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anti-Rat (Rattus) SRC antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended SRC Antibody (supplied by: Log in to see )

Antigen
V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies
  • AW259666
  • pp60c-src
  • C-src1
  • CG7524
  • D-Src64B
  • D-src
  • DSRC64
  • DSrc
  • DSrc64
  • DSrc64B
  • Dm SRC1
  • DmHD-358
  • Dmel\CG7524
  • Dsrc
  • Dsrc64
  • Dsrc64B
  • HD-358
  • MRE5
  • SRC 64B
  • Src
  • Src1
  • Src64
  • c-src
  • dSrc
  • dsrc
  • src
  • src1
  • src64
  • src64B
  • src64b
  • ASV
  • SRC1
  • c-SRC
  • p60-Src
  • c-Src
  • PP60C-SCR
  • SDR
  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • proto-oncogene tyrosine-protein kinase src
  • Rous sarcoma oncogene
  • Src oncogene at 64B
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • v-src sarcoma viral oncogene
  • SRC
  • AaeL_AAEL002471
  • CpipJ_CPIJ010659
  • Src
  • Src64B
Epitope
pTyr215
59
32
30
27
25
24
18
15
15
11
11
8
8
6
5
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
408
238
193
31
17
16
13
11
9
6
5
5
5
4
4
2
2
1
1
1
1
1
1
Host
Rabbit
359
71
1
Clonality
Polyclonal
Conjugate
This SRC antibody is conjugated to Alexa Fluor 647
19
15
15
14
13
13
3
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
359
199
143
49
37
26
24
20
12
9
5
5
3
2
1
Options
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Catalog No. ABIN879252
$ 427.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2814994 IF (p) Alexa Fluor 594 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN712334 IF (p) Cy3 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN712338 IF (p) FITC Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN712337 IF (p) Cy7 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN712336 IF (p) Cy5.5 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN712335 IF (p) Cy5 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN879249 IF (p) Alexa Fluor 350 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN879253 IF (p) Alexa Fluor 555 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN879250 IF (p) Alexa Fluor 488 Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN2814991 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
1 ABIN712331 IF (p) IHC (p) WB Rabbit IgG pTyr215 Log in to see Polyclonal
1 ABIN916361 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN916357 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN916360 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN916358 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN733613 IF (p) IHC (p) WB Rabbit IgG pTyr529 Log in to see Polyclonal
1 ABIN738177 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN738176 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN738178 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN738174 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal

Similar anti-SRC Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 9 Antibodies 6 Antibodies 4 Antibodies
Western Blotting (WB) 338 Antibodies 197 Antibodies 158 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Staining (ICS) 3 Antibodies 3 Antibodies 3 Antibodies
Immunoprecipitation (IP) 21 Antibodies 10 Antibodies 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 50 Antibodies 36 Antibodies 33 Antibodies
Immunohistochemistry (IHC) 143 Antibodies 97 Antibodies 83 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 27 Antibodies

General

Antigen V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antibodies
Epitope pTyr215
(59), (32), (30), (27), (25), (24), (18), (15), (15), (11), (11), (8), (8), (6), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(408), (238), (193), (31), (17), (16), (13), (11), (9), (6), (5), (5), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(359), (71), (1)
Clonality
Polyclonal
Conjugate This SRC antibody is conjugated to Alexa Fluor 647
(19), (15), (15), (14), (13), (13), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(359), (199), (143), (49), (37), (26), (24), (20), (12), (9), (5), (5), (3), (2), (1)
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Product Details anti-SRC Antibody

Target Details SRC Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from mouse Src around the phosphorylation site of Tyr215
Isotype IgG

Target Details SRC

Product Details anti-SRC Antibody Application Details Handling Images back to top
Antigen
Alternative Name Src (SRC Antibody Abstract)
Background

Src (also known as pp60src) is a non receptor Tyrosine Kinase involved in signal transduction in many biological systems and implicated in the development of human tumors. There are two critical phosphorylation sites of tyrosine on Src, tyrosine 418 and tyrosine 529 (referring to human Src sequence). The tyrosine 418 is located in the catalytic domain and is one of the autophosphorylation sites. Full catalytic activity of Src requires phosphorylation of tyrosine 418. The tyrosine 529 is located near the carboxyl terminus of Src and acts as a negative regulator, in that Src is held in the inactive form through an intramolecular interaction between the SH2 domain and the carboxyl terminus when tyrosine 529 is phosphorylated by Csk. This conformation blocks phosphorylation of tyrosine 418 at the catalytic domain, thereby preventing Src activation. When tyrosine 529 is dephosphorylated, tyrosine 418 can be maximally phosphorylated and Src becomes active. Src is a proto oncogene that may play a role in the regulation of embryonic development and cell growth. Mutations in this gene could be involved in the malignant progression of colon cancer. Immunogen: Synthetic peptide (Human) derived from the region of Src that contains tyrosine 529, based on the human sequence. The sequence is conserved in mouse (tyrosine 534), chicken (tyrosine 527) and frog (tyrosine 525).


Synonyms: SRCphospho Y215, ASV, Avian sarcoma virus, c SRC, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA, cSrc, EC 2.7.10.2, Neuronal CSRC tyrosine specic protein kinase, Neuronal SRC, Oncogene SRC, OTTHUMP00000030931, OTTHUMP00000174476, OTTHUMP00000174477, p60 Src, p60-Src, p60Src, pp60c src, pp60c-src, pp60csrc, Proto oncogene tyrosine protein kinase Src, Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, Protooncogene SRC, protooncogene SRC Rous sarcoma, Src, SRC Oncogene, SRC_HUMAN, SRC1, Tyrosine kinase pp60c src, Tyrosine protein kinase SRC 1, Tyrosine protein kinase SRC1, v src avian sarcoma Schmidt Ruppin A2 viral oncogene homolog, V src sarcoma Schmidt Ruppin A 2 viral oncogene homolog avian, v src sarcoma Schmidt Ruppin A 2 viral oncogene homolog avian, vsrc avian sarcoma Schmidt Ruppin A2 viral oncogene homolog.
Gene ID 6714
Research Area Cancer, Transcription Factors, Tyrosine Kinases, Signaling
Pathways JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-SRC Antibody Target Details SRC Handling Images back to top
Application Notes IF(IHC-P)(1:50-200)
Comment

Exitation/Emission: 652nm/668nm

Restrictions For Research Use only

Handling

Product Details anti-SRC Antibody Target Details SRC Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at 4°C
Expiry Date 12 months