Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Human STAT3 ELISA Kit for Sandwich ELISA - ABIN625245
Tukaj, Grüner, Tukaj, Zillikens, Kasperkiewicz: Calcitriol exerts anti-inflammatory effects in keratinocytes treated with autoantibodies from a patient with bullous pemphigoid. in Journal of the European Academy of Dermatology and Venereology : JEADV 2015
findings demonstrate that advanced gastric tumorigenesis requires oncogenic KRAS or BRAF (show BRAF ELISA Kits) in concert with aberrant STAT3 activation in epithelial precursor cells of the glandular stomach
phosphorylated Hsp27 (show HSPB1 ELISA Kits) stimulates autophagy and lipid droplet clearance and interacts with STAT3.
Treatment with Tetrandrine (TET) resulted in downregulation of phosphorylated NFkappaB p65 (show NFkBP65 ELISA Kits) and reduction of the production of TNFalpha (show TNF ELISA Kits) and IL1beta (show IL1B ELISA Kits). In addition, the phosphorylation of ERK (show EPHB2 ELISA Kits) and STAT3 was decreased by TET in activated macrophages.
fad104 (show FNDC3B ELISA Kits) suppressed anchorage-independent growth of melanoma cells, and the N-terminal region of FAD104 (show FNDC3B ELISA Kits) is essential for inhibiting malignant transformation and STAT3 activity
The data demonstrated that boldine may be beneficial in colitis through selective immunomodulatory effects, which may be mediated, at least in part, by inhibition of p65-NF-kappaB (show NFkBP65 ELISA Kits) and STAT3 signaling pathways
Study showed that suppression of STAT3, STAT5 (show STAT5A ELISA Kits), and STAT6 (show STAT6 ELISA Kits) and overexpression of the proapoptotic factor STAT1 (show STAT1 ELISA Kits), which provides p53 (show TP53 ELISA Kits)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (show ERBB2 ELISA Kits) tyrosine kinase receptor (show KDR ELISA Kits) overexpression promotes neuronal survival through activation of STAT (show STAT1 ELISA Kits)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (show STAT1 ELISA Kits)
inflammatory cytokine insults stimulate epithelial-to-mesenchymal transition (EMT (show ITK ELISA Kits)) as well as the endocrine program in human pancreatic ductal cells via STAT3-dependent NGN3 (show NEUROG3 ELISA Kits) activation.
Study provides evidence for new immunoregulatory mechanisms of STAT3 during intestinal inflammation.
IL-6 (show IL6 ELISA Kits)/P-STAT3 activation influences p63 (show CKAP4 ELISA Kits) isoform expression in healing wounds, which may contribute to wound-induced hair follicle neogenesis.
IL6 (show IL6 ELISA Kits)/STAT3 signalling dysregulation, caused by IL6 (show IL6 ELISA Kits) deficiency, resulted in skewing of the immune modulatory properties of mesenchymal stem cells to favour a pro-inflammatory profile.
Huaier aqueous extract inhibited JAK2 (show JAK2 ELISA Kits)/STAT3 and MAPK (show MAPK1 ELISA Kits) signaling pathways.
MiR-451 may function as a potential suppressor of tumor angiogenesis in HCC by targeting IL-6R-STAT3-VEGF signaling, suggesting.
Data show that the activation of STAT3 protein upregulated human cervical cancer oncogene (show RAB1A ELISA Kits) (HCCR) expression in gastric cancer cells.
These results suggested that STAT3 activation represents a potential target in nasal Nasal-type natural killer/T-cell lymphoma(NKTCL). WP1066 may be a promising agent in antitumor therapy against nasal NKTCL.
The findings of the present study suggested that miR (show MLXIP ELISA Kits)-124 functioned as tumor suppressor in retinoblastoma , at least in part, by targeting STAT3, and that it could serve as a potential candidate for retinoblastoma therapeutics.
Imatinib-resistant K562/G01 cells expressed significantly higher levels of STAT3 and RPS27a (show RPS27A ELISA Kits) compared with those of K562 cells.
results suggest that methanethiosulfonate moiety can be considered a useful scaffold in the preparation of new direct STAT3 inhibitors
Data show that Rac1 induced nuclear import of STAT3 by physical binding, and nuclear STAT3 directly activated the transcription of essential oocyte-specific genes, including Jagged1 (show JAG1 ELISA Kits), GDF9 (show GDF9 ELISA Kits) and BMP15 (show BMP15 ELISA Kits).
High STAT3 expression is associated with leukemia.
results suggest that the activation of the IL6/STAT3 pathway in tumor cells may provide a survival advantage during anti-VEGF treatment, suggesting its utility as a source of response biomarkers and as a therapeutic target to heighten efficacious results
STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.
Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate
results show for the first time that interleukin-6 (show IL6 ELISA Kits) (IL), in the presence of its soluble receptor (show IFNAR1 ELISA Kits) (sIL (show STIL ELISA Kits)-6R), induces activation of JAK1 (show JAK1 ELISA Kits), JAK2 (show JAK2 ELISA Kits), and STAT1 (show STAT1 ELISA Kits)/STAT3 proteins in bovine articular chondrocytes
peroxynitrite causes increased expression of VEGF (show VEGFA ELISA Kits) in vascular endothelial cells by a process that requires the activation of STAT3
Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (show NOX1 ELISA Kits)-mediated activation of STAT3.
maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (show CCND2 ELISA Kits) and PSEN1 (show PSEN1 ELISA Kits) genes via a STAT3-dependent pathway
Studied effect of recombinant porcine leukemia inhibitory factor (show LIF ELISA Kits) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 ELISA Kits)-supplemented media.
Data suggest that IL-6 (interleukin 6 (show IL6 ELISA Kits)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (show IL6 ELISA Kits)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).
the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.
Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.
STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways
Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.
This is the first report of the genetic polymorphisms of the JAK1 (show JAK1 ELISA Kits) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.
Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.
Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (show MMP2 ELISA Kits) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.
PTPN9 (show PTPN9 ELISA Kits) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (show GATA1 ELISA Kits) and ZBP-89 (show ZNF148 ELISA Kits).
Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.
Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.
This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.
The results of this study suggested that the stat3/socs3 (show SOCS3 ELISA Kits) pathway is a key response in all tissue regeneration in zebrafish.
stat3, a known oncogene (show RAB1A ELISA Kits) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.
Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (show PRCP ELISA Kits) in neighboring cells during zebrafish gastrulation.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
signal transducer and activator of transcription 3 (acute-phase response factor)
, signal transducer and activator of transcription 3
, signal transduction and activation of transcription 3
, Signal transducer and activator of transcription 3
, signal transducer and activator of transcription 3-like
, acute phase response factor
, acute-phase response factor
, DNA-binding protein APRF
, Protein Stat3
, signal transducer and activator of transcription 3.1
, stat 3