Browse our KPNA1 (KPNA1) ELISA Kits

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Karyopherin (Importin) alpha 1 ELISA Kits (KPNA1)
On are 0 Karyopherin (Importin) alpha 1 (KPNA1) ELISA Kits from different suppliers available. A total of 0 KPNA1 products are currently listed.
AW494490, IPOA1, IPOA5, mSRP1, NPI1, QIP2, RCH1, Rch2, SRP1alpha
list all ELISA KIts Gene Name GeneID UniProt
Mouse KPNA1 KPNA1 16646 Q60960
Rat KPNA1 KPNA1 288064  
Human KPNA1 KPNA1 3838 P52292

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More ELISA Kits for KPNA1 Interaction Partners

Mouse (Murine) Karyopherin (Importin) alpha 1 (KPNA1) interaction partners

  1. mTOR (show FRAP1 ELISA Kits) and protein phosphatase 2A catalytically control the constitutive nuclear import of latent STAT1 (show STAT1 ELISA Kits) by KPNA1, which are key modulators of STAT1 (show STAT1 ELISA Kits) expression and apoptosis.

  2. KPNA1 knockdown increased myoblast proliferation.

  3. Importin alpha binding and the nuclear import of myopodin (show SYNPO2 ELISA Kits) are regulated by the serine/threonine phosphorylation-dependent binding of myopodin (show SYNPO2 ELISA Kits) to 14-3-3 (show YWHAQ ELISA Kits). These results establish a novel paradigm for the promotion of nuclear import by 14-3-3 (show YWHAQ ELISA Kits) binding.

  4. PTH1R (show PTH1R ELISA Kits) forms a complex with the transport regulatory proteins, importin alpha(1) and importin beta (show KPNB1 ELISA Kits), and nuclear PTH1R (show PTH1R ELISA Kits) is associated with the nucleoplasm

  5. Here, we show that the expression of importin-alpha subtypes is strictly regulated during neural differentiation of mouse embryonic stem (ES) cells, and that the switching of importin-alpha subtype expression is critical for neural differentiation.

  6. Absence of importin a5 during mouse development does not significantly interfere with neuronal differentiation and brain development.

Cow (Bovine) Karyopherin (Importin) alpha 1 (KPNA1) interaction partners

  1. Bovine ephemeral fever rhabdovirus alpha1 protein binds bovin importin beta1 and importin 7 (show IPO7 ELISA Kits).

Human Karyopherin (Importin) alpha 1 (KPNA1) interaction partners

  1. The authors identified Importin-alpha1 to bind to Coxiella burnetii AnkG and concluded that binding of AnkG to p32 and Importin-alpha1 is essential for its migration into the nucleus.

  2. the crystal structure of the nuclear import adaptor importin-alpha1 bound to the nuclear localization signal (NLS (show ALDH1A2 ELISA Kits)) of EBNA-LP that shows EBNA-LP residues 44-RRVRRR-49 binding to the major NLS (show ALDH1A2 ELISA Kits)-binding site at the P0-P5 positions.

  3. High serum karyopherin alpha 2 levels (>485 microg/mL) correlated with International Federation of Gynecology and Obstetrics stage ( p < 0.0001), lymphatic metastasis ( p = 0.045), overall survival ( p = 0.001), and disease-free progression ( p = 0.006). Serum karyopherin alpha 2 represents a potential diagnostic biomarker for epithelial ovarian carcinoma.

  4. p53 (show TP53 ELISA Kits)/p21Cip1/Waf1 (show CDKN1A ELISA Kits)/p16INK4a may be an important pathway involved in the function of KPNA2 (show KPNA2 ELISA Kits) in tongue squamous cell carcinoma (TSCC) CAL (show FBLIM1 ELISA Kits)-27 cells.

  5. Results demonstrated that radiation-induced dying colorectal cancer cells released considerable amounts of KPNA2 (show KPNA2 ELISA Kits) that induce the maturation and activation of DCs for synergistic antitumor effect of radiation.

  6. These results suggest that the selected aptamers (76 and 72) warrant further study to explore not only their application in cancer diagnosis but also their use as a specific reagent to potentially block KPNA2 (show KPNA2 ELISA Kits)-dependent nuclear transport of macromolecules across the nuclear membrane.

  7. anti-importin alpha1 antibody treatment suppressed the importin alpha1-FGF1 complex formation and ERK1/2 activation, resulting in decreased cell growth. This study provides novel evidence that functional importin alpha1 is located at the cell surface, where it accelerates the proliferation of cancer cells.

  8. The combination of low nuclear and cytoplasmic KPNA2 (show KPNA2 ELISA Kits) expression is associated with adverse outcome in head and neck squamous cell carcinoma treated with radio(chemo)therapy.

  9. provided support for a link between autophagy and epithelial-to-mesenchymal (-like) transition status in WT TP53 (show TP53 ELISA Kits) glioblastoma cells and provided evidence for the signaling pathway (MIR517C-KPNA2 (show KPNA2 ELISA Kits)-cytoplasmic TP53 (show TP53 ELISA Kits)) involved in attenuating autophagy

  10. Suggest that KPNA2 (show KPNA2 ELISA Kits) may play a key role in the inflammation process of rheumatoid arthritis via NF-kappaB (show NFKB1 ELISA Kits) P65 (show GORASP1 ELISA Kits) signal transduction pathway.

KPNA1 Antigen Profile

Antigen Summary

The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination

Alternative names and synonyms associated with KPNA1

  • karyopherin (importin) alpha 1 (Kpna1) Elisa Kit
  • karyopherin alpha 1 (Kpna1) Elisa Kit
  • karyopherin alpha 1 (importin alpha 5) (KPNA1) Elisa Kit
  • karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2) Elisa Kit
  • AW494490 Elisa Kit
  • IPOA1 Elisa Kit
  • IPOA5 Elisa Kit
  • mSRP1 Elisa Kit
  • NPI1 Elisa Kit
  • QIP2 Elisa Kit
  • RCH1 Elisa Kit
  • Rch2 Elisa Kit
  • SRP1alpha Elisa Kit

Protein level used designations for KPNA1

NPI-1 , RAG cohort protein 2 , SRP1-beta , importin alpha-S1 , importin subunit alpha-1 , importin subunit alpha-5 , karyopherin subunit alpha-1 , m-importin-alpha-S1 , nucleoprotein interactor 1 , importin alpha 5 , importin alpha-5 , karyopherin (importin) alpha 1 , karyopherin/importin alpha-1 , RAG cohort 1 , RAG cohort protein 1 , SRP1-alpha , importin alpha 1 , importin alpha 2 , importin subunit alpha-2 , importin-alpha-P1 , karyopherin subunit alpha-2 , pendulin

16646 Mus musculus
288064 Rattus norvegicus
539679 Bos taurus
3838 Homo sapiens
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