anti-Human SRC antibody for Flow Cytometry

Recommended SRC Antibody (supplied by: Log in to see )

Antigen
V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies
  • AW259666
  • pp60c-src
  • C-src1
  • CG7524
  • D-Src64B
  • D-src
  • DSRC64
  • DSrc
  • DSrc64
  • DSrc64B
  • Dm SRC1
  • DmHD-358
  • Dmel\CG7524
  • Dsrc
  • Dsrc64
  • Dsrc64B
  • HD-358
  • MRE5
  • SRC 64B
  • Src
  • Src1
  • Src64
  • c-src
  • dSrc
  • dsrc
  • src
  • src1
  • src64
  • src64B
  • src64b
  • ASV
  • SRC1
  • c-SRC
  • p60-Src
  • c-Src
  • PP60C-SCR
  • SDR
  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • proto-oncogene tyrosine-protein kinase src
  • Rous sarcoma oncogene
  • Src oncogene at 64B
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • v-src sarcoma viral oncogene
  • SRC
  • AaeL_AAEL002471
  • CpipJ_CPIJ010659
  • Src
  • Src64B
Epitope
N-Term, AA 24-52
60
42
39
34
27
23
20
15
12
11
8
6
6
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
434
245
199
30
17
16
13
11
9
7
6
5
5
4
4
4
2
1
1
1
1
1
1
Host
Rabbit
378
78
1
1
Clonality
Polyclonal
Conjugate
This SRC antibody is un-conjugated
19
19
15
14
13
13
3
3
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
383
206
149
56
38
32
27
20
13
9
7
5
3
3
1
Options
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Catalog No. ABIN1881833
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.052211 ABIN969418 FACS IHC ELISA WB Mouse IgG1 Log in to see 1F11 1
14.052211 ABIN4355874 ELISA FACS IHC WB Mouse IgG1 Log in to see 1F11
14.052211 ABIN1846381 FACS IHC ELISA WB Mouse IgG1 Log in to see
1 ABIN1501123 ELISA FACS IHC (p) WB Mouse IgG1 Log in to see 1F11
1 ABIN4880477 ELISA FACS IHC WB Mouse IgG1 Log in to see 1F11
1 ABIN3029554 FACS IF IHC ELISA WB Rabbit Ig Fraction AA 24-52 Log in to see Polyclonal
1 ABIN2366318 FACS IHC ELISA WB Mouse IgG1 Log in to see 13B736
1 ABIN1839200 FACS IF IHC (p) WB Rabbit AA 24-52 Log in to see Polyclonal
1 ABIN5588733 ELISA FACS IHC (p) WB Mouse IgG1 Log in to see 1F11
1 ABIN5624407 FACS Rabbit IgG1 kappa pTyr416 Log in to see SrcY416-C4
1 ABIN2366387 IC FACS IP IHC WB Rabbit Log in to see 5i131
1 ABIN2793858 FACS IF IHC WB Rabbit Ig Fraction N-Term Log in to see Polyclonal
1 ABIN3060239 FACS IF/ICC IHC IP WB Rabbit Log in to see Polyclonal

General

Antigen V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies
Epitope N-Term, AA 24-52
(60), (42), (39), (34), (27), (23), (20), (15), (12), (11), (8), (6), (6), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(434), (245), (199), (30), (17), (16), (13), (11), (9), (7), (6), (5), (5), (4), (4), (4), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(378), (78), (1), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This SRC antibody is un-conjugated
(19), (19), (15), (14), (13), (13), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(383), (206), (149), (56), (38), (32), (27), (20), (13), (9), (7), (5), (3), (3), (1)
Pubmed 5 references available
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Product Details anti-SRC Antibody

Target Details SRC Application Details Handling References for anti-SRC antibody (ABIN1881833) Images
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This SRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human SRC.
Clone RB41141

Target Details SRC

Product Details anti-SRC Antibody Application Details Handling References for anti-SRC antibody (ABIN1881833) Images back to top
Antigen
Alternative Name SRC (SRC Antibody Abstract)
Background This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Synonyms: SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src
NCBI Accession NP_938033, NP_005408
UniProt P12931
Research Area Signaling
Pathways JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling

Application Details

Product Details anti-SRC Antibody Target Details SRC Handling References for anti-SRC antibody (ABIN1881833) Images back to top
Application Notes WB: 1:2000,IHC: 1:50,FACS: 1:50,IF: 1:50
Restrictions For Research Use only

Handling

Product Details anti-SRC Antibody Target Details SRC Application Details References for anti-SRC antibody (ABIN1881833) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-SRC antibody (ABIN1881833)

Product Details anti-SRC Antibody Target Details SRC Application Details Handling Images back to top
Product cited in:

Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: "Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner." in: Cell stem cell, Vol. 7, Issue 4, pp. 496-507, 2010

Pradhan, Alrehani, Patel, Khatlani, Vijayan: "Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29059-68, 2010

Dergai, Tsyba, Dergai, Zlatskii, Skrypkina, Kovalenko, Rynditch: "Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface." in: Biochemical and biophysical research communications, Vol. 399, Issue 2, pp. 307-12, 2010

Liu, Qiu, Li, Chen, Cao et al.: "Human phosphatidylethanolamine-binding protein 4 promotes transactivation of estrogen receptor alpha (ERalpha) in human cancer cells by inhibiting proteasome-dependent ERalpha degradation via ..." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 21934-42, 2010

Pene-Dumitrescu, Smithgall: "Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21446-57, 2010

Images

Product Details anti-SRC Antibody Target Details SRC Application Details Handling References for anti-SRC antibody (ABIN1881833) back to top
Supplier Images
Western Blotting (WB) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunohistochemistry (IHC) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunohistochemistry (IHC) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Flow Cytometry (FACS) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunofluorescence (IF) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunofluorescence (IF) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...