anti-Sheep (Ovine) STAT1 antibody for Immunohistochemistry

Recommended STAT1 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
  • IMUP
  • H2RSP
  • IMUP-1
  • IMUP-2
  • 2010005J02Rik
  • AA408197
  • DD6G4-4
  • CANDF7
  • ISGF-3
  • STAT91
  • STAT4
  • XStat1
  • STAT
  • STAT1
  • dZ182H3.3
  • si:by134g18.2
  • si:by51f19.1
  • si:dz182h3.3
  • si:dz199m19.1
  • si:dz73o4.2
  • signal transducer and activator of transcription 1, 91kDa
  • RIKEN cDNA 2200002D01 gene
  • signal transducer and activator of transcription 1
  • signal transducer and activator of transcription 4
  • STAT1
  • 2200002D01Rik
  • Stat1
  • stat1
  • stat4
Epitope
N-Term
108
81
61
27
23
21
19
16
15
15
13
8
8
6
5
5
5
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish
617
298
243
42
26
26
26
22
17
14
14
10
9
5
4
4
3
3
2
2
1
1
1
Host
Rabbit
396
209
20
15
3
3
1
Clonality
Polyclonal
Conjugate
This STAT1 antibody is un-conjugated
18
18
15
14
14
14
7
7
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
2
2
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
539
185
162
112
104
56
52
31
24
14
10
5
5
4
2
2
1
1
1
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Catalog No. ABIN2780843
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.895042 ABIN2469995 IP IHC WB Mouse IgG2b AA 721-733 Log in to see SM1
8.895042 ABIN2957762 IC IF IP IHC WB Rabbit C-Term, pTyr701 Log in to see Polyclonal
8.895042 ABIN2705255 IP IHC WB Rabbit C-Term Log in to see Polyclonal
8.895042 ABIN2705254 IC IF IP IHC WB Rabbit C-Term, pSer727 Log in to see Polyclonal
1 ABIN2780844 IHC WB Rabbit C-Term Log in to see Polyclonal 1
1 ABIN2994849 IF/ICC IHC IP WB Rabbit pSer727 Log in to see Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antibodies
Epitope N-Term
(108), (81), (61), (27), (23), (21), (19), (16), (15), (15), (13), (8), (8), (6), (5), (5), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Zebrafish
(617), (298), (243), (42), (26), (26), (26), (22), (17), (14), (14), (10), (9), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(396), (209), (20), (15), (3), (3), (1)
Clonality
Polyclonal
Conjugate This STAT1 antibody is un-conjugated
(18), (18), (15), (14), (14), (14), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(539), (185), (162), (112), (104), (56), (52), (31), (24), (14), (10), (5), (5), (4), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-STAT1 Antibody

Target Details STAT1 Application Details Handling ProductDetails: References for anti-STAT1 antibody (ABIN2780843) Images
Blocking Peptide Blocking peptide for this product available: ABIN984525
Sequence MSQWYELQQL DSKFLEQVHQ LYDDSFPMEI RQYLAQWLEK QDWEHAANDV
Predicted Reactivity Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 86%
Characteristics This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human STAT1

Target Details STAT1

Product Details anti-STAT1 Antibody Application Details Handling ProductDetails: References for anti-STAT1 antibody (ABIN2780843) Images back to top
Antigen
Alternative Name STAT1 (STAT1 Antibody Abstract)
Background STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: DKFZp686B04100, ISGF-3, STAT91, CANDF7
Protein Interaction Partner: HUWE1, ISG15, PIAS1, UBC, STAT1, EIF1AD, OTUD4, LMO2, GNB2, DTX3L, EGFR, NAA15, SNX6, CAND1, VPS29, GSPT2, JMJD6, RTF1, HSPA4L, ATG7, YAP1, PAWR, KARS, IDE, CTTN, VPS26A, HIRIP3, NAA10, TSNAX, TBCD, SNX2, SNX1, SHMT2, SHMT1, SARS, ATP6V1C1, APEH, USP13, E
Protein Size: 750
Molecular Weight 87 kDa
Gene ID 6772
NCBI Accession NM_007315, NP_009330
UniProt P42224
Research Area Cancer, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events

Application Details

Product Details anti-STAT1 Antibody Target Details STAT1 Handling ProductDetails: References for anti-STAT1 antibody (ABIN2780843) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 750 AA

Restrictions For Research Use only

Handling

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details ProductDetails: References for anti-STAT1 antibody (ABIN2780843) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-STAT1 antibody (ABIN2780843)

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling Images back to top
Product cited in:

Deng, Chen, Li, Yuan, Li, Ke, Wang, Wu, Luo: "Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10555-64, 2015

Background publications

Battle, Lynch, Frank: "Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis." in: Cancer research, Vol. 66, Issue 7, pp. 3649-57, 2006

Images

Product Details anti-STAT1 Antibody Target Details STAT1 Application Details Handling ProductDetails: References for anti-STAT1 antibody (ABIN2780843) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (N-Term) antibody (ABIN2780843) anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (N-Term) antibody