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anti-Human STAT5B antibody for Western Blotting

Recommended STAT5B Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
  • STAT5A
  • Stat5
  • stat5
  • stat5b
  • STAT5
  • signal transducer and activator of transcription 5B
  • Signal transducer and activator of transcription 5B
  • signal transducer and activator of transcription 5.1
  • signal transducer and activator of transcription 5B-like
  • STAT5B
  • sta5b
  • stat5b
  • stat5.1
  • Stat5b
  • LOC789476
  • LOC100348267
Epitope
C-Term
32
22
11
10
6
5
5
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
193
96
89
15
13
12
9
6
4
4
3
2
2
2
2
1
Host
Rabbit
137
64
Clonality
Polyclonal
Conjugate
This STAT5B antibody is un-conjugated
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
155
71
62
34
29
26
16
10
7
3
3
2
1
1
1
1
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Catalog No. ABIN2780885
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.0742016 ABIN2780884 IHC WB Rabbit N-Term Log in to see Polyclonal 1
3.0742016 ABIN2779971 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
3.0742016 ABIN1532264 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
3.0742016 ABIN4900487 FACS ICC IP SimWes WB Rabbit IgG AA 777-787 Log in to see Polyclonal 1
3.0742016 ABIN3042740 WB Rabbit IgG AA 675-703, C-Term Log in to see Polyclonal
3.0742016 ABIN388363 IHC (p) WB Rabbit Ig AA 760-787, C-Term Log in to see Polyclonal
3.0742016 ABIN1531246 IHC ELISA WB Rabbit IgG pSer731 Log in to see Polyclonal
3.0742016 ABIN3044204 IHC (p) WB Rabbit IgG AA 767-787, C-Term Log in to see Polyclonal
3.0742016 ABIN781828 EIA IF IHC (p) WB Mouse IgG1 Log in to see 5D6
3.0742016 ABIN781829 EIA IF IHC (p) WB Mouse IgG1 Log in to see 2D1
3.0742016 ABIN3188052 IHC WB Rabbit IgG Log in to see Polyclonal
3.0742016 ABIN498182 IHC (p) WB Rabbit Log in to see Polyclonal
3.0742016 ABIN393592 IF WB Mouse IgG1 kappa AA 678-788 Log in to see 2D1
3.0742016 ABIN393832 IF WB Mouse IgG1 kappa AA 678-788 Log in to see 5D6
3.0742016 ABIN2458020 ELISA WB Rabbit Log in to see Polyclonal
3.0742016 ABIN2461837 ELISA WB Rabbit Log in to see Polyclonal
3.0742016 ABIN2458355 ELISA WB Rabbit Log in to see Polyclonal
3.0742016 ABIN969422 ELISA WB Mouse IgG1 Log in to see 5B3
3.0742016 ABIN393432 IF WB Mouse IgG1 kappa AA 1-391 Log in to see 1A1
3.0742016 ABIN1874969 IF IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-STAT5B antibody for Western Blotting

  • Human Polyclonal STAT5B Primary Antibody for IHC, ELISA - ABIN1532264 (1 Publications): Pullen, Barnstein, Falanga, Wang, Suzuki, Lama Tamang, Khurana, Harry, Rivera, Draber, Bunting, Mizuno, Wilson, Ryan: A novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (Stat5) tyrosine phosphorylation and the selective influence of Stat5B over mast cell cytokine production. in The Journal of biological chemistry 2011 (PubMed)

  • Human Polyclonal STAT5B Primary Antibody for FACS, ICC - ABIN4900487 (1 Publications): Kawashima, Bao, Nomura, Moon, Tonozuka, Minoshima, Hatori, Tsuchiya, Kiyono, Nosaka, Nakajima, Williams, Kitamura: Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors. in The Journal of cell biology 2006 (PubMed)

Similar anti-STAT5B Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Chicken Cow (Bovine) Pig (Porcine) Zebrafish (Danio rerio)
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 2 Antibodies 2 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies
Western Blotting (WB) 10 Antibodies 13 Antibodies 148 Antibodies 71 Antibodies 16 Antibodies 63 Antibodies 3 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 9 Antibodies 13 Antibodies 3 Antibodies 5 Antibodies 3 Antibodies 1 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
Epitope C-Term
(32), (22), (11), (10), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Zebrafish (Danio rerio)
(193), (96), (89), (15), (13), (12), (9), (6), (4), (4), (3), (2), (2), (2), (2), (1)
Host Rabbit
(137), (64)
Clonality
Polyclonal
Conjugate This STAT5B antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(155), (71), (62), (34), (29), (26), (16), (10), (7), (3), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-STAT5B Antibody

Target Details STAT5B Application Details Handling References for anti-STAT5B Antibody (ABIN2780885) Images
Blocking Peptide Blocking peptide for this product available: ABIN984536
Sequence GSATYMDQAP SPAVCPQAHY NMYPQNPDSV LDTDGDFDLE DTMDVARRVE
Predicted Reactivity Human : 100 %, Rabbit : 100 %, Horse : 90 %, Pig : 80 %, Chicken : 70 %, Dog : 70 %
Characteristics This is a rabbit polyclonal antibody against STAT5B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human STAT5B

Target Details STAT5B

Product Details anti-STAT5B Antibody Application Details Handling References for anti-STAT5B Antibody (ABIN2780885) Images back to top
Antigen
Alternative Name STAT5B (STAT5B Antibody Abstract)
Background STAT5B is a member of the STAT family of transcription factors. In response to cytokines andgrowth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Molecular Weight 90 kDa
Gene ID 6777
NCBI Accession NM_012448, NP_036580
UniProt P51692
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process

Application Details

Product Details anti-STAT5B Antibody Target Details STAT5B Handling References for anti-STAT5B Antibody (ABIN2780885) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 787 AA

Restrictions For Research Use only

Handling

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details References for anti-STAT5B Antibody (ABIN2780885) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-STAT5B Antibody (ABIN2780885)

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling Images back to top
Background publications

Mohankumar, Perry, Kannan, Kohno, Gluckman, Emerald, Lobie: "Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell." in: Endocrinology, Vol. 149, Issue 5, pp. 2219-29, 2008

Images

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling References for anti-STAT5B Antibody (ABIN2780885) back to top
Supplier Images
Western Blotting (WB) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (C-Term) (ABIN2780885) anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (C-Term) antibody