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anti-Human Nesprin3 Antibodies:
anti-Mouse (Murine) Nesprin3 Antibodies:
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Meta-analysis estimated the relationship between LINC00341 expression and distant metastasis or lymph node metastasis in breast cancer.
nesprin-3 regulates vascular endothelial cell shape, perinuclear cytoskeletal architecture, and important aspects of flow-mediated mechanotransduction.
association with human nesprin-3 appeared to be stronge (show TOR1A Antibodies)r for torsinADeltaE than for torsinA. TorsinA also (show TOR1A Antibodies)associated with the KASH domains of nesprin-1 and -2
Nesprin-3 is critical for the localization of plectin (show PLEC Antibodies) to the nuclear perimeter of Sertoli cells.
Data indicate roles for linkers of nucleus to cytoskeleton (LINC) molecules nesprin2giant and nesprin3, which anchor actin cap fibers to the nucleus.
plectin (show PLEC Antibodies) binds to the integrin alpha6beta4 at the cell surface and to nesprin-3 at the ONM in keratinocytes.
Data support a model in which the actin cytoskeleton influences the binding of plectin (show PLEC Antibodies) dimers to dimers of nesprin-3alpha, which in turn are retained at the nuclear envelope through an interaction with Sun proteins.
Mouse nesprin-3alpha co-immunoprecipitated with torsinA (show TOR1A Antibodies) and this involved the C-terminal region of torsinA (show TOR1A Antibodies) and the KASH domain of nesprin-3alpha.
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
chromosome 14 open reading frame 49
, nuclear envelope spectrin repeat protein 3