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Browse our anti-STAT5B (STAT5B) Antibodies

Full name:
anti-Signal Transducer and Activator of Transcription 5B Antibodies (STAT5B)
On www.antibodies-online.com are 195 Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies from 27 different suppliers available. Additionally we are shipping STAT5B Kits (29) and STAT5B Proteins (9) and many more products for this protein. A total of 249 STAT5B products are currently listed.
Synonyms:
STAT5, STAT5A, stat5b
list all antibodies Gene Name GeneID UniProt
STAT5B 6777 P51692
STAT5B 20851 P42232
STAT5B 25126 P52632

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Most Popular Reactivities for anti-STAT5B (STAT5B) Antibodies

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anti-Human STAT5B Antibodies:

anti-Mouse (Murine) STAT5B Antibodies:

anti-Rat (Rattus) STAT5B Antibodies:

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Top referenced anti-STAT5B Antibodies

  1. Human Polyclonal STAT5B Primary Antibody for EIA, IHC (p) - ABIN357079 : Xi, Zhang, Gooding, Smithgall, Grandis: Constitutive activation of Stat5b contributes to carcinogenesis in vivo. in Cancer research 2003 (PubMed)
    Show all 5 references for ABIN357079

  2. Chicken Polyclonal STAT5B Primary Antibody for IHC, WB - ABIN2780885 : Mohankumar, Perry, Kannan, Kohno, Gluckman, Emerald, Lobie: Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell. in Endocrinology 2008 (PubMed)

  3. Human Polyclonal STAT5B Primary Antibody for IHC, ELISA - ABIN1532264 : Pullen, Barnstein, Falanga, Wang, Suzuki, Lama Tamang, Khurana, Harry, Rivera, Draber, Bunting, Mizuno, Wilson, Ryan: A novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (Stat5) tyrosine phosphorylation and the selective influence of Stat5B over mast cell cytokine production. in The Journal of biological chemistry 2011 (PubMed)

  4. Chicken Polyclonal STAT5B Primary Antibody for IHC, WB - ABIN2779971 : Laloraya, Davoodi-Semiromi, Kumar, McDuffie, She: Impaired Crkl expression contributes to the defective DNA binding of Stat5b in nonobese diabetic mice. in Diabetes 2006 (PubMed)

More Antibodies against STAT5B Interaction Partners

Zebrafish Signal Transducer and Activator of Transcription 5B (STAT5B) interaction partners

  1. This study indicates that CISH (show CISH Antibodies) functions as a conserved in vivo target and regulator of STAT5 in the control of embryonic hematopoiesis.

  2. study demonstrates that STAT5 in basophils is activated through both the IL-3 (show Il3 Antibodies) and the FcepsilonRI (show FCER1G Antibodies) signaling pathway

  3. Studies demonstrate a conserved role for SOCS1 (show SOCS1 Antibodies) in T cell development and suggest a novel T cell-independent function in embryonic myelopoiesis mediated, at least in part, via its effects on receptors using the Jak2 (show JAK2 Antibodies)-Stat5 pathway.

  4. The stat5.1 gene lies next to the stat3 (show STAT3 Antibodies) gene.

Human Signal Transducer and Activator of Transcription 5B (STAT5B) interaction partners

  1. STAT5 (show STAT5A Antibodies) activation by EGF (show EGF Antibodies) constitutes an important cascade for the regulation of cell proliferation and invasion in trophoblast cells.

  2. MSM decreased the ability of STAT5b to bind the promoter of the HER2 (show ERBB2 Antibodies) gene.

  3. Results confirm that STAT5B is mutated in T-PLL and underscore the potential therapeutical relevance of epigenetic regulator.

  4. ABL (show ABL1 Antibodies)-N administration induced apoptosis of PC3 (show PCSK1 Antibodies) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (show BAX Antibodies)/Bcl-2 (show BCL2 Antibodies) ratio. Expression of KLF5 (show KLF5 Antibodies), Stat5b and ICAM-1 (show ICAM1 Antibodies) was significantly downregulated in PC3 (show PCSK1 Antibodies) cells.

  5. The two STAT5 (show STAT5A Antibodies) isoforms, STAT5a (show STAT5A Antibodies) and STAT5b.

  6. support the concept that Jak2 (show JAK2 Antibodies)-Stat5a (show STAT5A Antibodies)/b signaling promotes metastatic progression of prostate cancer by inducing epithelial-to-mesenchymal transition and stem cell properties in prostate cancer cells

  7. Interference of STAT (show STAT1 Antibodies) 5b expression by siRNA targeting enhanced the chemo-sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway-mediated cell apoptosis.

  8. Both Stat5a (show STAT5A Antibodies)/b genetic knockdown and antiandrogen treatment induced proteasomal degradation of AR in prostate cancer cells.

  9. Our study also assessed the regulation of signaling molecules implicated in the growth, progression, differentiation, and migration of cancer cells, such as Jak2 (show JAK2 Antibodies), STAT5b, insulin (show INS Antibodies)-like growth factor-1Rbeta, and their phosphorylation status

  10. STAT3 (show STAT3 Antibodies) and STAT5B mutations are associated with increased phosphorylated protein and a growth advantage to transduced cell lines or normal NK cells

Pig (Porcine) Signal Transducer and Activator of Transcription 5B (STAT5B) interaction partners

  1. A study of the polymorphisms of STAT5b is presented, and the use of radiation hybrid mapping to localize the gene to chromosome 12 is presented.

Cow (Bovine) Signal Transducer and Activator of Transcription 5B (STAT5B) interaction partners

  1. SNPs in JAK2 (show JAK2 Antibodies) and STAT5B are associated with mastitis susceptibility in Chinese Holstein cattle

  2. This study suggests that growth hormone (show GH1 Antibodies) inhibits the differentiation of bovine preadipocytes to adipocytes through STAT5b-dependent inhibition of C/EBPalpha (show CEBPA Antibodies) and PPARgamma (show PPARG Antibodies) expression.

  3. These results suggested that the SNPs in CD4 (show CD4 Antibodies) and STAT5b may be potential genetic markers for SCS (show TWIST1 Antibodies) and milk/protein (show CSN2 Antibodies) yields selecting and warrant further functional research.

Mouse (Murine) Signal Transducer and Activator of Transcription 5B (STAT5B) interaction partners

  1. STAT5B and MOF (show KAT8 Antibodies) work as negative regulators in adipogenesis.

  2. Strong selective advantage for leukemic transformation in the background of Stat5 (show STAT5A Antibodies) deficient hematopoiesis was permissive for faster initiation of Myc (show MYC Antibodies)-induced transformation to B (show TDO2 Antibodies)-ALL.

  3. liver STAT5b activation/masculinization occurred at puberty and suppression/feminization occurred during aging and in mutant mice with defects in growth hormone (show GH1 Antibodies) signaling.

  4. Loss of STAT5b had no effect on either sex.

  5. These data provide the first definitive evidence for a contribution of STAT5a (show STAT5A Antibodies)/b to the sex bias in pulmonary hypertension in the hypoxic mouse and implicate reduced STAT5 (show STAT5A Antibodies) in the pathogenesis of the human disease.

  6. Data show that three hypotheses of dimer formation between STAT5 (show STAT5A Antibodies) transcription factors STAT5A (show STAT5A Antibodies) and STAT5B were used to explain the analytical results by a static mathematical model.

  7. Increased expression of STAT5b + PDGFB (show PDGFB Antibodies) led to increased expression of downstream STAT5b targets.

  8. Expression of miR (show MLXIP Antibodies)-21 is under prolactin (show PRL Antibodies) control through the transcription factors STAT5A (show STAT5A Antibodies)/B.

  9. non-obese-diabetic genetic background is critical to the Stat5b-mediated lymphomagenesis through regulation of Stat5 (show STAT5A Antibodies) hyperactivation

  10. STAT5b but not STAT5a (show STAT5A Antibodies) is the primary mediator of the action of prolactin (show PRL Antibodies) in the hypothalamus.

STAT5B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5B

  • signal transducer and activator of transcription 5B (STAT5B) antibody
  • Signal transducer and activator of transcription 5B (sta5b) antibody
  • signal transducer and activator of transcription 5B (stat5b) antibody
  • signal transducer and activator of transcription 5.1 (stat5.1) antibody
  • signal transducer and activator of transcription 5B (Stat5b) antibody
  • signal transducer and activator of transcription 5B (LOC789476) antibody
  • signal transducer and activator of transcription 5B-like (LOC100348267) antibody
  • STAT5 antibody
  • STAT5A antibody
  • stat5b antibody

Protein level used designations for STAT5B

signal transducer and activator of transcription 5A , Signal transducer and activator of transcription 5B , signal transducer and activator of transcription 5B , transcription factor STAT5B , mammary gland factor STAT5B , Signal transducer and activator of transcription 5a

GENE ID SPECIES
454679 Pan troglodytes
100380532 Salmo salar
100566752 Anolis carolinensis
369197 Danio rerio
395556 Gallus gallus
414637 Xenopus laevis
6777 Homo sapiens
490969 Canis lupus familiaris
397340 Sus scrofa
282376 Bos taurus
20851 Mus musculus
25126 Rattus norvegicus
100716532 Cavia porcellus
789476 Bos taurus
101122961 Ovis aries
100348267 Oryctolagus cuniculus
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