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Browse our RAB8A (RAB8A) ELISA Kits

Full name:
RAB8A, Member RAS Oncogene Family ELISA Kits (RAB8A)
On www.antibodies-online.com are 8 RAB8A, Member RAS Oncogene Family (RAB8A) ELISA Kits from 3 different suppliers available. Additionally we are shipping RAB8A Antibodies (86) and RAB8A Proteins (17) and many more products for this protein. A total of 115 RAB8A products are currently listed.
Synonyms:
AA409338, c-mel, DDBDRAFT_0206521, DDBDRAFT_0214885, DDB_0206521, DDB_0214885, HSH2D, Mel, Rab8, rab8A, zgc:162699
list all ELISA KIts Gene Name GeneID UniProt
RAB8A 4218 P61006
RAB8A 17274 P55258
RAB8A 117103 P35280

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RAB8A (RAB8A) ELISA Kits by Reactivity

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Human RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Rab8 can induce Rac1- and Tiam1-dependent cortical actin polymerization and focal adhesion disassembly through the proteases MT1-MMP (show MMP14 ELISA Kits) and calpain, and Rho-GTPase (show RACGAP1 ELISA Kits)-dependent mechanisms

  2. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (show BIN1 ELISA Kits)-dynamin (show DNM1 ELISA Kits) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  3. Further exploration of the NINL-associated interactome identifies MICAL3, a protein known to interact with Rab8 and to play an important role in vesicle docking and fusion.

  4. The small GTPase (show RACGAP1 ELISA Kits) Rab8 interacts with VAMP-3 (show VAMP3 ELISA Kits) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  5. the role of Rabin8 (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined.

  6. DLC3 (show STARD8 ELISA Kits) is recruited to Rab8-positive membrane tubules and is required for the integrity of the Rab8 and Golgi compartments.

  7. Rab8A GTPase (show RACGAP1 ELISA Kits) Ser (show SIGLEC1 ELISA Kits)(111) phosphorylation is not directly regulated by PINK1 in vitro and demonstrate in cells the time course of Ser (show SIGLEC1 ELISA Kits)(111) phosphorylation of Rab8A, 8B and 13 is markedly delayed compared to phosphorylation of Parkin (show PARK2 ELISA Kits) at Ser (show SIGLEC1 ELISA Kits)(65).

  8. Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

  9. High expression of RAB8A is associated with endometrial cancer.

  10. Study established a direct interaction between alpha-synclein and Rab8a and provided unique insights into the molecular mechanisms of alpha-synclein toxicity

Zebrafish RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Cc2d2a (show CC2D2A ELISA Kits), localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion.

  2. Data show that elipsa (show TRAF3IP1 ELISA Kits) encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase (show RACGAP1 ELISA Kits), known to localize to cilia.

Mouse (Murine) RAB8A, Member RAS Oncogene Family (RAB8A) interaction partners

  1. Results highlight a novel role of Rab8, downstream of IFT20, in the pathway that regulates T cell receptor (TCR) recycling, through recruiting VAMP-3 and promoting the fusion with the synaptic membrane of endosomes carrying TCR cargoes.

  2. Data demonstrate that EHBP1L1 links Rab8 and the Bin1 (show BIN1 ELISA Kits)-dynamin (show DNM1 ELISA Kits) complex, which generates membrane curvature and excises the vesicle at the endocytic recycling compartment for apical transport.

  3. The small GTPase (show RACGAP1 ELISA Kits) Rab8 interacts with VAMP-3 (show VAMP3 ELISA Kits) to regulate the delivery of recycling T-cell receptors to the immune synapse.

  4. Rab8a thus controls Wnt (show WNT2 ELISA Kits) delivery in producing cells and is crucial for Paneth cell maturation.

  5. Rab8a acts as an activator of Fsp27 (show CIDEC ELISA Kits)-mediated LD fusion and growth.

  6. Simultaneous loss of Rab8a and Rab8b (show RAB8B ELISA Kits) has little effect on ciliogenesis, whereas additional loss of Rab10 (show RAB10 ELISA Kits) greatly affects ciliogenesis.

  7. acidosis-induced NBCe1 (show SLC4A4 ELISA Kits)-A, but not NBCe1 (show SLC4A4 ELISA Kits)-B/C, trafficking is mediated by Rab8a.

  8. AS160 and Rab8a regulate membrane recruitment of CD36 (show CD36 ELISA Kits).

  9. Cdc42 (show CDC42 ELISA Kits) and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

  10. Rab8a colocalizes with IL-1b (show IL1B ELISA Kits) and LC3 (show MAP1LC3A ELISA Kits) and controls IL-1b (show IL1B ELISA Kits) secretion

RAB8A Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Alternative names and synonyms associated with RAB8A

  • rab8A protein (rab8A) Elisa Kit
  • Rab GTPase (rab8A) Elisa Kit
  • RAB8A, member RAS oncogene family (RAB8A) Elisa Kit
  • RAB8A, member RAS oncogene family (rab8a) Elisa Kit
  • RAB8A, member RAS oncogene family (Rab8a) Elisa Kit
  • AA409338 Elisa Kit
  • c-mel Elisa Kit
  • DDBDRAFT_0206521 Elisa Kit
  • DDBDRAFT_0214885 Elisa Kit
  • DDB_0206521 Elisa Kit
  • DDB_0214885 Elisa Kit
  • HSH2D Elisa Kit
  • Mel Elisa Kit
  • Rab8 Elisa Kit
  • rab8A Elisa Kit
  • zgc:162699 Elisa Kit

Protein level used designations for RAB8A

rab8A protein , hematopoietic SH2 domain containing , ras-related protein Rab-8A , RAB8A, member RAS oncogene family , member RAS oncogene family , Ras-related protein Rab-8A , mel transforming oncogene (RAB8 homolog) , mel transforming oncogene (derived from cell line NK14) , mel transforming oncogene (derived from cell line NK14)- RAB8 homolog , oncogene c-mel , ras-associated protein RAB8 , RAB8, member RAS oncogene family , cell line NK14 derived transforming oncogene

GENE ID SPECIES
553899 Lotus japonicus
8622514 Dictyostelium discoideum AX4
468760 Pan troglodytes
100125217 Xenopus (Silurana) tropicalis
100380328 Salmo salar
4218 Homo sapiens
403773 Canis lupus familiaris
100125881 Bos taurus
571897 Danio rerio
100037230 Xenopus laevis
428352 Gallus gallus
17274 Mus musculus
117103 Rattus norvegicus
100174026 Pongo abelii
101092668 Felis catus
100511006 Sus scrofa
100302063 Ovis aries
100734132 Cavia porcellus
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