The following gene names and symbols are associated with antigen Calreticulin across different species:

calreticulin (CALR), CalReTiculin (crt-1), calreticulin (crc), calreticulin (Crt), calreticulin (crt), calreticulin (CRT), calreticulin (Calr), calreticulin (calr), Calreticulin (Crc), calreticulin (LmjF31.2600), calreticulin (Crc)

Other aliases include:

RO, CRT, SSA, cC1qR, FLJ26680, crc, MGC52637, Crt, crt, Calregulin, zgc:85636, Clr, anon-EST:Liang-2.11, anon-EST:Liang-2.17, anon-EST:fe3D7, clone 2.11, clone 2.17, eth, potp, DmelCG9429, CG9429, ssa, cc1qr, MGC69541, CALR, NV19007

On the protein level the following designations are being used for antigen Calreticulin:

calreticulin – autoantigen Ro – Sicca syndrome antigen A (autoantigen Ro; calreticulin) – CalReTiculin family member (crt-1) – CRP55 – ERp60 – HACBP – OTTMUSP00000025211 – endoplasmic reticulum resident protein 60 – CG9429-PA – Crc-PA – pot pourri – potpourri – anon-fast-evolving-3D7 – CABP3 – CALBP – calregulin – calcium-binding protein 3 – ER-resident chaperone calreticulin

Calreticulin fulfills a number of functions:

DNA binding – androgen receptor binding – calcium ion binding – chaperone binding – complement component C1q binding – integrin binding – mRNA binding – sugar binding – transcription repressor activity – unfolded protein binding – zinc ion binding – protein binding – hormone binding – iron ion binding – metal ion binding – peptide binding – ubiquitin protein ligase binding

Calreticulin is relevant to the following processes:

cell cycle arrest – cortical actin cytoskeleton organization – glucocorticoid receptor signaling pathway – negative regulation of neuron differentiation – negative regulation of retinoic acid receptor signaling pathway – negative regulation of steroid hormone receptor signaling pathway – negative regulation of transcription from RNA polymerase II promoter – negative regulation of translation – peptide antigen assembly with MHC class I protein complex – positive regulation of DNA replication – positive regulation of cell cycle – positive regulation of cell proliferation – positive regulation of phagocytosis – protein export from nucleus – protein maturation by protein folding – protein stabilization – regulation of apoptosis – regulation of meiosis – regulation of transcription, DNA-dependent – senescence – sequestering of calcium ion – defecation – locomotion – multicellular organismal reproductive process – nematode larval development – programmed cell death – protein folding – response to stress – brain morphogenesis – central nervous system development – locomotion involved in locomotory behavior – olfactory behavior – peripheral nervous system development – startle response – cardiac muscle cell differentiation – cellular response to lithium ion – cellular response to organic substance – response to drug – response to estradiol stimulus – response to organic substance – response to testosterone stimulus – spermatogenesis

Locations for Calreticulin:

MHC class I peptide loading complex – cytoplasm – cytosol – endoplasmic reticulum – endoplasmic reticulum lumen – external side of plasma membrane – extracellular region – extracellular space – microsome – nucleus – perinuclear region of cytoplasm – polysome – proteinaceous extracellular matrix – Golgi apparatus – acrosomal vesicle – cell surface – extracellular matrix – soluble fraction – lipid particle – sarcoplasmic reticulum

Source: NCBI Entrez Gene, Gene Ontology