anti-Human Thrombopoietin antibody for Enzyme Immunoassay

Recommended Thrombopoietin Antibody (supplied by: Log in to see )

Antigen
Thrombopoietin (THPO) Antibodies
  • tpo
  • LOC100231762
  • TPO
  • MGDF
  • MKCSF
  • ML
  • MPLLG
  • THCYT1
  • Mgdf
  • Ml
  • Mpllg
  • Tpo
  • Tpo1
  • Tpo2
  • Tpo3
  • Tpo4
  • thrombopoietin
  • thrombopoietin-like
  • THPO
  • thpo
  • LOC100231762
  • Thpo
  • LOC100620258
  • LOC100357079
  • LOC100855822
Epitope
C-Term
6
6
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
Reactivity
Human
147
43
10
4
2
1
1
1
1
1
1
Host
Rabbit
85
59
30
16
Clonality
Polyclonal
Conjugate
This Thrombopoietin antibody is un-conjugated
13
8
5
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
151
111
21
20
11
11
10
6
6
5
3
3
2
2
2
1
1
1
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Catalog No. ABIN359714
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1109245 EIA WB Mouse IgG2a Log in to see 1B11 2
1 ABIN116255 EIA Func WB Goat Log in to see Polyclonal 1
1 ABIN116253 EIA WB Biotin Goat Log in to see Polyclonal
1 ABIN116254 EIA WB Biotin Goat Log in to see Polyclonal
1 ABIN5551484 EIA IHC (p) Rabbit AA 35-50 Log in to see Polyclonal
1 ABIN116256 EIA Func WB Goat Log in to see Polyclonal

General

Antigen Thrombopoietin (THPO) Antibodies
Epitope C-Term
(6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(147), (43), (10), (4), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(85), (59), (30), (16)
Clonality
Polyclonal
Conjugate This Thrombopoietin antibody is un-conjugated
(13), (8), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(151), (111), (21), (20), (11), (11), (10), (6), (6), (5), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Thrombopoietin Antibody

Target Details Thrombopoietin Application Details Handling ProductDetails: References for anti-Thrombopoietin antibody (ABIN359714) Images
Specificity This antibody reacts to Thrombopoietin.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the C-term of human THPO.
Isotype Ig

Target Details Thrombopoietin

Product Details anti-Thrombopoietin Antibody Application Details Handling ProductDetails: References for anti-Thrombopoietin antibody (ABIN359714) Images back to top
Antigen
Alternative Name Thrombopoietin (THPO Antibody Abstract)
Background Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Synonyms: C-mpl ligand, MGDF, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Myeloproliferative leukemia virus oncogene ligand, THPO
Gene ID 7066, 9606
UniProt P40225
Research Area Cancer, Cell Cycle, Hormones
Pathways JAK-STAT Signaling, Hormone Activity

Application Details

Product Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Handling ProductDetails: References for anti-Thrombopoietin antibody (ABIN359714) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Application Details ProductDetails: References for anti-Thrombopoietin antibody (ABIN359714) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-Thrombopoietin antibody (ABIN359714)

Product Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Application Details Handling Images back to top
Background publications

Baker, Su, Hsu, Shi, Zhao, Strande, Fu, Xu, Eis, Komorowski, Jensen, Tweddell, Rafiee, Gross: "Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats." in: Cardiovascular research, Vol. 77, Issue 1, pp. 44-53, 2008

Steinberg, Gilad, Dgany, Krasnov, Zoldan, Laor, Kapelushnik, Gabriel, Churi, Stein, Yaniv, Tamary: "Congenital amegakaryocytic thrombocytopenia-3 novel c-MPL mutations and their phenotypic correlations." in: Journal of pediatric hematology/oncology, Vol. 29, Issue 12, pp. 822-5, 2007

Kanayasu-Toyoda, Ishii-Watabe, Suzuki, Oshizawa, Yamaguchi: "A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33507-14, 2007

Images

Product Details anti-Thrombopoietin Antibody Target Details Thrombopoietin Application Details Handling ProductDetails: References for anti-Thrombopoietin antibody (ABIN359714) back to top
Supplier Images
Western Blotting (WB) image for anti-Thrombopoietin (THPO) (C-Term) antibody (ABIN359714) Western blot analysis of anti-THPO(C-term) Pab in K562 cell line lysates (35ug/lane)....