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anti-Human SYCP2 Antibodies:
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SYCP2 may contribute to genetic instability during HPV-associated cancer development
SYCP2 and SYCP3 (show SYCP3 Antibodies) proteins function in the specificity of chromatin attachment to the chromosome core
SYCP2 are not required for centromere cohesion at the metaphase-I stage in male germ cells.
SYCP2 is a primary determinant of axial/lateral elements (AEs (show AES Antibodies)/LEs (show FUT3 Antibodies)) and is required for the incorporation of SYCP3 (show SYCP3 Antibodies) into synaptonemal complexes.
The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.
, synaptonemal complex lateral element protein