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anti-Monkey STAT3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended STAT3 Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
  • 1110034C02Rik
  • APRF
  • Aprf
  • aprf
  • AW109958
  • hies
  • HIES
  • stat3
  • wu:fc15d02
  • wu:fl59g06
  • Xstat3
  • z-Stat3
Reactivity
Human, Monkey, Mouse (Murine)
544
265
208
30
24
24
12
11
10
5
4
3
3
2
2
2
2
1
1
1
1
1
Host
Mouse
466
108
34
4
1
1
Clonality
Monoclonal
Conjugate
This STAT3 antibody is un-conjugated
24
22
18
13
12
11
8
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
502
238
216
79
74
70
52
32
23
13
12
11
9
7
3
3
2
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN1109152
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008985052 ABIN4356377 ChIP ICC IF IHC IHC (p) IP WB Mouse IgG Log in to see 9D8

Top referenced anti-STAT3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-STAT3 Antibodies

Application / Reactivity Mouse (Murine) Monkey
Chromatin Immunoprecipitation (ChIP) 2 Antibodies
ELISA 57 Antibodies 5 Antibodies
Enzyme Immunoassay (EIA) 8 Antibodies
Flow Cytometry (FACS) 18 Antibodies
Gel Shift (GS) 1 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 27 Antibodies
Immunofluorescence (IF) 54 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies
Immunohistochemistry (IHC) 114 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 37 Antibodies
Immunoprecipitation (IP) 50 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Intracellular Staining (ICS) 13 Antibodies
Western Blotting (WB) 201 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antibodies
Reactivity Human, Monkey, Mouse (Murine)
(544), (265), (208), (30), (24), (24), (12), (11), (10), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(466), (108), (34), (4), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT3 antibody is un-conjugated
(24), (22), (18), (13), (12), (11), (8), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(502), (238), (216), (79), (74), (70), (52), (32), (23), (13), (12), (11), (9), (7), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-STAT3 Antibody

Target Details STAT3 Application Details Handling References for anti-STAT3 Antibody (ABIN1109152) Images
Specificity Recognizes STAT3
Cross-Reactivity (Details) Species reactivity (tested):Human, Monkey, Mouse.
Purification Ascites
Clone 3B5
Isotype IgG1

Target Details STAT3

Product Details anti-STAT3 Antibody Application Details Handling References for anti-STAT3 Antibody (ABIN1109152) Images back to top
Antigen
Alternative Name STAT3 (STAT3 Antibody Abstract)
Background The Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3α (86 kDa) and Stat3β (79 kDa) depend on cell type, ligand exposure or cell maturation stage. It is notable that Stat3β lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.Tissue specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
Molecular Weight 88 kDa
Gene ID 6774
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-STAT3 Antibody Target Details STAT3 Handling References for anti-STAT3 Antibody (ABIN1109152) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details References for anti-STAT3 Antibody (ABIN1109152) Images back to top
Format Liquid

References for anti-STAT3 Antibody (ABIN1109152)

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling Images back to top
Background publications

Schulze, Albers, Baranowsky, Keller, Spiro, Streichert, Zustin, Amling, Schinke: "Osteolytic prostate cancer cells induce the expression of specific cytokines in bone-forming osteoblasts through a Stat3/5-dependent mechanism." in: Bone, Vol. 46, Issue 2, pp. 524-33, 2010

Lin, Buettner, Yuan, Yip, Horne, Jove, Vaidehi: "Molecular dynamics simulations of the conformational changes in signal transducers and activators of transcription, Stat1 and Stat3." in: Journal of molecular graphics & modelling, Vol. 28, Issue 4, pp. 347-56, 2009

Images

Product Details anti-STAT3 Antibody Target Details STAT3 Application Details Handling References for anti-STAT3 Antibody (ABIN1109152) back to top
Supplier Images
Immunofluorescence (IF) image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (ABIN1109152) anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) antibody
Immunohistochemistry (IHC) image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (ABIN1109152) anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) antibody (Image 2)
Western Blotting (WB) image for anti-STAT3 antibody (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor)) (ABIN1109152) anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) antibody (Image 3)