Browse our anti-Thrombopoietin (THPO) Antibodies

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anti-Thrombopoietin Antibodies (THPO)
On are 161 Thrombopoietin (THPO) Antibodies from 26 different suppliers available. Additionally we are shipping Thrombopoietin Proteins (70) and Thrombopoietin Kits (69) and many more products for this protein. A total of 315 Thrombopoietin products are currently listed.
LOC100231762, Mgdf, MKCSF, Ml, Mpllg, THCYT1, Tpo, Tpo1, Tpo2, Tpo3, Tpo4

Most Popular Reactivities for anti-Thrombopoietin (THPO) Antibodies

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anti-Human Thrombopoietin Antibodies:

anti-Mouse (Murine) Thrombopoietin Antibodies:

anti-Rat (Rattus) Thrombopoietin Antibodies:

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Top referenced anti-Thrombopoietin Antibodies

  1. Human Polyclonal Thrombopoietin Primary Antibody for EIA, WB - ABIN359714 : Baker, Su, Hsu, Shi, Zhao, Strande, Fu, Xu, Eis, Komorowski, Jensen, Tweddell, Rafiee, Gross: Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. in Cardiovascular research 2008 (PubMed)
    Show all 3 references for 359714

  2. Dog (Canine) Polyclonal Thrombopoietin Primary Antibody for WB - ABIN2787808 : Baker, Gray, Wright, Fitzsimons, Nimmo, Lowry, Mutrie,: The effect of a pedometer-based community walking intervention "Walking for Wellbeing in the West" on physical activity levels and health outcomes: a 12-week randomized controlled trial. in The international journal of behavioral nutrition and physical activity 2008 (PubMed)
    Show all 2 references for 2787808

  3. Human Monoclonal Thrombopoietin Primary Antibody for EIA, WB - ABIN1109245 : Eissa, Gad, Rabie, El-Gayar: Thrombopoietin level in patients with chronic liver diseases. in Annals of hepatology 2008 (PubMed)
    Show all 2 references for 1109245

  4. Human Monoclonal Thrombopoietin Primary Antibody for FACS, ELISA - ABIN969571 : Graziano, Carone, Panza, Marino, Magini, Romeo, Pession, Seri: Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation. in Blood 2009 (PubMed)
    Show all 2 references for 969571

  5. Human Polyclonal Thrombopoietin Primary Antibody for EIA, Func - ABIN116255 : Xie, Chan, Johnson, Starr, McCarthy, Kapur, Yoder: Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. in Blood 2003 (PubMed)

  6. Human Polyclonal Thrombopoietin Primary Antibody for IF (p), IHC (p) - ABIN1714401 : Nakamura-Ishizu, Takubo, Kobayashi, Suzuki-Inoue, Suda: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. in The Journal of experimental medicine 2015 (PubMed)

  7. Human Polyclonal Thrombopoietin Primary Antibody for WB - ABIN391803 : Kanayasu-Toyoda, Ishii-Watabe, Suzuki, Oshizawa, Yamaguchi: A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Thrombopoietin Interaction Partners

Zebrafish Thrombopoietin (THPO) interaction partners

  1. These studies indicate that the functional role of Tpo in the differentiation of thrombocytes from hematopoietic stem and progenitor cells is well conserved among vertebrate organisms, positing the zebrafish as an excellent model to investigate diseases caused by dysregulated erythro- and thrombo-poietic differentiation.

Human Thrombopoietin (THPO) interaction partners

  1. bone marrow megakaryocytes possess a complete mechanism to synthesize the ECM (show MMRN1 Antibodies) components, and that thrombopoietin is a pivotal regulator of this new function inducing transforming growth factor-b1 (TGF-beta1 (show TGFB1 Antibodies)) release and consequent activation of the downstream pathways, both in vitro and in vivo

  2. High Thrombopoietin expression is associated with immune thrombocytopenia in pregnancy.

  3. Colorectal cancer tumor-initiating cells (TICs) expressing CD110 (show MPL Antibodies), the thrombopoietin (TPO)-binding receptor, mediate liver metastasis. We show that TPO promotes metastasis of CD110 (show MPL Antibodies)+ TICs to the liver by activating lysine degradation.

  4. decreased TPO levels or decreased bone marrow production of platelets may not be a cause of thrombocytopenia in chronic hepatitis C

  5. WASP (show WASL Antibodies), RUNX1 (show RUNX1 Antibodies), and ANKRD26 (show ANKRD26 Antibodies) genes are important for normal TPO signaling and the network underlying thrombopoiesis.

  6. Data suggest that elevated serum level of thrombopoietin may serve as unfavorable marker of stage of multiple myeloma.

  7. The regulation of OCs by TPO highlights a novel therapeutic target for bone loss diseases and may be important to consider in the numerous hematologic disorders associated with alterations in TPO/c-mpl (show MPL Antibodies) signaling

  8. TPO was greatly enhanced in HPT in comparison with ITP (show ITPA Antibodies) patients (958 +/- 659 and 11 +/- 27 pg/ml, p < 0.001). In the ITP (show ITPA Antibodies) group a reverse correlation was detected between TPO and glycocalicin (r = -0.373, p = 0.006).

  9. observations suggest that NRP-1 (show NELL1 Antibodies) is involved in megakaryocytopoiesis through complex formation with PDGFRs, and that NRP-1 (show NELL1 Antibodies)-PDGFR (show PDGFRB Antibodies)-complexes may contribute to effective cellular functions mediated by TPO and PDGF (show PDGFA Antibodies) in megakaryocytic cells

  10. Endocytic AMR (show GPR182 Antibodies) controls TPO expression through Janus kinase 2 (JAK2 (show JAK2 Antibodies)) and the acute phase response signal transducer and activator of transcription 3 (STAT3 (show STAT3 Antibodies)) in vivo and in vitro

Cow (Bovine) Thrombopoietin (THPO) interaction partners

  1. The results demonstrate the possible involvement of locally produced TPO (show TPO Antibodies)/c-MPL (show MPL Antibodies) system as a 'physiological filter' in bovine ovary where they may promote cell selection by inducing proliferation of viable cells and scavenging non-viable cells.

Mouse (Murine) Thrombopoietin (THPO) interaction partners

  1. Thrombopoietin-mediated phosphorylation of STAT5 (show STAT5A Antibodies) triggers its genome-wide relocation to STAT (show STAT1 Antibodies) consensus sites, resulting in loss of a uSTAT5 program that restrains megakaryocytic differentiation and activation of STAT5 (show STAT5A Antibodies)-driven gene expression.

  2. Furthermore, although the contribution of the TPO treated graft to long-term hematological engraftment was reduced, the TPO treated and untreated grafts both contributed significantly to long-term chimerism in vivo.

  3. TPO treatment also promoted the peripheral induction of Foxp3 (show FOXP3 Antibodies)(+) Tregs in conjunction with elevated circulating TGF-beta (show TGFB1 Antibodies) levels.

  4. novel findings about aspects of TPO action on stem cells

  5. Mpl (show MPL Antibodies) expression, but not Tpo, is fundamental in the development of JAK2V617F(+) myeloproliferative neoplasms

  6. Thrombopoietin/MPL (show MPL Antibodies) signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 (show MECOM Antibodies) leukemia.

  7. Megakaryocytes regulate cell cycle quiescence of hematopoietic stem cell through the production of thrombopoietin.

  8. IEX-1 (show IER3 Antibodies) has a role in activation of Erk (show EPHB2 Antibodies) and NF-kB pathways, which affects thrombopoietin-promoted NHEJ DNA repair in hematopoietic stem cells

  9. Findings establish that Clock regulates Thpo and Mpl (show MPL Antibodies) expression in vivo, and demonstrate an important link between the body's circadian timing mechanisms and megakaryopoiesis.

  10. Signal transduction pathway of ERK1/2 (show MAPK1/3 Antibodies) participates in the activation of thrombopoietin in inflammatory injury of BV2 (show DNAH9 Antibodies) cells.

Thrombopoietin (THPO) Antigen Profile

Antigen Summary

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.

Alternative names and synonyms associated with Thrombopoietin (THPO)

  • thrombopoietin (THPO) antibody
  • thrombopoietin (thpo) antibody
  • thrombopoietin (LOC100231762) antibody
  • thrombopoietin (Thpo) antibody
  • thrombopoietin-like (LOC100620258) antibody
  • thrombopoietin-like (LOC100357079) antibody
  • thrombopoietin-like (LOC100855822) antibody
  • LOC100231762 antibody
  • Mgdf antibody
  • MKCSF antibody
  • Ml antibody
  • Mpllg antibody
  • THCYT1 antibody
  • Tpo antibody
  • Tpo1 antibody
  • Tpo2 antibody
  • Tpo3 antibody
  • Tpo4 antibody

Protein level used designations for anti-Thrombopoietin (THPO) Antibodies

thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) , thrombopoietin , MPL ligand , c-mpl ligand , megakaryocyte colony-stimulating factor , megakaryocyte growth and development factor , megakaryocyte stimulating factor , myeloproliferative leukemia virus oncogene ligand , thrombopoietin nirs variant 1 , C-mpl ligand

736549 Pan troglodytes
100189608 Danio rerio
100231762 Taeniopygia guttata
100302539 Felis catus
100582097 Nomascus leucogenys
7066 Homo sapiens
538672 Bos taurus
21832 Mus musculus
81811 Rattus norvegicus
414803 Gallus gallus
607489 Canis lupus familiaris
100726592 Cavia porcellus
101119601 Ovis aries
100620258 Sus scrofa
100357079 Oryctolagus cuniculus
100855822 Canis lupus familiaris
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