anti-Mouse (Murine) STAT1 antibody for Enzyme Immunoassay

Recommended STAT1 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
  • IMUP
  • H2RSP
  • IMUP-1
  • IMUP-2
  • 2010005J02Rik
  • AA408197
  • DD6G4-4
  • CANDF7
  • ISGF-3
  • STAT91
  • STAT4
  • XStat1
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
  • signal transducer and activator of transcription 1, 91kDa
  • RIKEN cDNA 2200002D01 gene
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 4
  • STAT1
  • 2200002D01Rik
  • Stat1
  • stat1
  • stat4
Epitope
C-Term
108
81
60
27
23
21
19
16
15
15
13
9
8
6
5
5
5
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
617
298
243
43
27
26
26
23
18
15
14
11
9
5
4
4
3
3
2
2
2
1
1
Host
Rabbit
396
209
20
15
3
3
1
Clonality
Polyclonal
Conjugate
This STAT1 antibody is un-conjugated
18
18
15
14
14
14
7
7
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
2
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
539
186
162
112
104
56
52
31
24
14
9
5
5
4
2
2
1
1
1
Supplier
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Catalog No. ABIN401411
$ 419.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5551697 EIA WB Rabbit IgG pTyr701 Log in to see Polyclonal
1 ABIN5555267 EIA IF IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN5611535 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN5611519 EIA IHC (p) WB Rabbit IgG pSer727 Log in to see Polyclonal
1 ABIN318124 EIA IHC (p) IP WB Rabbit pTyr701 Log in to see Polyclonal
1 ABIN2732775 EIA WB Rabbit IgG Log in to see Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
Epitope C-Term
(108), (81), (60), (27), (23), (21), (19), (16), (15), (15), (13), (9), (8), (6), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(617), (298), (243), (43), (27), (26), (26), (23), (18), (15), (14), (11), (9), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(396), (209), (20), (15), (3), (3), (1)
Clonality
Polyclonal
Conjugate This STAT1 antibody is un-conjugated
(18), (18), (15), (14), (14), (14), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(539), (186), (162), (112), (104), (56), (52), (31), (24), (14), (9), (5), (5), (4), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT1 Antibody

Target Details STAT1 Application Details Handling ProductDetails: References for anti-STAT1 antibody (ABIN401411) Images
Specificity This antibody is specific for Stat1 protein.
Cross-Reactivity (Details) Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse.
Purification Affinity chromatography on Protein A
Immunogen Synthetic peptide corresponding to residues near the carboxy terminus of mouse Stat1 protein
Isotype IgG

Target Details STAT1

Product Details anti-STAT1 Antibody Application Details Handling ProductDetails: References for anti-STAT1 antibody (ABIN401411) Images back to top
Antigen
Alternative Name STAT1 (STAT1 Antibody Abstract)
Background Signal transducer and activator of transcription 1 (Stat1) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation of Stat1 at Tyr701 induces Stat1 dimerization, nuclear translocation and DNA binding. Stat1 has two isoforms, Stat1alpha (91 kDa) and the splice variant Stat1beta (84 kDa). Stat1 has been found to be inappropriately activated in many tumors. In addition to tyrosine phosphorylation, Stat1 is phosphorylated through a p38 mitogen-activated protein kinase (MAPK)-dependent pathway at Ser727 in response to IFN-gamma and other cellular stresses. Stat1 is localized in the cytoplasm and upon phosphorylation at Y701 is translocated to the nucleus.Synonyms: Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84
Gene ID 10090
UniProt P42225
Research Area Cancer, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events

Application Details

Product Details anti-STAT1 Antibody Target Details STAT1 Handling ProductDetails: References for anti-STAT1 antibody (ABIN401411) Images back to top
Application Notes ELISA: 1/25,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details ProductDetails: References for anti-STAT1 antibody (ABIN401411) Images back to top
Concentration 2.3 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

ProductDetails: References for anti-STAT1 antibody (ABIN401411)

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling Images back to top
Background publications

Yu, Jove: "The STATs of cancer--new molecular targets come of age." in: Nature reviews. Cancer, Vol. 4, Issue 2, pp. 97-105, 2004