anti-Mouse (Murine) STAT5A antibody for Flow Cytometry

Recommended STAT5A Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 5A (STAT5A) Antibodies
  • STAT5A
  • STAT5
  • MGF
  • AA959963
  • Stat5
  • STAT5A/MGF
  • STATA5
  • signal transducer and activator of transcription 5A
  • signal transducer and activator of transcription 5A-like
  • signal transducer and activator of transcription 5B
  • STAT5A
  • Stat5a
  • LOC100348518
  • STAT5B
Reactivity
Human, Mouse (Murine)
493
230
199
35
24
19
17
17
7
4
4
1
1
1
1
1
1
Host
Mouse
359
140
14
Clonality
Monoclonal
Conjugate
This STAT5A antibody is un-conjugated
13
13
11
9
8
8
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
398
234
163
96
89
85
46
43
26
17
11
9
7
7
6
4
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN2666295
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4914357 FACS PE Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN2367489 FACS ELISA WB Rabbit IgG pTyr694 Log in to see Polyclonal
1 ABIN3060440 FACS IP IHC WB Rabbit Log in to see Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 5A (STAT5A) Antibodies
Reactivity Human, Mouse (Murine)
(493), (230), (199), (35), (24), (19), (17), (17), (7), (4), (4), (1), (1), (1), (1), (1), (1)
Host Mouse
(359), (140), (14)
Clonality (Clone)
Monoclonal   ( )
Conjugate This STAT5A antibody is un-conjugated
(13), (13), (11), (9), (8), (8), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(398), (234), (163), (96), (89), (85), (46), (43), (26), (17), (11), (9), (7), (7), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-STAT5A Antibody

Target Details STAT5A Application Details Handling References for anti-STAT5A antibody (ABIN2666295) Images
Purification Affinity purified.
Clone 9C8B50
Isotype IgG2a kappa

Target Details STAT5A

Product Details anti-STAT5A Antibody Application Details Handling References for anti-STAT5A antibody (ABIN2666295) Images back to top
Antigen
Alternative Name STAT5 (STAT5A Antibody Abstract)
Background STAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine signaling. STAT5 consists of two closely related family members, STAT5A and STAT5B, which exhibit 96 % sequence homology and are functionally redundant. Upon activation, STAT5 is phosphorylated by receptor tyrosine kinases and, in turn, forms homodimers or hererodimers with other family members through its SH2 domains. The dimerized STAT5 translocates to the nucleus and binds to the STAT5 response element (TTCXXXGAA). STAT5 plays crucial regulatory roles in cell proliferation, anti-apoptosis, early B cell differentiation, and T cell development.
Research Area Cancer, Transcription Factors, Signaling, Receptors, Inflammation
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation

Application Details

Product Details anti-STAT5A Antibody Target Details STAT5A Handling References for anti-STAT5A antibody (ABIN2666295) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-STAT5A Antibody Target Details STAT5A Application Details References for anti-STAT5A antibody (ABIN2666295) Images back to top
Concentration 0.5 mg/mL
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Upon receipt, store undiluted between 2°C and 8°C.

References for anti-STAT5A antibody (ABIN2666295)

Product Details anti-STAT5A Antibody Target Details STAT5A Application Details Handling Images back to top
Background publications

Bell, Kitajima, Larson, Stoklasek, Dang, Sakamoto, Wagner, Kaplan, Reizis, Hennighausen, Ziegler: "The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses." in: Nature immunology, Vol. 14, Issue 4, pp. 364-71, 2013

Heltemes-Harris, Farrar: "The role of STAT5 in lymphocyte development and transformation." in: Current opinion in immunology, Vol. 24, Issue 2, pp. 146-52, 2012

Cholez, Debuysscher, Bourgeais, Boudot, Leprince, Tron, Brassart, Regnier, Bissac, Pecnard, Gouilleux, Lassoued, Gouilleux-Gruart: "Evidence for a protective role of the STAT5 transcription factor against oxidative stress in human leukemic pre-B cells." in: Leukemia, Vol. 26, Issue 11, pp. 2390-7, 2012

Heltemes-Harris, Willette, Vang, Farrar: "The role of STAT5 in the development, function, and transformation of B and T lymphocytes." in: Annals of the New York Academy of Sciences, Vol. 1217, pp. 18-31, 2011

Xu, Chen, Chen, Xiao, Hsu, Michael, Bao: "STAT5 mediates antiapoptotic effects of methylprednisolone on oligodendrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 7, pp. 2022-6, 2009

Images

Product Details anti-STAT5A Antibody Target Details STAT5A Application Details Handling References for anti-STAT5A antibody (ABIN2666295) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody (ABIN2666295) anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody (ABIN2666295) anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody (Image 2)