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Browse our anti-STAT3 (STAT3) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) Antibodies (STAT3)
On www.antibodies-online.com are 592 Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies from 41 different suppliers available. Additionally we are shipping STAT3 Kits (58) and STAT3 Proteins (25) and many more products for this protein. A total of 708 STAT3 products are currently listed.
Synonyms:
1110034C02Rik, aprf, AW109958, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3
list all antibodies Gene Name GeneID UniProt
STAT3 20848 P42227
STAT3 6774 P40763
STAT3 25125 P52631

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Top referenced anti-STAT3 Antibodies

  1. Human Polyclonal STAT3 Primary Antibody for EIA, IHC (p) - ABIN358233 : Schick, Oakeley, Hynes, Badache: TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358233

  2. Human Polyclonal STAT3 Primary Antibody for EIA, IHC (p) - ABIN358234 : Wang, Wang, Zhang, Huang, Liao, Fuller: Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas. in Laboratory investigation; a journal of technical methods and pathology 2004 (PubMed)
    Show all 5 references for ABIN358234

  3. Cow (Bovine) Polyclonal STAT3 Primary Antibody for IHC, WB - ABIN2792239 : Ohbayashi, Kawakami, Muromoto, Togi, Ikeda, Kamitani, Sekine, Honjoh, Matsuda: The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN2792239

  4. Chicken Polyclonal STAT3 Primary Antibody for IF, IHC - ABIN2780479 : Deng, Chen, Li, Liu, Niu, Zhou, Li, Ke, Mo et al.: Bone marrow mesenchymal stromal cells with support of bispecific antibody and ultrasound-mediated microbubbles prevent myocardial fibrosis via the signal transducer and activators of transcription ... in Cytotherapy 2011 (PubMed)
    Show all 2 references for ABIN2780479

  5. Human Monoclonal STAT3 Primary Antibody for WB - ABIN1449165 : Yamashita, Miyagi, Carmany-Rampey, Shimizu, Fujii, Schier, Hirano: Stat3 Controls Cell Movements during Zebrafish Gastrulation. in Developmental cell 2002 (PubMed)

  6. Human Polyclonal STAT3 Primary Antibody for ELISA, WB - ABIN185692 : Palmqvist, Glover, Hsu, Lu, Bossen, Piret, Humphries, Helgason: Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. in Stem cells (Dayton, Ohio) 2005 (PubMed)

  7. Cow (Bovine) Polyclonal STAT3 Primary Antibody for EIA, IF - ABIN374087 : Bromberg, Wrzeszczynska, Devgan, Zhao, Pestell, Albanese, Darnell: Stat3 as an oncogene. in Cell 1999 (PubMed)

  8. Human Polyclonal STAT3 Primary Antibody for IHC, ELISA - ABIN1531975 : Catlett-Falcone, Landowski, Oshiro, Turkson, Levitzki, Savino, Ciliberto, Moscinski, Fernández-Luna, Nuñez, Dalton, Jove: Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. in Immunity 1999 (PubMed)

More Antibodies against STAT3 Interaction Partners

Mouse (Murine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. CCR5 (show CCR5 Antibodies) blockade suppresses B16 melanoma growth by inhibiting of IL-6 (show IL6 Antibodies)-Stat3 signaling pathway via upregulation of SOCS3 (show SOCS3 Antibodies).

  2. neuronal and astroglial STAT3 molecules are involved in the pathways underlying cell death

  3. STAT3 functions as a negative regulator of IL-9 (show IL9 Antibodies) production through attenuation of STAT5 (show STAT5A Antibodies) activation and function.

  4. T cell-intrinsic role of Arid5a (show ARID5A Antibodies) on fate decisions of naive CD4 (show CD4 Antibodies)(+)T cells through selective stabilization of Stat3 mRNA.

  5. UT2 is a negative regulator shared across STAT3 and mTORC2 (show CRTC2 Antibodies) signaling cascades, functioning as a tumor suppressor in hematologic malignancies driven by those pathways.

  6. this study demonstrated a critical role of zinc in the pluripotency maintenance of mouse ES cells, as well as an important regulator of Stat3 signaling.

  7. KPNB1 (show KPNB1 Antibodies) may play a key role in the inflammation process of rheumatoid arthritis via STAT3 signal transduction pathway.

  8. The liver regenerative effects of HCM appear to be mediated by persistent and uninhibited expression of STAT3 in the liver, which results from decreased expression of SOCS3 (show SOCS3 Antibodies)

  9. Dynamic control of Th2 cell responses by STAT3 during allergic lung inflammation in mice

  10. Stat3-deficient mice initially formed hyperplastic and early adenoma-like lesions.

Human Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. found STAT3 could bind promoter region of TXNDC17 (show TXNDC17 Antibodies) (-623 bp to -58 bp relative to the transcription start site (TSS (show RPL38 Antibodies))) for regulating its expression

  2. this study proposes that inflammation-induced Jak (show JAK3 Antibodies)-STAT3 signaling leads to colon cancer development through proteasomal degradation of DICER1 (show DICER1 Antibodies) by ubiquitin ligase complex of CUL4A (show CUL4A Antibodies)(DCAF1 (show VPRBP Antibodies)), which suggests a novel therapeutic opportunity for colon cancer

  3. STAT3 and miR (show MLXIP Antibodies)-21 are cooperative regulators of stemness, migration and tumor initiation in lung-derived brain metastasis

  4. Our results suggest the significance of STAT3 activation in the maintenance and survival of ovarian cancer cells

  5. miR (show MLXIP Antibodies)-125a-5p directly targets IL-6R and STAT3 expression in HEK (show EPHA3 Antibodies)-293T cells.

  6. in patients with hyper-IgE syndrome, mutations lead to impaired Th17 cell numbers

  7. The human monocytes are predisposed to differentiate towards an macrophage activation program characterized by the CD16 (show CD16 Antibodies)(+)CD163 (show CD163 Antibodies)(+)MerTK (show MERTK Antibodies)(+)pSTAT3(+) phenotype and functional properties such as enhanced protease-dependent motility, and immunomodulation.

  8. UT2 (show SLC14A2 Antibodies) is a negative regulator shared across STAT3 and mTORC2 (show CRTC2 Antibodies) signaling cascades, functioning as a tumor suppressor in hematologic malignancies driven by those pathways.

  9. The endometrium of women with dormant genital tuberculosis is associated with poor receptivity, as evidenced by aberrant LIF (show LIF Antibodies)-STAT3 signaling.

  10. potential utility of a signature involving Bcl-2 (show BCL2 Antibodies) overexpression, Rac1 activation and STAT3 phosphorylation for stratifying clinical lymphomas based on disease severity and chemoresistance

Cow (Bovine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.

  2. Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate

  3. results show for the first time that interleukin-6 (show IL6 Antibodies) (IL), in the presence of its soluble receptor (show IFNAR1 Antibodies) (sIL (show STIL Antibodies)-6R), induces activation of JAK1 (show JAK1 Antibodies), JAK2 (show JAK2 Antibodies), and STAT1 (show STAT1 Antibodies)/STAT3 proteins in bovine articular chondrocytes

  4. peroxynitrite causes increased expression of VEGF (show VEGFA Antibodies) in vascular endothelial cells by a process that requires the activation of STAT3

  5. Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (show NOX1 Antibodies)-mediated activation of STAT3.

Pig (Porcine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Studied effect of recombinant porcine leukemia inhibitory factor (show LIF Antibodies) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 Antibodies)-supplemented media.

  2. Data suggest that IL-6 (interleukin 6 (show IL6 Antibodies)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (show IL6 Antibodies)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).

  3. the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.

  4. Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.

  5. STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways

  6. Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.

Rabbit Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. This is the first report of the genetic polymorphisms of the JAK1 (show JAK1 Antibodies) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.

Guinea Pig Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.

  2. Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (show MMP2 Antibodies) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.

Zebrafish Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. PTPN9 (show PTPN9 Antibodies) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (show GATA1 Antibodies) and ZBP-89 (show ZNF148 Antibodies).

  2. Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.

  3. Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.

  4. This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.

  5. The results of this study suggested that the stat3/socs3 (show SOCS3 Antibodies) pathway is a key response in all tissue regeneration in zebrafish.

  6. stat3, a known oncogene (show RAB1A Antibodies) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.

  7. Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (show PRCP Antibodies) in neighboring cells during zebrafish gastrulation.

STAT3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT3

  • signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3) antibody
  • signal transduction and activation of transcription 3 (stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) antibody
  • signal transducer and activator of transcription 3 (Stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3) antibody
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1 (stat3.1) antibody
  • 1110034C02Rik antibody
  • aprf antibody
  • AW109958 antibody
  • hies antibody
  • stat3 antibody
  • wu:fc15d02 antibody
  • wu:fl59g06 antibody
  • Xstat3 antibody
  • z-Stat3 antibody

Protein level used designations for STAT3

signal transducer and activator of transcription 3 (acute-phase response factor) , signal transducer and activator of transcription 3 , signal transduction and activation of transcription 3 , Signal transducer and activator of transcription 3 , signal transducer and activator of transcription 3-like , acute phase response factor , acute-phase response factor , DNA-binding protein APRF , Protein Stat3 , signal transducer and activator of transcription 3.1 , stat 3

GENE ID SPECIES
100011382 Monodelphis domestica
100171541 Pongo abelii
100380714 Salmo salar
100469938 Ailuropoda melanoleuca
100566559 Anolis carolinensis
100598877 Nomascus leucogenys
20848 Mus musculus
6774 Homo sapiens
25125 Rattus norvegicus
490967 Canis lupus familiaris
508541 Bos taurus
733648 Sus scrofa
420027 Gallus gallus
574128 Macaca mulatta
454682 Pan troglodytes
100348778 Oryctolagus cuniculus
100717084 Cavia porcellus
100294659 Ovis aries
779100 Xenopus laevis
30767 Danio rerio
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