Browse our anti-RAB8A (RAB8A) Antibodies

Full name:
anti-RAB8A, Member RAS Oncogene Family Antibodies (RAB8A)
On www.antibodies-online.com are 86 RAB8A, Member RAS Oncogene Family (RAB8A) Antibodies from 19 different suppliers available. Additionally we are shipping RAB8A Proteins (16) and RAB8A Kits (10) and many more products for this protein. A total of 116 RAB8A products are currently listed.
Synonyms:
AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, Mel, Rab8, rab8A, zgc:162699
list all antibodies Gene Name GeneID UniProt
RAB8A 4218 P61006
RAB8A 17274 P55258
RAB8A 117103 P35280

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anti-Human RAB8A Antibodies:

anti-Mouse (Murine) RAB8A Antibodies:

anti-Rat (Rattus) RAB8A Antibodies:

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Top referenced anti-RAB8A Antibodies

  1. Dog (Canine) Monoclonal RAB8A Primary Antibody for IF, IP - ABIN968210 : Bahadoran, Aberdam, Mantoux, Buscà, Bille, Yalman, de Saint-Basile, Casaroli-Marano, Ortonne, Ballotti: Rab27a: A key to melanosome transport in human melanocytes. in The Journal of cell biology 2001 (PubMed)
    Show all 5 references for 968210

  2. Human Polyclonal RAB8A Primary Antibody for FACS, IHC (p) - ABIN1881723 : Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: Construction of a human full-length cDNA bank. in Gene 1995 (PubMed)
    Show all 2 references for 1881723

  3. Human Polyclonal RAB8A Primary Antibody for ELISA, WB - ABIN238664 : Yoshimura, Egerer, Fuchs, Haas, Barr: Functional dissection of Rab GTPases involved in primary cilium formation. in The Journal of cell biology 2007 (PubMed)

  4. Cow (Bovine) Polyclonal RAB8A Primary Antibody for WB - ABIN2792290 : Roland, Kenworthy, Peranen, Caplan, Goldenring: Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3. in Molecular biology of the cell 2007 (PubMed)

More Antibodies against RAB8A Interaction Partners

Human RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. GRAF1 (show ARHGAP26 Antibodies)-mediated removal of Rab8 from the cell surface restricts its activity during protrusion formation, thereby facilitating dynamic adjustment of the polarity axis.

  2. the TNPO1 (show TNPO1 Antibodies)-Rab8-ciliary targeting signals complex mediates selective entry into and retention of cargos within cilia.

  3. Ectopic expression of an N-terminal-truncated ARHGEF10 (show ARHGEF10 Antibodies) mutant led to the generation of large vesicle-like structures containing both Rab6 (show RAB6A Antibodies) and Rab8.

  4. report the design of a bioavailable StRIP3 analogue that harbors two hydrophobic cross-links and exhibits increased binding affinity, combined with robust cellular uptake and extremely high proteolytic stability. Localization experiments reveal that this double-stapled peptide and its target protein Rab8a accumulate in the same cellular compartments

  5. knockdown of another Parkinson's disease (PD) gene, LRRK2 (show LRRK2 Antibodies), which phosphorylates Rab8a, similarly impairs retromer trafficking, secretory autophagy and Golgi-derived vesicle secretion, thus demonstrating converging roles of two PD genes TMEM230 and LRRK2 (show LRRK2 Antibodies) on Rab8a function, and suggesting that retromer and secretory dysfunction play an important role in PD pathogenesis.

  6. Rab8 can induce Rac1- and Tiam1 (show TIAM1 Antibodies)-dependent cortical actin polymerization and focal adhesion disassembly through the proteases MT1-MMP (show MMP14 Antibodies) and calpain, and Rho-GTPase (show RACGAP1 Antibodies)-dependent mechanisms

  7. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (show BIN1 Antibodies)-dynamin (show DNM1 Antibodies) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  8. Further exploration of the NINL (show NINL Antibodies)-associated interactome identifies MICAL3 (show MICAL3 Antibodies), a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.

  9. The small GTPase (show RACGAP1 Antibodies) Rab8 interacts with VAMP-3 (show VAMP3 Antibodies) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  10. the role of Rabin8 (show RAB3IP Antibodies) (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.

Zebrafish RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Cc2d2a (show CC2D2A Antibodies), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.

  2. Data show that elipsa (show TRAF3IP1 Antibodies) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (show RACGAP1 Antibodies), known to localize to cilia.

Mouse (Murine) RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Rab8a and Rab11a (show RAB11A Antibodies) Are Dispensable for Rhodopsin (show RHO Antibodies) Transport in Mouse Photoreceptors

  2. With CRISPR/Cas9-mediated gene editing to stably knock out and recover Rab8a in macrophage cell lines, this study matches Akt (show AKT1 Antibodies) signaling profiles with cytokine outputs, confirming that Rab8a is a novel regulator of the Akt (show AKT1 Antibodies)/mammalian target of rapamycin (mTOR (show FRAP1 Antibodies)) pathway downstream of multiple Toll (show TLR4 Antibodies)-like Receptors.

  3. these results indicate an indispensable role for Rab8A in insulin (show INS Antibodies)-regulated GLUT4 (show SLC2A4 Antibodies) trafficking in C2C12 cells.

  4. Results highlight a novel role of Rab8, downstream of IFT20, in the pathway that regulates T cell receptor (TCR) recycling, through recruiting VAMP-3 and promoting the fusion with the synaptic membrane of endosomes carrying TCR cargoes.

  5. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (show BIN1 Antibodies)-dynamin (show DNM1 Antibodies) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  6. The small GTPase (show RACGAP1 Antibodies) Rab8 interacts with VAMP-3 (show VAMP3 Antibodies) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  7. Rab8a thus controls Wnt (show WNT2 Antibodies) delivery in producing cells and is crucial for Paneth cell maturation.

  8. Rab8a acts as an activator of Fsp27 (show CIDEC Antibodies)-mediated LD fusion and growth.

  9. Simultaneous loss of Rab8a and Rab8b (show RAB8B Antibodies) has little effect on ciliogenesis, whereas additional loss of Rab10 (show RAB10 Antibodies) greatly affects ciliogenesis.

  10. acidosis-induced NBCe1 (show SLC4A4 Antibodies)-A, but not NBCe1 (show SLC4A4 Antibodies)-B/C, trafficking is mediated by Rab8a.

RAB8A Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Alternative names and synonyms associated with RAB8A

  • rab8A protein (rab8A) antibody
  • Rab GTPase (rab8A) antibody
  • RAB8A, member RAS oncogene family (RAB8A) antibody
  • RAB8A, member RAS oncogene family (rab8a) antibody
  • RAB8A, member RAS oncogene family (Rab8a) antibody
  • AA409338 antibody
  • c-mel antibody
  • DDBDRAFT_0206521 antibody
  • DDBDRAFT_0214885 antibody
  • DDB_0206521 antibody
  • DDB_0214885 antibody
  • HSH2D antibody
  • Mel antibody
  • Rab8 antibody
  • rab8A antibody
  • zgc:162699 antibody

Protein level used designations for RAB8A

rab8A protein , hematopoietic SH2 domain containing , ras-related protein Rab-8A , RAB8A, member RAS oncogene family , member RAS oncogene family , Ras-related protein Rab-8A , mel transforming oncogene (RAB8 homolog) , mel transforming oncogene (derived from cell line NK14) , mel transforming oncogene (derived from cell line NK14)- RAB8 homolog , oncogene c-mel , ras-associated protein RAB8 , RAB8, member RAS oncogene family , cell line NK14 derived transforming oncogene

GENE ID SPECIES
553899 Lotus japonicus
8622514 Dictyostelium discoideum AX4
468760 Pan troglodytes
100125217 Xenopus (Silurana) tropicalis
100380328 Salmo salar
4218 Homo sapiens
403773 Canis lupus familiaris
100125881 Bos taurus
571897 Danio rerio
100037230 Xenopus laevis
428352 Gallus gallus
17274 Mus musculus
117103 Rattus norvegicus
100174026 Pongo abelii
101092668 Felis catus
100511006 Sus scrofa
100302063 Ovis aries
100734132 Cavia porcellus
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