BAFF ELISA Kit

Catalog No. ABIN4219262

Product Details BAFF ELISA Kit

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 16-1000 pg/mL

Minimum Detection Limit: 16 pg/mL

Application: ELISA

Sample Type: Cell Culture Supernatant, Plasma, Serum

Analytical Method: Quantitative

Specificity: Detects human BAFF.

Cross-Reactivity: Human

No Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Does not detect mouse BAFF.

Sensitivity: 16 pg/mL

Characteristics: BAFF, Soluble (human) Matched Pair Detection Set

Components: 1 vial standard protein (5μg) (lyophilized) [STD] 1 vial coating antibody (120μl) [COAT] 1 vial detection antibody (60μl) [DET] 1 vial streptavidin-HRP (10μg) (lyophilized) [STREP]

Application Details

Plate: Without plate

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Short Term Storage: -20°C
Long Term Storage: -20°C

Expiry Date: 6 months

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: BAFF (TNFSF13B Products)

Synonyms: BAFF ELISA Kit, BLYS ELISA Kit, CD257 ELISA Kit, DTL ELISA Kit, TALL-1 ELISA Kit, TALL1 ELISA Kit, THANK ELISA Kit, TNFSF20 ELISA Kit, ZTNF4 ELISA Kit, BAFF-R ELISA Kit, BAFFR ELISA Kit, BROMIX ELISA Kit, CD268 ELISA Kit, CVID4 ELISA Kit, prolixin ELISA Kit, TNFSF13B ELISA Kit, RGD1561519 ELISA Kit, RGD1560810 ELISA Kit, BLyS ELISA Kit, D8Ertd387e ELISA Kit, zTNF4 ELISA Kit, 2010006P15Rik ELISA Kit, Baffr ELISA Kit, Bcmd ELISA Kit, Bcmd-1 ELISA Kit, Bcmd1 ELISA Kit, Lvis22 ELISA Kit, zgc:172115 ELISA Kit, TNF superfamily member 13b ELISA Kit, TNF receptor superfamily member 13C ELISA Kit, tumor necrosis factor (ligand) superfamily, member 13b ELISA Kit, tumor necrosis factor receptor superfamily, member 13c ELISA Kit, tumor necrosis factor superfamily member 13b ELISA Kit, TNFSF13B ELISA Kit, TNFRSF13C ELISA Kit, Tnfsf13b ELISA Kit, Tnfrsf13c ELISA Kit, tnfsf13b ELISA Kit

Background: BAFF (B cell-activating factor, BLyS, B lymphocyte stimulator, TNFSF13B, TALL-1, CD257), belonging to the TNF family, is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

UniProt: Q5H8V1

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response