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Browse our anti-STAT3 (STAT3) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) Antibodies (STAT3)
On www.antibodies-online.com are 606 Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies from 41 different suppliers available. Additionally we are shipping STAT3 Kits (58) and STAT3 Proteins (25) and many more products for this protein. A total of 718 STAT3 products are currently listed.
Synonyms:
1110034C02Rik, aprf, AW109958, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3
list all antibodies Gene Name GeneID UniProt
STAT3 20848 P42227
STAT3 6774 P40763
STAT3 25125 P52631

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Top referenced anti-STAT3 Antibodies

  1. Human Polyclonal STAT3 Primary Antibody for IHC (p), WB - ABIN389665 : Schick, Oakeley, Hynes, Badache: TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity. in The Journal of biological chemistry 2004 (PubMed)
    Show all 8 references for ABIN389665

  2. Human Polyclonal STAT3 Primary Antibody for EIA, IHC (p) - ABIN358234 : Wang, Wang, Zhang, Huang, Liao, Fuller: Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas. in Laboratory investigation; a journal of technical methods and pathology 2004 (PubMed)
    Show all 5 references for ABIN358234

  3. Human Polyclonal STAT3 Primary Antibody for EIA, IHC (p) - ABIN358233 : Kato, Sakamoto, Kutsuna, Kimura-Eto, Hato, Kitagawa: Proteolytic conversion of STAT3alpha to STAT3gamma in human neutrophils: role of granule-derived serine proteases. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358233

  4. Cow (Bovine) Polyclonal STAT3 Primary Antibody for IHC, WB - ABIN2792239 : Ohbayashi, Kawakami, Muromoto, Togi, Ikeda, Kamitani, Sekine, Honjoh, Matsuda: The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN2792239

  5. Chicken Polyclonal STAT3 Primary Antibody for IF, IHC - ABIN2780479 : Deng, Chen, Li, Liu, Niu, Zhou, Li, Ke, Mo et al.: Bone marrow mesenchymal stromal cells with support of bispecific antibody and ultrasound-mediated microbubbles prevent myocardial fibrosis via the signal transducer and activators of transcription ... in Cytotherapy 2011 (PubMed)
    Show all 2 references for ABIN2780479

  6. Human Polyclonal STAT3 Primary Antibody for IHC, ELISA - ABIN1531975 : Catlett-Falcone, Landowski, Oshiro, Turkson, Levitzki, Savino, Ciliberto, Moscinski, Fernández-Luna, Nuñez, Dalton, Jove: Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. in Immunity 1999 (PubMed)

  7. Human Monoclonal STAT3 Primary Antibody for WB - ABIN1449165 : Yamashita, Miyagi, Carmany-Rampey, Shimizu, Fujii, Schier, Hirano: Stat3 Controls Cell Movements during Zebrafish Gastrulation. in Developmental cell 2002 (PubMed)

  8. Cow (Bovine) Polyclonal STAT3 Primary Antibody for EIA, IF - ABIN374087 : Bromberg, Wrzeszczynska, Devgan, Zhao, Pestell, Albanese, Darnell: Stat3 as an oncogene. in Cell 1999 (PubMed)

  9. Dog (Canine) Polyclonal STAT3 Primary Antibody for WB - ABIN782995 : Palmqvist, Glover, Hsu, Lu, Bossen, Piret, Humphries, Helgason: Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. in Stem cells (Dayton, Ohio) 2005 (PubMed)

More Antibodies against STAT3 Interaction Partners

Mouse (Murine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. These results establish that Bcl3 (show BCL3 Antibodies) positively regulates pluripotency genes and thus shed light on the mechanism of Bcl3 (show BCL3 Antibodies) as a downstream molecule of LIF (show LIF Antibodies)/STAT3 signaling in pluripotency maintenance.

  2. Epo (show EPO Antibodies) regulates hypothalamus POMC (show POMC Antibodies) expression via STAT3 activation.

  3. Findings suggest that isoflurane-induced neurotoxicity may stem from signal transducer and activator of transcription (show STAT1 Antibodies)- degradation, partially through the activation of calcineurin (show PPP3CA Antibodies).

  4. Antisense oligonucleotide AZD9150 decreased STAT3 expression in a broad range of preclinical cancer models and showed antitumor activity in lymphoma and lung cancer models.

  5. STAT1 (show STAT1 Antibodies) deficiency reprograms IFN signaling from priming toward suppression of TLR response via feedback regulation of STAT3.

  6. These data support a role of pSTAT3 in TLR4 (show TLR4 Antibodies) dependent Abdominal Aortic Aneurysm (AAA (show AAAS Antibodies)) formation and possible therapeutic roles for TLR4 (show TLR4 Antibodies) and/or STAT3 inhibition in AAA (show AAAS Antibodies)

  7. the expression changes observed within the BCL2 (show BCL2 Antibodies) family did not depend on STAT3 signalling, in line with its initiating role early in the process, but rather appear to result from relief of repression by STAT5 (show STAT5A Antibodies).

  8. Sphingosylphosphorylcholine promotes the differentiation of resident Sca-1 (show Ly6a Antibodies) positive cardiac stem cells to cardiomyocytes through lipid raft/JNK (show MAPK8 Antibodies)/STAT3 and beta-catenin (show CTNNB1 Antibodies) signaling pathways.

  9. CCR5 (show CCR5 Antibodies) blockade suppresses B16 melanoma growth by inhibiting of IL-6 (show IL6 Antibodies)-Stat3 signaling pathway via upregulation of SOCS3 (show SOCS3 Antibodies).

  10. neuronal and astroglial STAT3 molecules are involved in the pathways underlying cell death

Human Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. The STAT3-Ser (show SIGLEC1 Antibodies)/Hes3 (show HES3 Antibodies) Signaling Axis was first identified as a major regulator of neural stem cells and, subsequently, cancer stem cells

  2. our data suggest that SIRT6 (show SIRT6 Antibodies) suppresses glioma cell growth via induction of apoptosis, inhibition of oxidative stress and inhibition of the activation of the JAK2 (show JAK2 Antibodies)/STAT3 signaling pathway.

  3. this study shows that miR (show MLXIP Antibodies)-124-3p may negatively regulate the transcription of the STAT3 by interfering with its 3'UTR (show UTS2R Antibodies), and the degradation of STAT3 affects its downstream expression of such as p-STAT3, CCND2 (show CCND2 Antibodies) and MMP-2 (show MMP2 Antibodies)

  4. Our data suggested that IL-6 (show IL6 Antibodies) mediates the singnal pathway of JAK (show JAK3 Antibodies)-STAT3-VEGF-C (show VEGFC Antibodies) promoting the growth, invasion and lymphangiogenesis in gastric cancer

  5. Treatment of isolinderalactone increased the protein level of SCOS3, decreased phosphorylation of the STAT3 and suppressed expression of the down-stream genes of the X-linked inhibitor of apoptosis protein (show XIAP Antibodies)

  6. The rs4796793 STAT3 genotype is a novel predictive factor for response to multiple tyrosine kinase (show TXK Antibodies) inhibitors in metastatic renal cell carcinoma (show MOK Antibodies).

  7. the STAT3 mutations found in the patient cohort were concluded to be deleterious for normal STAT3 function.

  8. Our data indicated that Eag1 promotes osteosarcoma proliferation and migration, at least in part, by targeting STAT3-VEGF pathway.

  9. STAT3 is a direct target of miR (show MLXIP Antibodies)-506. STAT3 mRNA expression was increased in glioma and inversely correlated with miR (show MLXIP Antibodies)-506. Its overexpression attenuated the suppressive effects of miR (show MLXIP Antibodies)-506 on cell proliferation, colony formation, migration and invasion.

  10. The present study finds that the aspirin-FOXD3 (show FOXD3 Antibodies)-OLA1P2-STAT3 axis exhibits exciting anticancer effects and provides new insights into the chemopreventive mechanisms underlying aspirin use

Cow (Bovine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.

  2. Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate

  3. results show for the first time that interleukin-6 (show IL6 Antibodies) (IL), in the presence of its soluble receptor (show IFNAR1 Antibodies) (sIL (show STIL Antibodies)-6R), induces activation of JAK1 (show JAK1 Antibodies), JAK2 (show JAK2 Antibodies), and STAT1 (show STAT1 Antibodies)/STAT3 proteins in bovine articular chondrocytes

  4. peroxynitrite causes increased expression of VEGF (show VEGFA Antibodies) in vascular endothelial cells by a process that requires the activation of STAT3

  5. Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (show NOX1 Antibodies)-mediated activation of STAT3.

Pig (Porcine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Studied effect of recombinant porcine leukemia inhibitory factor (show LIF Antibodies) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 Antibodies)-supplemented media.

  2. Data suggest that IL-6 (interleukin 6 (show IL6 Antibodies)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (show IL6 Antibodies)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).

  3. the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.

  4. Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.

  5. STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways

  6. Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.

Rabbit Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. This is the first report of the genetic polymorphisms of the JAK1 (show JAK1 Antibodies) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.

Guinea Pig Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.

  2. Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (show MMP2 Antibodies) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.

Zebrafish Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. PTPN9 (show PTPN9 Antibodies) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (show GATA1 Antibodies) and ZBP-89 (show ZNF148 Antibodies).

  2. Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.

  3. Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.

  4. This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.

  5. The results of this study suggested that the stat3/socs3 (show SOCS3 Antibodies) pathway is a key response in all tissue regeneration in zebrafish.

  6. stat3, a known oncogene (show RAB1A Antibodies) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.

  7. Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (show PRCP Antibodies) in neighboring cells during zebrafish gastrulation.

STAT3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT3

  • signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3) antibody
  • signal transduction and activation of transcription 3 (stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) antibody
  • signal transducer and activator of transcription 3 (Stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1 (stat3.1) antibody
  • 1110034C02Rik antibody
  • aprf antibody
  • AW109958 antibody
  • hies antibody
  • stat3 antibody
  • wu:fc15d02 antibody
  • wu:fl59g06 antibody
  • Xstat3 antibody
  • z-Stat3 antibody

Protein level used designations for STAT3

signal transducer and activator of transcription 3 (acute-phase response factor) , signal transducer and activator of transcription 3 , signal transduction and activation of transcription 3 , Signal transducer and activator of transcription 3 , signal transducer and activator of transcription 3-like , acute phase response factor , acute-phase response factor , DNA-binding protein APRF , Protein Stat3 , signal transducer and activator of transcription 3.1 , stat 3

GENE ID SPECIES
100011382 Monodelphis domestica
100171541 Pongo abelii
100380714 Salmo salar
100469938 Ailuropoda melanoleuca
100566559 Anolis carolinensis
100598877 Nomascus leucogenys
20848 Mus musculus
6774 Homo sapiens
25125 Rattus norvegicus
490967 Canis lupus familiaris
508541 Bos taurus
733648 Sus scrofa
420027 Gallus gallus
574128 Macaca mulatta
454682 Pan troglodytes
100348778 Oryctolagus cuniculus
100717084 Cavia porcellus
100294659 Ovis aries
779100 Xenopus laevis
30767 Danio rerio
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