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Human STAT3 ELISA Kit for Sandwich ELISA - ABIN625245
Tukaj, Grüner, Tukaj, Zillikens, Kasperkiewicz: Calcitriol exerts anti-inflammatory effects in keratinocytes treated with autoantibodies from a patient with bullous pemphigoid. in Journal of the European Academy of Dermatology and Venereology : JEADV 2015
fad104 (show FNDC3B ELISA Kits) suppressed anchorage-independent growth of melanoma cells, and the N-terminal region of FAD104 (show FNDC3B ELISA Kits) is essential for inhibiting malignant transformation and STAT3 activity
The data demonstrated that boldine may be beneficial in colitis through selective immunomodulatory effects, which may be mediated, at least in part, by inhibition of p65-NF-kappaB (show NFkBP65 ELISA Kits) and STAT3 signaling pathways
Study showed that suppression of STAT3, STAT5 (show STAT5A ELISA Kits), and STAT6 (show STAT6 ELISA Kits) and overexpression of the proapoptotic factor STAT1 (show STAT1 ELISA Kits), which provides p53 (show TP53 ELISA Kits)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (show ERBB2 ELISA Kits) tyrosine kinase receptor (show KDR ELISA Kits) overexpression promotes neuronal survival through activation of STAT (show STAT1 ELISA Kits)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (show STAT1 ELISA Kits)
inflammatory cytokine insults stimulate epithelial-to-mesenchymal transition (EMT (show ITK ELISA Kits)) as well as the endocrine program in human pancreatic ductal cells via STAT3-dependent NGN3 (show NEUROG3 ELISA Kits) activation.
Study provides evidence for new immunoregulatory mechanisms of STAT3 during intestinal inflammation.
IL-6 (show IL6 ELISA Kits)/P-STAT3 activation influences p63 (show CKAP4 ELISA Kits) isoform expression in healing wounds, which may contribute to wound-induced hair follicle neogenesis.
IL6 (show IL6 ELISA Kits)/STAT3 signalling dysregulation, caused by IL6 (show IL6 ELISA Kits) deficiency, resulted in skewing of the immune modulatory properties of mesenchymal stem cells to favour a pro-inflammatory profile.
These results highlight central nervous system neuronal dependence on STAT3 transcriptional activity.
Our results suggest a protective function of HO-1 induction in psoriasis. The protective effect of HO-1 may be attributed to its effect on the Stat3 signaling pathway via increased SHP-1 expression.
STAT3/Arid1b (show ARID1B ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway is driving neurofibroma initiation.
MCT1 (show CMA1 ELISA Kits) expression associates with the SCC (show CYP11A1 ELISA Kits) type and metastatic behavior of AC, whereas MCT4 expression concomitantly increases from in situ SCC (show CYP11A1 ELISA Kits) to invasive SCC (show CYP11A1 ELISA Kits) and is significantly associated with the AC type. Consistently, FOXM1 (show FOXM1 ELISA Kits) expression is statistically associated with MCT1 (show CMA1 ELISA Kits) positivity in SCC (show CYP11A1 ELISA Kits), whereas the expression of FOXO3a (show FOXO3 ELISA Kits), a FOXM1 (show FOXM1 ELISA Kits) functional antagonist, is linked to MCT1 (show CMA1 ELISA Kits) negativity
MiR (show MLXIP ELISA Kits)-129-5p may directly inhibit STAT3 expression.
Together, these results suggest that the IL-11 (show IL11 ELISA Kits)/STAT3 signaling pathway plays a critical role in human chronic atrophic gastritis , and may provide new targets to prevent and treat gastric cancer
Metformin targets STAT3/NFkappaB signaling to inhibit proliferation/invasiveness of cholangiocarcinoma cells.
Valosin-containing protein (VCP (show vcp ELISA Kits)) promotes the growth, invasion, and metastasis of colorectal cancer through activation of STAT3 signaling.
We determined that IL-17A-induced VEGF upregulation and neovascularization through a Stat3-mediated signaling pathway and hypothesized that blocking the Stat3 activation by using JSI-124, an inhibitor of phosphorylated Stat3, could significantly reduce the VEGF expression and can thus prevent angiogenesis
HCV NS4B contributed to hepatocellular carcinoma by activating the endoplasmic reticulum stress-mediated cancer-related STAT3 pathway.
The protein expression of active caspase-3 (show CASP3 ELISA Kits) increased with STAT3 siRNA treatment, and was significantly higher than that of the control group (P < 0.05). STAT3 gene-silencing significantly improves the apoptotic effect against Bel (show LHX2 ELISA Kits)-7402 cells.
STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.
Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate
results show for the first time that interleukin-6 (show IL6 ELISA Kits) (IL), in the presence of its soluble receptor (show IFNAR1 ELISA Kits) (sIL (show STIL ELISA Kits)-6R), induces activation of JAK1 (show JAK1 ELISA Kits), JAK2 (show JAK2 ELISA Kits), and STAT1 (show STAT1 ELISA Kits)/STAT3 proteins in bovine articular chondrocytes
peroxynitrite causes increased expression of VEGF (show VEGFA ELISA Kits) in vascular endothelial cells by a process that requires the activation of STAT3
Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (show NOX1 ELISA Kits)-mediated activation of STAT3.
maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (show CCND2 ELISA Kits) and PSEN1 (show PSEN1 ELISA Kits) genes via a STAT3-dependent pathway
Studied effect of recombinant porcine leukemia inhibitory factor (show LIF ELISA Kits) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 ELISA Kits)-supplemented media.
Data suggest that IL-6 (interleukin 6 (show IL6 ELISA Kits)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (show IL6 ELISA Kits)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).
the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.
Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.
STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways
Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.
This is the first report of the genetic polymorphisms of the JAK1 (show JAK1 ELISA Kits) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.
Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.
Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (show MMP2 ELISA Kits) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.
PTPN9 (show PTPN9 ELISA Kits) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (show GATA1 ELISA Kits) and ZBP-89 (show ZNF148 ELISA Kits).
Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.
Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.
This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.
The results of this study suggested that the stat3/socs3 (show SOCS3 ELISA Kits) pathway is a key response in all tissue regeneration in zebrafish.
stat3, a known oncogene (show RAB1A ELISA Kits) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.
Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (show PRCP ELISA Kits) in neighboring cells during zebrafish gastrulation.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
signal transducer and activator of transcription 3 (acute-phase response factor)
, signal transducer and activator of transcription 3
, signal transduction and activation of transcription 3
, Signal transducer and activator of transcription 3
, signal transducer and activator of transcription 3-like
, acute phase response factor
, acute-phase response factor
, DNA-binding protein APRF
, Protein Stat3
, signal transducer and activator of transcription 3.1
, stat 3