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anti-Human STAT1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended STAT1 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
  • 2010005J02Rik
  • AA408197
  • CANDF7
  • DD6G4-4
  • dZ182H3.3
  • H2RSP
  • IMUP
  • IMUP-1
  • IMUP-2
  • ISGF-3
  • si:by51f19.1
  • si:by134g18.2
  • si:dz73o4.2
  • si:dz182h3.3
  • si:dz199m19.1
  • STAT
  • STAT1
  • STAT4
  • STAT91
  • XStat1
Epitope
AA 700-750, pSer727
93
78
70
27
23
20
18
18
13
12
12
11
7
6
5
5
4
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
556
241
178
29
17
16
15
14
7
5
4
3
2
2
2
2
2
2
1
1
Host
Rabbit
369
185
20
6
3
3
1
Clonality
Polyclonal
Conjugate
This STAT1 antibody is un-conjugated
16
15
15
13
13
12
6
6
5
5
5
5
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
495
165
163
91
89
55
32
31
18
15
10
6
5
2
2
1
Supplier
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Catalog No. ABIN746168
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008846439 ABIN876893 IF (p) Alexa Fluor 350 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN876894 IF (p) Alexa Fluor 555 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN876896 IF (p) Alexa Fluor 488 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN876892 IF (p) Alexa Fluor 647 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN746171 IF (p) Cy3 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN746172 IF (p) Cy5 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN746174 IF (p) Cy7 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN746175 IF (p) FITC Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN674889 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008846439 ABIN746173 IF (p) Cy5.5 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN2806698 IF (p) Alexa Fluor 594 Rabbit IgG AA 700-750, pSer727 Log in to see Polyclonal
0.0008846439 ABIN2806696 IF (p) Alexa Fluor 594 Rabbit IgG AA 260-310 Log in to see Polyclonal
0.0008846439 ABIN880054 IF (p) Alexa Fluor 647 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN880055 IF (p) Alexa Fluor 555 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN880056 IF (p) Alexa Fluor 488 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN880058 IF (p) Alexa Fluor 350 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN732627 IF (p) Cy5 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN732628 IF (p) Cy5.5 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN732629 IF (p) Cy7 Rabbit IgG pTyr701 Log in to see Polyclonal
0.0008846439 ABIN732630 IF (p) FITC Rabbit IgG pTyr701 Log in to see Polyclonal

Similar anti-STAT1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
BioImaging (BI) 2 Antibodies 2 Antibodies
ELISA 39 Antibodies 53 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies 7 Antibodies
Immunochromatography (IC) 2 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 18 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 79 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 28 Antibodies
Immunoprecipitation (IP) 34 Antibodies
Intracellular Staining (ICS) 4 Antibodies
Western Blotting (WB) 135 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
Epitope AA 700-750, pSer727
(93), (78), (70), (27), (23), (20), (18), (18), (13), (12), (12), (11), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(556), (241), (178), (29), (17), (16), (15), (14), (7), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(369), (185), (20), (6), (3), (3), (1)
Clonality
Polyclonal
Conjugate This STAT1 antibody is un-conjugated
(16), (15), (15), (13), (13), (12), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(495), (165), (163), (91), (89), (55), (32), (31), (18), (15), (10), (6), (5), (2), (2), (1)
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Product Details anti-STAT1 Antibody

Target Details STAT1 Application Details Handling Images
Specificity This phosphorylation site is homologous across the listed species.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human STAT1 around the phosphorylation site of Ser727
Isotype IgG

Target Details STAT1

Product Details anti-STAT1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Stat1 (STAT1 Antibody Abstract)
Background

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Subcellular location: Cytoplasm, Nucleus


Synonyms: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1
Gene ID 6772
UniProt P42224
Research Area Cancer, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway

Application Details

Product Details anti-STAT1 Antibody Target Details STAT1 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-STAT1 antibody (Signal Transducer and Activator of Transcription 1, 91kDa) (AA 700-750) (ABIN746168) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti phospho-S...