anti-Dog (Canine) STAT3 antibody for Enzyme Immunoassay

Recommended STAT3 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
  • 1110034C02Rik
  • AW109958
  • Aprf
  • APRF
  • HIES
  • Xstat3
  • aprf
  • hies
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • z-Stat3
  • signal transducer and activator of transcription 3 (acute-phase response factor)
  • signal transduction and activation of transcription 3
  • signal transducer and activator of transcription 3
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1
  • STAT3
  • stat3
  • Stat3
  • stat3.1
Epitope
C-Term, Isoform 1
127
107
74
28
18
17
16
16
15
13
11
6
6
6
5
5
5
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
623
364
286
39
37
32
29
16
11
10
7
5
5
5
4
3
3
2
1
1
1
1
1
Host
Goat
480
149
33
6
2
1
Clonality
Polyclonal
Conjugate
This STAT3 antibody is un-conjugated
28
24
20
14
12
11
10
7
5
5
5
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
561
244
229
93
87
84
74
59
27
12
11
9
8
6
5
4
3
3
3
2
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN5552647
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN126898 EIA IHC (fro) IF IP WB Mouse IgG1 pTyr705 Log in to see 9-00E-012
1 ABIN126899 EIA IHC (fro) WB Mouse IgG1 phosphorylated Log in to see 23G5
1 ABIN126896 EIA IHC (fro) IF IP WB Biotin Mouse IgG1 pTyr705 Log in to see 9-00E-012
1 ABIN1109150 EIA WB Rabbit IgG C-Term Log in to see Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
Epitope C-Term, Isoform 1
(127), (107), (74), (28), (18), (17), (16), (16), (15), (13), (11), (6), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(623), (364), (286), (39), (37), (32), (29), (16), (11), (10), (7), (5), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1)
Host Goat
(480), (149), (33), (6), (2), (1)
Clonality
Polyclonal
Conjugate This STAT3 antibody is un-conjugated
(28), (24), (20), (14), (12), (11), (10), (7), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(561), (244), (229), (93), (87), (84), (74), (59), (27), (12), (11), (9), (8), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
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Product Details anti-STAT3 Antibody

Target Details STAT3 Application Details Handling Images
Sequence DMELTSECAT SPM
Specificity This antibody is expected to recognize Isoform 1 (NP_644805.1) and Isoform 2 (NP_003141.2).
Cross-Reactivity (Details) Species reactivity (expected):Canine (Dog), Pig and Bovine.
Species reactivity (tested):Human, Mouse, Rat.
Purification Immunoaffinity Chromatography
Immunogen Peptide from C-Terminus of the protein sequence according to NP_003141.2, NP_644805.1. Genename: STAT3

Target Details STAT3

Product Details anti-STAT3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name STAT3 (STAT3 Antibody Abstract)
Background The STAT3 protein is expressed in most cell types and is activated by multiple cytokines and growth factors including: IFNa, IL10, IL6, IL11, IL12, IL2, EGF, among others. STAT3 beta appears to be activated by both EGF and IL6, but STAT3 alpha is only activated by EGF. STAT3 binds to DNA as either a homodimer or as a heterodimer with STAT1. STAT3 interacts with the APRE acute phase response element) and SIE (csis inducible element). STAT4, predominantly expressed in testis and myeloid cells, is activated by ILl2. STAT5 is activated by prolactin and IL3. STAT6 participates in signaling pathways mediated by IL4.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
Gene ID 6774
NCBI Accession NP_003141
UniProt P40763
Research Area Embryogenesis, Embryonic stem cells, Inflammation, Receptors, Signaling, Transcription Factors
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-STAT3 Antibody Target Details STAT3 Handling Images back to top
Application Notes Peptide ELISA: 1/128000. Western blot: 1-3 μg/mL. Approx.90 kDa band observed in lysates of NIH3T3 (calculatedMW of 88.0 kDa according to NP_644805.1 and of 88.1 according to NP_003141.2). Immunohistochemistry: Rommended overnight staining at 10 μg/mL (See picture). Stainsmouse thymic medulla and not the cortex.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.