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Seh1l expression is associated with susceptibility to Staphylococcus aureus sepsis.
The assembly of soluble Nup107 (show NUP107 ELISA Kits)-160 complexes into higher order structures occurs only at sites on the chromatin surface that are already covered with the nuclear envelope.
Sec13 (show SEC13 ELISA Kits) stably interacts with Nup96 (show NUP98 ELISA Kits) at the NPC (show NPC1 ELISA Kits) during interphase and the shuttling of Sec13 (show SEC13 ELISA Kits) between the nucleus and the cytoplasm may couple and regulate functions between these two compartments
The protein encoded by this gene is part of a nuclear pore complex, Nup107-160. This protein contains WD repeats and shares 34% amino acid identity with yeast Seh1 and 30% identity with yeast Sec13. All constituents of the Nup107-160 complex, including this protein, specifically localize to kinetochores in mitosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
, nup107-160 subcomplex subunit SEH1
, sec13-like protein
, sec13 like protein
, nucleoporin seh1
, nup107-160 subcomplex subunit seh1