Browse our Tonsoku-Like, DNA Repair Protein (NFKBIL2) ELISA Kits

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Tonsoku-Like, DNA Repair Protein ELISA Kits (NFKBIL2)
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Synonyms:
2810439M11Rik, IKBR, im:7145273, nfkbil2, tonsl
list all ELISA KIts Gene Name GeneID UniProt
Human NFKBIL2 NFKBIL2 4796 Q96HA7
Mouse NFKBIL2 NFKBIL2 72749 Q6NZL6
Rat NFKBIL2 NFKBIL2 366953 D4A615

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More ELISA Kits for Tonsoku-Like, DNA Repair Protein Interaction Partners

Human Tonsoku-Like, DNA Repair Protein (NFKBIL2) interaction partners

  1. By specifically regulating RAD51 (show RAD51 ELISA Kits) activity at uncoupled replication forks, MMS22L (show MMS22L ELISA Kits)-TONSL stabilizes perturbed replication forks by promoting replication fork reversal and stimulating their homologous recombination-mediated restart in vivo.

  2. new histones incorporated during DNA replication provide a signature of post-replicative chromatin, read by the human TONSL-MMS22L (show MMS22L ELISA Kits) homologous recombination complex

  3. Common NFKBIL2 polymorphisms are associated with susceptibility to invasive pneumococcal infection.

  4. Results strongly suggest that the Mms22L (show MMS22L ELISA Kits)-Nfkbil2 complex contributes to genome stability by regulating the chromatin state at stalled replication forks.

  5. These results indicate that MMS22L (show MMS22L ELISA Kits) and TONSL are genome caretakers that stimulate the recombination-dependent repair of stalled or collapsed replication forks.

  6. MMS22L (show MMS22L ELISA Kits) and TONSL are required for the maintenance of genome stability.

  7. This study identifies MMS22L (show MMS22L ELISA Kits)-NFKBIL2 as components of the replication stress control pathway.

Tonsoku-Like, DNA Repair Protein (NFKBIL2) Antigen Profile

Antigen Summary

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Alternative names and synonyms associated with Tonsoku-Like, DNA Repair Protein (NFKBIL2)

  • tonsoku-like, DNA repair protein (TONSL) Elisa Kit
  • tonsoku-like, DNA repair protein (Tonsl) Elisa Kit
  • zgc:171416 (zgc:171416) Elisa Kit
  • 2810439M11Rik Elisa Kit
  • IKBR Elisa Kit
  • im:7145273 Elisa Kit
  • nfkbil2 Elisa Kit
  • tonsl Elisa Kit

Protein level used designations for NFKBIL2

I-kappa-B-related protein , NF-kappa-B inhibitor-like protein 2 , ikappaBR , inhibitor of kappa B-related protein , nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 , tonsoku-like protein

GENE ID SPECIES
4796 Homo sapiens
505102 Bos taurus
72749 Mus musculus
366953 Rattus norvegicus
492655 Danio rerio
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