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TARDBP Protein Lysate (GST tagged)(expressed in E. coli)

Details for Product No. ABIN972641
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Protein
Synonyms TARDBP, TDP43, DKFZp459I2127, tardbp, ALS10, TDP-43, 1190002A23Rik, C85084, Tdp43, wu:fb77f02, wu:fc52g10
Pubmed 1 reference available
Quantity 200 µg
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Catalog No. ABIN972641
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Characteristics This is a recombinant TARDBP protein expressed in E. coli. It is suitable for western blot
Alternative Name TARDBP
Background PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
Molecular Weight 45kDa
Gene ID 23435
NCBI Accession NP_031401, NM_007375
UniProt Q13148
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Hormones, Cytokines
Restrictions For Research Use only
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final concentration is 1 mg/mL.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Kabashi, Valdmanis, Dion et al.: "TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis." in: Nature genetics, Vol. 40, Issue 5, pp. 572-4, 2008 (PubMed).

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