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anti-Mouse (Murine) STAT5B antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended STAT5B Antibody (supplied by: Log in to see )

Antigen
Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
  • STAT5A
  • Stat5
  • stat5
  • stat5b
  • STAT5
  • signal transducer and activator of transcription 5B
  • Signal transducer and activator of transcription 5B
  • signal transducer and activator of transcription 5.1
  • signal transducer and activator of transcription 5B-like
  • STAT5B
  • sta5b
  • stat5b
  • stat5.1
  • Stat5b
  • LOC789476
  • LOC100348267
Reactivity
Human, Mouse (Murine), Rat (Rattus)
204
98
92
15
14
13
11
9
7
6
6
4
2
2
2
1
Host
Rabbit
140
71
Clonality
Polyclonal
Conjugate
This STAT5B antibody is un-conjugated
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
158
71
63
34
29
26
17
16
7
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN498182
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN388363 IHC (p) WB Rabbit Ig AA 760-787, C-Term Log in to see Polyclonal
1 ABIN490051 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN2888609 IHC (p) ELISA WB Rabbit IgG AA 697-746 Log in to see Polyclonal
1 ABIN713495 IHC (p) WB HRP Rabbit IgG pSer731 Log in to see Polyclonal
1 ABIN2628853 IHC (p) WB Rabbit IgG AA 767-787 Log in to see Polyclonal
1 ABIN5532151 IHC (p) WB Rabbit Ig Fraction AA 760-787, C-Term Log in to see Polyclonal
1 ABIN713488 IHC (p) WB Biotin Rabbit IgG pSer731 Log in to see Polyclonal
1 ABIN705950 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN2884381 ELISA IHC (p) WB Rabbit IgG pSer731 Log in to see Polyclonal
1 ABIN2476597 IF IHC (p) WB Mouse IgG1 AA 678-788 Log in to see 5D6
1 ABIN713486 IF (p) IHC (p) WB Rabbit IgG pSer731 Log in to see Polyclonal
1 ABIN705943 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN705941 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN3032580 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2893916 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN1938710 IF IP IHC (p) WB Rabbit IgG AA 737-787 Log in to see Polyclonal

Similar anti-STAT5B Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 2 Antibodies 2 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies
Western Blotting (WB) 152 Antibodies 73 Antibodies 66 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 9 Antibodies 13 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 35 Antibodies 17 Antibodies 18 Antibodies
Immunohistochemistry (IHC) 62 Antibodies 32 Antibodies 29 Antibodies

General

Antigen Signal Transducer and Activator of Transcription 5B (STAT5B) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(204), (98), (92), (15), (14), (13), (11), (9), (7), (6), (6), (4), (2), (2), (2), (1)
Host Rabbit
(140), (71)
Clonality
Polyclonal
Conjugate This STAT5B antibody is un-conjugated
(4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(158), (71), (63), (34), (29), (26), (17), (16), (7), (3), (3), (2), (1), (1), (1), (1)
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Product Details anti-STAT5B Antibody

Target Details STAT5B Application Details Handling Images
Specificity This antibody detects endogenous levels of Stat5b protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography using epitope-specific immunogen
Purity > 95 % (by SDS-PAGE)

Target Details STAT5B

Product Details anti-STAT5B Antibody Application Details Handling Images back to top
Antigen
Alternative Name STAT5B (STAT5B Antibody Abstract)
Background Stat5a and Stat5b (signal transducer and activator of transcription 5a and 5b, 96 % homology) undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus where they initiate transcription. Activation of Stat5a via IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin and growth hormones influences proliferation, differentiation and apoptosis in lymphohematopoietic cells. Phosphorylation of Stat5a at Ser 127/Ser 128 and Ser 779 are contigent on ErbB4-mediated activation of Stat5a. Activation of Stat5b via IL-2, IL-4, CSF1 and growth hormones influences TCR signaling, apoptosis, adult mammary gland development and sexual dimorphism of liver gene expression. Stat5b is the major liver-expressed Stat5 form that has been shown to fuse with retinoic acid receptor-α gene in acute promyelocytic leukemias (APLL). Stat5a/b null mice have severely impaired lymphoid development and differentiation.Synonyms: STAT-5B, Signal transducer and activator of transcription 5B
Molecular Weight approx. 90 kDa
Gene ID 6777
NCBI Accession NP_036580
UniProt P51692
Pathways JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation

Application Details

Product Details anti-STAT5B Antibody Target Details STAT5B Handling Images back to top
Application Notes Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-STAT5B Antibody Target Details STAT5B Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (ABIN498182) Immunohistochemistry analyzes of Stat5b antibody in paraffin-embedded human co...
Western Blotting (WB) image for anti-STAT5B antibody (Signal Transducer and Activator of Transcription 5B) (ABIN498182) Western blot analysis of Stat5b antibody in extracts from HeLa cells.