The following gene names and symbols are associated with antigen Metadherin across different species:

metadherin (Mtdh), metadherin (MTDH), metadherin (mtdh)

Other aliases include:

3D3, Lyric, AV353288, 3D3/Lyric, D8Bwg1112e, 2610103J23Rik, AEG1, AEG-1, LYRIC, LYRIC/3D3, MGC75963, MGC137491

On the protein level the following designations are being used for antigen Metadherin:

protein LYRIC – metastasis adhesion protein – lysine-rich CEACAM1 co-isolated protein – 3D3/LYRIC – astrocyte elevated gene-1 protein – LYRIC – metadherin – LYRIC/3D3 – protein LYRIC-like

Metadherin fulfills a number of functions:

NF-kappaB binding – protein binding

Metadherin is relevant to the following processes:

negative regulation of transcription from RNA polymerase II promoter – positive regulation of NF-kappaB transcription factor activity – tight junction assembly

Locations for Metadherin:

cell junction – cytoplasm – endoplasmic reticulum – integral to membrane – membrane – nucleus – tight junction – endoplasmic reticulum membrane – nuclear membrane – nucleolus – perinuclear region of cytoplasm – apical plasma membrane – intercellular canaliculus

Source: NCBI Entrez Gene, Gene Ontology