anti-Human STAT5A antibody for Western Blotting

Recommended STAT5A Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 5A (STAT5A) Antibodies
  • STAT5A
  • STAT5
  • MGF
  • AA959963
  • Stat5
  • STAT5A/MGF
  • STATA5
  • signal transducer and activator of transcription 5A
  • signal transducer and activator of transcription 5A-like
  • signal transducer and activator of transcription 5B
  • STAT5A
  • Stat5a
  • LOC100348518
  • STAT5B
Epitope
C-Term
102
55
47
22
19
16
9
8
6
6
5
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
502
230
198
34
23
18
17
16
7
3
3
1
1
1
1
Host
Rabbit
358
150
14
Clonality
Polyclonal
Conjugate
This STAT5A antibody is un-conjugated
13
13
11
9
9
9
5
5
5
5
5
5
5
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
397
234
163
96
95
89
47
44
26
17
11
9
7
7
6
4
3
2
2
1
1
1
1
1
1
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Catalog No. ABIN2780480
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN1533730 ELISA WB Rabbit IgG AA 386-435 Log in to see Polyclonal 1
3.2182703 ABIN2801340 IHC WB Rabbit C-Term Log in to see Polyclonal
3.2182703 ABIN2705263 IP IHC WB Rabbit C-Term Log in to see Polyclonal
3.2182703 ABIN2705264 IHC WB Rabbit C-Term Log in to see Polyclonal
3.2182703 ABIN2705265 IHC WB Rabbit C-Term, pTyr694, pTyr699 Log in to see Polyclonal
3.2182703 ABIN2707111 IHC WB Rabbit Center Log in to see Polyclonal
3.2182703 ABIN223189 IP IHC WB Rabbit IgG Log in to see Polyclonal
3.2182703 ABIN967811 IF IP IHC WB Mouse IgG2b AA 451-649 Log in to see 89-Stat5 5
3.2182703 ABIN967810 IF IP IHC WB Mouse IgG2b AA 451-649 Log in to see 89-Stat5 5
3.2182703 ABIN389668 IF IHC (p) WB Rabbit Ig pTyr694 Log in to see Polyclonal 1
3.2182703 ABIN964687 IHC ELISA WB Mouse IgG1 kappa pTyr694, Internal Region Log in to see 5F6-F1
3.2182703 ABIN1098129 ICC FACS IHC ELISA WB Mouse IgG1 AA 583-794 Log in to see 6D4 2
3.2182703 ABIN1533012 IHC ELISA WB Rabbit IgG AA 745-794 Log in to see Polyclonal
3.2182703 ABIN1533013 IHC ELISA WB Rabbit IgG AA 666-715 Log in to see Polyclonal
3.2182703 ABIN1531977 ELISA IHC IP WB Rabbit IgG AA 745-794, pSer780 Log in to see Polyclonal
3.2182703 ABIN1531978 IHC ELISA WB Rabbit IgG AA 666-715, pTyr694 Log in to see Polyclonal
3.2182703 ABIN3187087 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
3.2182703 ABIN3187088 ELISA IHC WB Rabbit IgG Tyr1248 Log in to see Polyclonal
3.2182703 ABIN3182499 ELISA IHC WB Rabbit IgG pSer726, pSer731 Log in to see Polyclonal
3.2182703 ABIN3187091 ELISA IHC WB Rabbit IgG Log in to see Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 5A (STAT5A) Antibodies
Epitope C-Term
(102), (55), (47), (22), (19), (16), (9), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Goat, Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
(502), (230), (198), (34), (23), (18), (17), (16), (7), (3), (3), (1), (1), (1), (1)
Host Rabbit
(358), (150), (14)
Clonality
Polyclonal
Conjugate This STAT5A antibody is un-conjugated
(13), (13), (11), (9), (9), (9), (5), (5), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(397), (234), (163), (96), (95), (89), (47), (44), (26), (17), (11), (9), (7), (7), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-STAT5A Antibody

Target Details STAT5A Application Details Handling References for anti-STAT5A antibody (ABIN2780480) Images
Blocking Peptide Blocking peptide for this product available: ABIN984531
Sequence DQAPSPAVCP QAPYNMYPQN PDHVLDQDGE FDLDETMDVA RHVEELLRRP
Predicted Reactivity Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 86%, Rat: 92%, Sheep: 93%
Characteristics This is a rabbit polyclonal antibody against STAT5A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human STAT5A

Target Details STAT5A

Product Details anti-STAT5A Antibody Application Details Handling References for anti-STAT5A antibody (ABIN2780480) Images back to top
Antigen
Alternative Name STAT5A (STAT5A Antibody Abstract)
Background STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGF, STAT5
Protein Interaction Partner: TCF12, NLK, LEF1, NARF, CBL, UBC, ESR1, HELZ, UGT2B4, STAT5A, POM121C, WASH2P, AQP11, ZNF596, MRPS6, TXNDC11, RBMX, INSR, GLUD1, FN1, EPAS1, CYP2C9, CSNK2B, JAK2, BTK, EPOR, CRKL, SOCS7, NFKB1, ERBB4, EP300, MYB, SQSTM1, GNB2, SMARCA4, PGR, FGFR2, JAK3, C
Protein Size: 794
Molecular Weight 91 kDa
Gene ID 6776
NCBI Accession NM_003152, NP_003143
UniProt P42229
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation

Application Details

Product Details anti-STAT5A Antibody Target Details STAT5A Handling References for anti-STAT5A antibody (ABIN2780480) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 794 AA

Restrictions For Research Use only

Handling

Product Details anti-STAT5A Antibody Target Details STAT5A Application Details References for anti-STAT5A antibody (ABIN2780480) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-STAT5A antibody (ABIN2780480)

Product Details anti-STAT5A Antibody Target Details STAT5A Application Details Handling Images back to top
Product cited in:

Murayama, Ohmori, Fujimura, Minami, Yasuzawa-Tanaka, Kuroda, Oie, Daitoku, Okuwaki, Nagata, Fukamizu, Kimura, Shimizu, Yanagisawa: "Epigenetic control of rDNA loci in response to intracellular energy status." in: Cell, Vol. 133, Issue 4, pp. 627-39, 2008

Background publications

Subtil-Rodríguez, Millán-Ariño, Quiles, Ballaré, Beato, Jordan: "Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking." in: Molecular and cellular biology, Vol. 28, Issue 11, pp. 3830-49, 2008

Images

Product Details anti-STAT5A Antibody Target Details STAT5A Application Details Handling References for anti-STAT5A antibody (ABIN2780480) back to top
Supplier Images
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody (ABIN2780480) anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody