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anti-Frog STAT1 antibody for Intracellular Staining

Recommended STAT1 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
  • IMUP
  • H2RSP
  • IMUP-1
  • IMUP-2
  • 2010005J02Rik
  • AA408197
  • DD6G4-4
  • CANDF7
  • ISGF-3
  • STAT91
  • STAT4
  • XStat1
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
  • signal transducer and activator of transcription 1, 91kDa
  • RIKEN cDNA 2200002D01 gene
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 4
  • STAT1
  • 2200002D01Rik
  • Stat1
  • stat1
  • stat4
Epitope
AA 1-194, N-Term
97
76
58
27
23
21
19
16
15
15
14
13
7
6
5
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Rat (Rattus)
576
289
233
41
28
27
26
18
16
12
9
9
5
5
4
4
3
3
3
2
1
1
1
Host
Mouse
362
205
20
9
3
3
1
Clonality
Monoclonal
Conjugate
This STAT1 antibody is conjugated to PE
17
16
14
14
14
13
6
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
2
2
1
1
Application
Intracellular Staining (ICS)
504
173
156
102
96
52
52
29
15
13
10
5
5
4
2
1
1
Options
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Catalog No. ABIN1176937
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1176938 ICS Alexa Fluor 647 Mouse IgG1 AA 1-194, N-Term Log in to see 1-Stat1 1

Top referenced anti-STAT1 antibody for Intracellular Staining

Similar anti-STAT1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Chicken Dog (Canine) Frog
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 3 Antibodies 2 Antibodies 1 Antibodies 1 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies
Western Blotting (WB) 477 Antibodies 224 Antibodies 165 Antibodies 15 Antibodies 38 Antibodies 2 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Staining (ICS) 14 Antibodies 14 Antibodies 2 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
Epitope AA 1-194, N-Term
(97), (76), (58), (27), (23), (21), (19), (16), (15), (15), (14), (13), (7), (6), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Frog, Human, Mouse (Murine), Rat (Rattus)
(576), (289), (233), (41), (28), (27), (26), (18), (16), (12), (9), (9), (5), (5), (4), (4), (3), (3), (3), (2), (1), (1), (1)
Host Mouse
(362), (205), (20), (9), (3), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT1 antibody is conjugated to PE
(17), (16), (14), (14), (14), (13), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1)
Application Intracellular Staining (ICS)
(504), (173), (156), (102), (96), (52), (52), (29), (15), (13), (10), (5), (5), (4), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT1 Antibody

Target Details STAT1 Application Details Handling References for anti-STAT1 Antibody (ABIN1176937) Images
Brand BD Phosflow™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human Stat1 aa. 1-194
Clone 1-Stat1
Isotype IgG1

Target Details STAT1

Product Details anti-STAT1 Antibody Application Details Handling References for anti-STAT1 Antibody (ABIN1176937) Images back to top
Antigen
Alternative Name Stat1 (STAT1 Antibody Abstract)
Background Stat (Signal transducer and activators of transcription) proteins are critical mediators of the biologic activity of cytokines, including interleukins, interferons, erythropoietin, and growth factors. Ligand-receptor interaction leads to activation of constitutively associated JAK family kinases and subsequent recruitment/activation of Stat proteins by tyrosine phosphorylation. Active Stat proteins then move to the nucleus to promote transcription of cytokine-inducible genes. Seven Stat proteins have been cloned, each of which is differentially expressed and/or activated in a cytokine-specific and cell type-specific manner. Stat1 and Stat2 are components of the ISGF3 (Interferon-Stimulated Gene Factor 3) complex, which is the primary transcription activator induced by the binding of the interferon to a specific cell-surface receptor. Stat1 has two alternatively spliced isoforms, 91-kDa Stat1alpha and 84 kDa Stat1beta, Stat1alpha has 38 additional C-terminal amino acids. In response to the binding of IFNalpha, IFNgamma, EGF, PDGF, or CSF-1 to their respective receptors, the Stat1 subunits become tyrosine-phosphorylated at Y701, and the complex is translocated to the nucleus. This results in the formation of an active complex that includes the DNA-binding p48 subunit. This complex is responsible for modulating the transcription of the interferon-stimulated genes (ISGs). Thus, phosphorylation of Y701 in Stat1 occurs in response to growth factors and cytokines, and is essential for normal transcriptional activity of the ISGF3 complex. The 1/Stat1 monoclonal antibody recognizes the N-terminus of human Stat1 (both isoforms), regardless of phosphorylation status.
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C

Application Details

Product Details anti-STAT1 Antibody Target Details STAT1 Handling References for anti-STAT1 Antibody (ABIN1176937) Images back to top
Sample Volume 20 μL
Restrictions For Research Use only

Handling

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details References for anti-STAT1 Antibody (ABIN1176937) Images back to top
Format Liquid
Buffer Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References for anti-STAT1 Antibody (ABIN1176937)

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling Images back to top
Product cited in:

Heim: "The Jak-STAT pathway: specific signal transduction from the cell membrane to the nucleus." in: European journal of clinical investigation, Vol. 26, Issue 1, pp. 1-12, 1996

Images

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling References for anti-STAT1 Antibody (ABIN1176937) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-STAT1 antibody (Signal Transducer and Activator of Transcription 1, 91kDa) (AA 1-194) (PE) (ABIN1176937) anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-194), (N-Term) antibody (PE)