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anti-Cow (Bovine) STAT5B antibody for Western Blotting

Recommended STAT5B Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
  • STAT5
  • stat5
  • Stat5
  • STAT5A
  • stat5b
Epitope
C-Term
35
21
12
8
6
5
5
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
182
81
69
7
7
7
6
4
3
2
Host
Rabbit
134
60
Clonality
Polyclonal
Conjugate
This STAT5B antibody is un-conjugated
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
149
70
61
34
29
22
14
7
7
3
2
1
1
1
1
Supplier
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Catalog No. ABIN2780885
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13435054 ABIN2780884 IHC WB Rabbit N-Term Log in to see Polyclonal 1
0.13435054 ABIN2779971 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
0.13435054 ABIN927757 WB Rabbit C-Term Log in to see Polyclonal
0.13435054 ABIN927756 WB Rabbit N-Term Log in to see Polyclonal
0.13435054 ABIN927442 WB Rabbit N-Term Log in to see Polyclonal
0.13435054 ABIN925835 WB Rabbit Middle Region Log in to see Polyclonal
0.0011739617 ABIN2777898 IHC WB Rabbit N-Term Log in to see Polyclonal 1

Top referenced anti-STAT5B antibody for Western Blotting

Similar anti-STAT5B Antibodies

Application / Reactivity Chicken Cow (Bovine) Human Mouse (Murine) Pig (Porcine) Rat (Rattus) Zebrafish (Danio rerio)
Western Blotting (WB) 8 Antibodies 8 Antibodies 139 Antibodies 60 Antibodies 8 Antibodies 48 Antibodies 3 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 6 Antibodies 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 35 Antibodies 11 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 4 Antibodies 4 Antibodies 61 Antibodies 33 Antibodies 4 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
Epitope C-Term
(35), (21), (12), (8), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
(182), (81), (69), (7), (7), (7), (6), (4), (3), (2)
Host Rabbit
(134), (60)
Clonality
Polyclonal
Conjugate This STAT5B antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(149), (70), (61), (34), (29), (22), (14), (7), (7), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT5B Antibody

Target Details STAT5B Application Details Handling References for anti-STAT5B Antibody (ABIN2780885) Images
Blocking Peptide Blocking peptide for this product available: ABIN984536
Sequence GSATYMDQAP SPAVCPQAHY NMYPQNPDSV LDTDGDFDLE DTMDVARRVE
Predicted Reactivity Human : 100 %, Rabbit : 100 %, Horse : 90 %, Pig : 80 %, Chicken : 70 %, Dog : 70 %
Characteristics This is a rabbit polyclonal antibody against STAT5B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human STAT5B

Target Details STAT5B

Product Details anti-STAT5B Antibody Application Details Handling References for anti-STAT5B Antibody (ABIN2780885) Images back to top
Antigen
Alternative Name STAT5B (STAT5B Antibody Abstract)
Background STAT5B is a member of the STAT family of transcription factors. In response to cytokines andgrowth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Molecular Weight 90 kDa
Gene ID 6777
NCBI Accession NP_036580, NM_012448
UniProt P51692
Pathways JAK-STAT Signaling, RTK Signaling

Application Details

Product Details anti-STAT5B Antibody Target Details STAT5B Handling References for anti-STAT5B Antibody (ABIN2780885) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 787 AA

Restrictions For Research Use only

Handling

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details References for anti-STAT5B Antibody (ABIN2780885) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-STAT5B Antibody (ABIN2780885)

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling Images back to top
Background publications

Mohankumar, Perry, Kannan, Kohno, Gluckman, Emerald, Lobie: "Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell." in: Endocrinology, Vol. 149, Issue 5, pp. 2219-29, 2008

Images

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling References for anti-STAT5B Antibody (ABIN2780885) back to top
Supplier Images
Western Blotting (WB) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (C-Term) (ABIN2780885) anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (C-Term) antibody