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|Application / Reactivity||Human|
|Blocking Antibody (Inhibition)||2 Antibodies|
|Enzyme Immunoassay (EIA)||7 Antibodies|
|Flow Cytometry (FACS)||4 Antibodies|
|Functional Studies (Func)||2 Antibodies|
|Immunochromatography (IC)||6 Antibodies|
|Immunocytochemistry (ICC)||7 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||2 Antibodies|
|Immunohistochemistry (IHC)||13 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies|
|Neutralization (Neut)||9 Antibodies|
|Western Blotting (WB)||85 Antibodies|
|Antigen||Thrombopoietin (THPO) Antibodies|
|Conjugate||This Thrombopoietin antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-Thrombopoietin AntibodyTarget Details Thrombopoietin Application Details Handling References for anti-Thrombopoietin Antibody (ABIN359714) Images
|Specificity||This antibody reacts to Thrombopoietin.|
|Purification||Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the C-term of human THPO.|
Target Details ThrombopoietinProduct Details anti-Thrombopoietin Antibody Application Details Handling References for anti-Thrombopoietin Antibody (ABIN359714) Images back to top
|Alternative Name||Thrombopoietin (THPO Antibody Abstract)|
|Background||Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Synonyms: C-mpl ligand, MGDF, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Myeloproliferative leukemia virus oncogene ligand, THPO|
|Gene ID||7066, 9606|
|Research Area||Cancer, Cell Cycle, Hormones|
Application DetailsProduct Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Handling References for anti-Thrombopoietin Antibody (ABIN359714) Images back to top
ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Application Details References for anti-Thrombopoietin Antibody (ABIN359714) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-Thrombopoietin Antibody (ABIN359714)Product Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Application Details Handling Images back to top
Steinberg, Gilad, Dgany et al.: "Congenital amegakaryocytic thrombocytopenia-3 novel c-MPL mutations and their phenotypic correlations." in: Journal of pediatric hematology/oncology, Vol. 29, Issue 12, pp. 822-5, 2007 (PubMed).
Baker, Su, Hsu et al.: "Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats." in: Cardiovascular research, Vol. 77, Issue 1, pp. 44-53, 2008 (PubMed).
Kanayasu-Toyoda, Ishii-Watabe, Suzuki et al.: "A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33507-14, 2007 (PubMed).
ImagesProduct Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Application Details Handling References for anti-Thrombopoietin Antibody (ABIN359714) back to top