Browse our anti-STAT3 (STAT3) Antibodies

On www.antibodies-online.com are 637 Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies from 41 different suppliers available. Additionally we are shipping STAT3 Kits (62) and STAT3 Proteins (34) and many more products for this protein. A total of 761 STAT3 products are currently listed.
Synonyms:
1110034C02Rik, aprf, AW109958, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3
list all antibodies Gene Name GeneID UniProt
STAT3 20848 P42227
STAT3 6774 P40763
STAT3 25125 P52631

Most Popular Reactivities for anti-STAT3 (STAT3) Antibodies

anti-Mouse (Murine) STAT3 Antibodies:

anti-Human STAT3 Antibodies:

anti-Rat (Rattus) STAT3 Antibodies:

All available anti-STAT3 Antibodies

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More Antibodies against STAT3 Interaction Partners

Mouse (Murine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. The results suggest that biochanin A activates RORgamma-dependent IL-17 (show IL17A Antibodies) transcription through the enhancement of STAT3 phosphorylation and STAT3-mediated recruitment of NCOA1 (show NCOA1 Antibodies) to RORgamma.

  2. Loss of Sav1 (show SAV1 Antibodies) induced Stat3 activation and a senescence-associated secretory phenotype (SASP (show ASPRV1 Antibodies)) that coincided with the development of tubulointerstitial fibrosis.

  3. this study shows that STAT3-deficient Th9 cells have increased IL-9 (show IL9 Antibodies) production that is maintained for longer in culture than IL-9 (show IL9 Antibodies) in control cultures

  4. myeloid-specific Stat3 deletion causes defects in multiple aspects of the immune system

  5. LIF (show LIF Antibodies)/STAT3 and MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) signaling in naive embryonic stem cell pluripotency, is reported.

  6. apoA-I (show APOA1 Antibodies)/ABCA1 (show ABCA1 Antibodies)-mediated cholesterol efflux without STAT3 activation can reduce proinflammatory cytokine expression in macrophages.

  7. IL-6 (show IL6 Antibodies) can directly induce the transition of HSCs toward myofibroblast-like cells. The effect is mediated by the activation of both MAPK (show MAPK1 Antibodies) and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling pathways. Elimination of either MAPK (show MAPK1 Antibodies) or JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling pathways inhibits HSC (show FUT1 Antibodies) stimulation

  8. These findings also identify STAT3 as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha (show IFNA Antibodies) responsiveness.

  9. As a result of Tumour-associated macrophages (TAMs)-induced activation of the STAT3 pathway, murine 5T33MM cells are sensitized to AZD1480 treatment.

  10. Stat3-mediated regulation of expression of members of the calcium-activated chloride channel (show CLCA4 Antibodies) regulator (show CLNS1A Antibodies) (CLCA) family of proteins during involution and mammary carcinogenesis.

Human Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Activated STAT3 upregulates the expression of GPx1 (show GPX1 Antibodies) and SOD2 (show SOD2 Antibodies), which reduce the intracellular ROS (show ROS1 Antibodies) levels in Burkitt lymphoma.

  2. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 (show IL6 Antibodies) promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2 (show JAK2 Antibodies)/STAT3 signaling pathway.

  3. Data suggest that C-terminal truncated hepatitis B virus X protein (HBx-DeltaC1) enhances liver cancer stem cell (CSC) properties through Stat3/Nanog (show NANOG Antibodies) cascade, and insight for the therapeutic intervention for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC (show FAM126A Antibodies)).

  4. High STAT3 expression is associated with Hepatocellular Carcinoma.

  5. Phosphorylation of STAT3 was decreased in NRDC (show NRD1 Antibodies)-depleted Huh-7 spheroids.

  6. Mutation inactivating STAT3 gene is associated with Breast Cancer Metastasis.

  7. The activation of NF-kappaB (show NFKB1 Antibodies) and STAT3 signalling-dependent pro-inflammatory cytokine expression.

  8. High STAT3 expression is associated with glioblastomas.

  9. High STAT3 expression is associated with nasopharyngeal cancer.

  10. In this review, we focus on the reciprocal regulation and roles of microRNAs and signal transducer and activator of transcription 3 in cancer, as well as describe current research progress on this relationship. A better understanding of this relationship may facilitate in the identification of targets for clinical therapeutics.

Cow (Bovine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.

  2. Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate

  3. results show for the first time that interleukin-6 (show IL6 Antibodies) (IL), in the presence of its soluble receptor (show IFNAR1 Antibodies) (sIL (show STIL Antibodies)-6R), induces activation of JAK1 (show JAK1 Antibodies), JAK2 (show JAK2 Antibodies), and STAT1 (show STAT1 Antibodies)/STAT3 proteins in bovine articular chondrocytes

  4. peroxynitrite causes increased expression of VEGF (show VEGFA Antibodies) in vascular endothelial cells by a process that requires the activation of STAT3

  5. Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (show NOX1 Antibodies)-mediated activation of STAT3.

Pig (Porcine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets

  2. maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (show CCND2 Antibodies) and PSEN1 (show PSEN1 Antibodies) genes via a STAT3-dependent pathway

  3. Studied effect of recombinant porcine leukemia inhibitory factor (show LIF Antibodies) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 Antibodies)-supplemented media.

  4. Data suggest that IL-6 (interleukin 6 (show IL6 Antibodies)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (show IL6 Antibodies)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).

  5. the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.

  6. Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.

  7. STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways

  8. Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.

Rabbit Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. This is the first report of the genetic polymorphisms of the JAK1 (show JAK1 Antibodies) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.

Guinea Pig Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.

  2. Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (show MMP2 Antibodies) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.

Zebrafish Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Stat3 regulates cell proliferation and axis extension in part via upregulation of Cdc25a (show CDC25A Antibodies) expression during oogenesis. Accordingly, restoring Cdc25a (show CDC25A Antibodies) expression in stat3 mutants partially suppressed cell proliferation and gastrulation defects.

  2. PTPN9 (show PTPN9 Antibodies) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (show GATA1 Antibodies) and ZBP-89 (show ZNF148 Antibodies).

  3. Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.

  4. Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.

  5. This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.

  6. The results of this study suggested that the stat3/socs3 (show SOCS3 Antibodies) pathway is a key response in all tissue regeneration in zebrafish.

  7. stat3, a known oncogene (show RAB1A Antibodies) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.

  8. Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (show PRCP Antibodies) in neighboring cells during zebrafish gastrulation.

STAT3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT3

  • signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3) antibody
  • signal transduction and activation of transcription 3 (stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) antibody
  • signal transducer and activator of transcription 3 (Stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1 (stat3.1) antibody
  • 1110034C02Rik antibody
  • aprf antibody
  • AW109958 antibody
  • hies antibody
  • stat3 antibody
  • wu:fc15d02 antibody
  • wu:fl59g06 antibody
  • Xstat3 antibody
  • z-Stat3 antibody

Protein level used designations for STAT3

signal transducer and activator of transcription 3 (acute-phase response factor) , signal transducer and activator of transcription 3 , signal transduction and activation of transcription 3 , Signal transducer and activator of transcription 3 , signal transducer and activator of transcription 3-like , acute phase response factor , acute-phase response factor , DNA-binding protein APRF , Protein Stat3 , signal transducer and activator of transcription 3.1 , stat 3

GENE ID SPECIES
100011382 Monodelphis domestica
100171541 Pongo abelii
100380714 Salmo salar
100469938 Ailuropoda melanoleuca
100566559 Anolis carolinensis
100598877 Nomascus leucogenys
20848 Mus musculus
6774 Homo sapiens
25125 Rattus norvegicus
490967 Canis lupus familiaris
508541 Bos taurus
733648 Sus scrofa
420027 Gallus gallus
574128 Macaca mulatta
454682 Pan troglodytes
100348778 Oryctolagus cuniculus
100717084 Cavia porcellus
100294659 Ovis aries
779100 Xenopus laevis
30767 Danio rerio
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