The following gene names and symbols are associated with antigen Cytokeratin 8 across different species:

keratin 8 (KRT8), keratin 18 (KRT18), keratin 8 (Krt8)

Other aliases include:

K8, KO, CK8, CYK8, K2C8, CARD2, K18, CYK18, Card2, EndoA, Krt2-8, Krt-2.8, AA960620, AL022697, AU019895, MGC118110, KRT2-8

On the protein level the following designations are being used for antigen Cytokeratin 8:

keratin 8 – cytokeratin 8 – keratin, type II cytoskeletal 8 – keratin 18 – cytokeratin 18 – cell proliferation-inducing protein 46 – CK-8 – keratin-8 – cytokeratin-8 – cytokeratin endo A – type-II keratin Kb8 – keratin complex 2, basic, gene 8 – K8 – KERA – cytokeratin-A

Cytokeratin 8 fulfills a number of functions:

protein binding – structural molecule activity

Cytokeratin 8 is relevant to the following processes:

apoptosis – cytoskeleton organization – interspecies interaction between organisms – response to other organism – tumor necrosis factor-mediated signaling pathway – Golgi to plasma membrane CFTR protein transport – anatomical structure morphogenesis – cell cycle – negative regulation of apoptosis – cell differentiation involved in embryonic placenta development – cell morphogenesis involved in differentiation – multicellular organismal development – response to hydrostatic pressure

Locations for Cytokeratin 8:

Z disc – cytoplasm – keratin filament – sarcolemma – centriolar satellite – microtubule organizing center – perinuclear region of cytoplasm – costamere – intermediate filament

Source: NCBI Entrez Gene, Gene Ontology