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a genetic variant in the DIP2A gene was associated with increased developmental dyslexia risk in China.
DIP2A could be a cell-surface receptor protein and mediate a FOS down-regulation signal of FRP (show INHBA Proteins). FRP (show INHBA Proteins) bound to DIP2A and CD14 (show NDUFA2 Proteins), and also with proteins of the TGF-beta (show TGFB1 Proteins) superfamily
These data indicate that DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1 (show FSTL1 Proteins).
The protein encoded by this gene may be involved in axon patterning in the central nervous system. This gene is not highly expressed. Several transcript variants encoding different isoforms have been found for this gene.
disco-interacting protein 2 homolog A
, DIP2 disco-interacting protein 2 homolog A (Drosophila)
, DIP2-like protein
, DIP2 homolog A
, disco-interacting protein 2A
, disco interacting protein 2 homolog