TARDBP Protein Lysate (GST tagged)(expressed in E. coli)

Details for Product No. ABIN972641, Supplier: Log in to see
Protein
  • TARDBP
  • TDP43
  • DKFZp459I2127
  • tardbp
  • ALS10
  • TDP-43
  • 1190002A23Rik
  • C85084
  • Tdp43
  • wu:fb77f02
  • wu:fc52g10
  • TAR DNA binding protein
  • Tardbp protein
  • TAR DNA-binding protein 43-like
  • TARDBP
  • tardbp
  • Tardbp
  • LOC100621383
Protein Species
Human
Species of Lysate
Escherichia coli (E. coli)
Conjugate
GST tag
Application
Western Blotting (WB), Control (Ct)
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Characteristics This is a recombinant TARDBP protein expressed in E. coli. It is suitable for western blot
ProductDetails: Lysate Fraction Whole Cell Lysate
Lysate Type Protein Lysate
Alternative Name TARDBP
Background PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: TDP-43, ALS10

Protein Interaction Partner: ZFAND2B, TARDBP, UBC, SUMO2, STAU1, SUMO3, RNF4, USP8, RBM45, RNF2, LSM6, UBE2E3, GNB2L1, MED6, RPA1, WWOX, RPA3, RPA2, PARK2, EED, BMI1, RBM39, BAG2, RPL23, DDX21, PRPF3, USP10, SART1, RPL14, H1FX, FUBP3, PABPC4, EIF4G3, EIF3I, EIF3H, EIF3C, EIF3B, EIF3A

Protein Size: 414
Molecular Weight 45 kDa
Gene ID 23435
NCBI Accession NM_007375, NP_031401
UniProt Q13148
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Hormones, Cytokines
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of distilled water. Final concentration is 1 mg/mL.
Concentration 1mg/mL
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Background publications Kabashi, Valdmanis, Dion, Spiegelman, McConkey, Vande Velde, Bouchard, Lacomblez, Pochigaeva, Salachas, Pradat, Camu, Meininger, Dupre, Rouleau: "TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis." in: Nature genetics, Vol. 40, Issue 5, pp. 572-4, 2008 (PubMed).