. src has a role in activation of 5'-AMP (show TMPRSS5 Antibodies)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  5. results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network

  6. These results suggest that TGF-beta1 (show TGFB1 Antibodies)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (show PTK2 Antibodies)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Src kinase (show CSK Antibodies) mediates hypoxia-induced caspase-1 (show CASP1 Antibodies) activation in the cerebral cortex of newborn piglets

  2. Expression of mutant alpha1 Na/K-ATPase (show ATP1A1 Antibodies) defective in conformational transition attenuates Src-mediated signal transduction

  3. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC Antigen Profile

Antigen Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC) antibody
  • proto-oncogene tyrosine-protein kinase src (AaeL_AAEL002471) antibody
  • proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) antibody
  • Rous sarcoma oncogene (Src) antibody
  • Src oncogene at 64B (Src64B) antibody
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC) antibody
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Src) antibody
  • v-src sarcoma viral oncogene (SRC) antibody
  • ASV antibody
  • AW259666 antibody
  • c-Src antibody
  • C-src1 antibody
  • CG7524 antibody
  • D-src antibody
  • D-Src64B antibody
  • Dmel\CG7524 antibody
  • DmHD-358 antibody
  • Dm SRC1 antibody
  • dsrc antibody
  • Dsrc64 antibody
  • Dsrc64B antibody
  • HD-358 antibody
  • MRE5 antibody
  • p60-Src antibody
  • PP60C-SCR antibody
  • pp60c-src antibody
  • SDR antibody
  • src antibody
  • SRC1 antibody
  • src64 antibody
  • SRC 64B antibody
  • src64b antibody

Protein level used designations for SRC

proto-oncogene tyrosine-protein kinase SRC , proto-oncogene tyrosine-protein kinase src , neuronal proto-oncogene tyrosine-protein kinase Src , p60-Src , proto-oncogene c-Src , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , proto-oncogene tyrosine-protein kinase Src , protooncogene SRC, Rous sarcoma , tyrosine kinase pp60c-src , tyrosine-protein kinase SRC-1 , Rous sarcoma oncogene , c-Src , pp60c-src , tyrosine protein kinase c-src , tyrosine protein kinase pp60-c-src , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , src oncogene , v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , non-tyrosine protein kinase

GENE ID SPECIES
458229 Pan troglodytes
5574802 Aedes aegypti
6043642 Culex quinquefasciatus
20779 Mus musculus
48973 Drosophila melanogaster
6714 Homo sapiens
83805 Rattus norvegicus
485864 Canis lupus familiaris
535742 Bos taurus
100154503 Sus scrofa
396442 Gallus gallus
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