Anti-Oxidized Low Density Lipoprotein Antibody ELISA Kit

Catalog No. ABIN5067631

Product Details

Target: Anti-Oxidized Low Density Lipoprotein Antibody

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 37-1200 mU/mL

Minimum Detection Limit: 37 mU/mL

Application: ELISA

Purpose: Enzyme Immunoassay For The Quantitative Determination Of Human IgG Autoantibodies Against Oxidised Low Density Lipoprotein In Serum

Sample Type: Serum

Analytical Method: Quantitative

Specificity: Antibodies against oxLDL,Anti oxidized LDL autoantibodies

Components: plate, assay buffer, wash buffer, standards, cotnrols, conjugate, substrate, stop solution

Material not included: pipettes, tubes, reader

Application Details

Sample Volume: 20 μL

Plate: Pre-coated

Protocol: Oxidized low density lipoprotein (oLDL) is believed to play a critical role in the development and progression of atherosclerosis. Accumulation of oLDL in macrophages and smooth muscle cells causes foam cell formation, an initial step in the disease. Autoantibodies against oxidatively modified LDL can be used as a parameter that consistently mirrors the occurrence of oxidation processes taking place in vivo. In fact, elevated levels of autoantibodies against oLDL have been detected in the blood stream of patients with coronary artery disease. Moreover, recent studies indicate a correlation between autoantibodies against oLDL and the progression of carotid atherosclerosis. Increased serum concentrations of oLAB have also been described in various diseases such as pre-eclampsia and systemic lupus erythematosus. Decreased oLAB titers were observed during septicemia and myocardial infarction.

Assay Precision: Intra-assay (n=8) ≤ 4%, Inter-assay (n=5) ≤ 8%

Restrictions: For Research Use only

Handling

Buffer: ≤ 0.1 % Proclin

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details

Target: Anti-Oxidized Low Density Lipoprotein Antibody

Alternative Name: anti-oxLDL antibody

Target Type: Antibody