Browse our TACC3 (TACC3) ELISA Kits

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Transforming, Acidic Coiled-Coil Containing Protein 3 ELISA Kits (TACC3)
On are 0 Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) ELISA Kits from different suppliers available. Additionally we are shipping TACC3 Antibodies (63) and TACC3 Proteins (4) and many more products for this protein. A total of 69 TACC3 products are currently listed.
Aint, C86661, ERIC-1, ERIC1, maskin, masking, xmaskin
list all ELISA KIts Gene Name GeneID UniProt
Mouse TACC3 TACC3 21335  
Human TACC3 TACC3 10460 Q9Y6A5
Rat TACC3 TACC3 360962  

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More ELISA Kits for TACC3 Interaction Partners

Mouse (Murine) Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) interaction partners

  1. Tacc3 is required for the proper mitosis of Apc (show APC ELISA Kits)-deficient ISCs (show NFS1 ELISA Kits), and its disruption significantly attenuated the expansion of the crypt domain. In vivo analysis of corresponding mutant mice demonstrated that Tacc3 disruption led to a significant decrease in tumor number and prolonged survival.

  2. Aurora-A kinase (show AURKA ELISA Kits) does not regulate TACC3-chTOG (show CKAP5 ELISA Kits) complex formation, indicating that Aurora-A (show AURKA ELISA Kits) solely functions as a recruitment factor for the TACC3-chTOG (show CKAP5 ELISA Kits) complex to centrosomes and proximal mitotic spindles.

  3. The TACC3 and clathrin were interdependent for spindle recruitment, having to interact in order for either to be recruited to the spindle.

  4. DOCK7 (show DOCK7 ELISA Kits) interaction with TACC3 controls interkinetic nuclear migration and the genesis of neurons from radial glial progenitor cells during cortical development

  5. results show that Tacc3 is a vulnerable component of the spindle assembly in lymphoma cells and is a promising cancer chemotherapy target

  6. Tacc3 is a negative regulator of the Notch (show NOTCH1 ELISA Kits) signaling pathway.

  7. role in hematopoietic stem cell function and interface with p53 (show TP53 ELISA Kits)-regulated apoptosis

  8. the alpha-helix of FOG (show APAF1 ELISA Kits)-ZF3 recognizes a C-terminal portion of the TACC3 coiled-coil.

  9. in addition to spindle assembly, Tacc3 has critical roles in chromosome separation and cytokinesis, and is essential for the mitosis of sclerotome mesenchymal cells during axial formation in mammals.

Human Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) interaction partners

  1. The combination treatment of SNIPER(TACC3) and bortezomib exhibited a synergistic anticancer activity in several cancer cell lines.

  2. Study provides evidence of the significant oncogenic potential of the FGFR3 (show FGFR3 ELISA Kits)-TACC3 fusion protein. The presence of the TACC coiled-coil domain leads to increased and altered levels of FGFR3 (show FGFR3 ELISA Kits) activation, fusion protein phosphorylation, downstream signaling, cellular transformation, proliferation, and viability.

  3. Taken together, these findings uncover a supportive role for TACC3 in PCa (show FLVCR1 ELISA Kits) metastasis, which is mediated by the activation of the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway, suggesting that TACC3 may serve as a prognostic marker in patients with metastatic PCa (show FLVCR1 ELISA Kits).

  4. our observations identify TACC3 as an oncogene (show RAB1A ELISA Kits) of tumor malignancy, as well as a prognostic and motoring biomarker for glioma patients.

  5. The results showed that the expression of TACC3 was downregulated in preeclamptic placentas.

  6. TACC3 overexpression was associated with clinicopathological features of aggressiveness, increased EMT (show ITK ELISA Kits)-related protein expression, and poor survival, suggesting a potential role for TACC3 as a prognostic biomarker and therapeutic target in HCC (show FAM126A ELISA Kits)

  7. Results showed that high level of TACC3 expression was correlated with advanced clinicopathological classifications, and poor prognosis in non-small cell lung cancer patients indicating that TACC3 is a potential prognostic marker.

  8. TACC3 is enriched in hepatocellular carcinoma and down-regulation inhibits the proliferation, clonogenicity, and cancer stem cell-like phenotype of HCC (show FAM126A ELISA Kits) cells

  9. The measurement of TACC3 protein expression may be beneficial for predicting clinical outcomes for gastric cancer patients

  10. TACC3 depletion in human cell lines causes shorter mitotic spindles. co-immunoprecipitation experiments showed reduced binding between TACC3-F543A and Aurora-A (show AURKA ELISA Kits).

Xenopus laevis Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) interaction partners

  1. TACC1 (show TACC1 ELISA Kits) and TACC3 are each required for maintaining normal microtubule growth speed in Xenopus

  2. XTACC3 can induce the recruitment of larger amounts of XMAP215 (show CKAP5 ELISA Kits) by increasing its local concentration, thereby promoting efficient microtubule elongation during mitosis

  3. TACC3 promotes axon outgrowth and regulates microtubule dynamics in multiple embryonic cell types.

  4. Results suggest that phosphorylation of maskin by Aurora-A (show AURKA ELISA Kits) prevents meiosis II proteins from being produced during meiosis I.

  5. Maskin functions in mitotic spindle assembly.

  6. Maskin activity and localization is controlled by differential phosphorylation

  7. Maskin phosphorylation-dephosphorylation also oscillates with the cell cycle and is controlled by the kinase CDK1 and the phosphatase calcineurin

  8. Maskin mRNA is translationally regulated by at least two repressor elements and an activation element.

TACC3 Antigen Profile

Antigen Summary

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells.

Alternative names and synonyms associated with TACC3

  • transforming, acidic coiled-coil containing protein 3 (Tacc3) Elisa Kit
  • transforming, acidic coiled-coil containing protein 3 (TACC3) Elisa Kit
  • transforming, acidic coiled-coil containing protein 3 (tacc3) Elisa Kit
  • Aint Elisa Kit
  • C86661 Elisa Kit
  • ERIC-1 Elisa Kit
  • ERIC1 Elisa Kit
  • maskin Elisa Kit
  • masking Elisa Kit
  • xmaskin Elisa Kit

Protein level used designations for TACC3

ARNT-interacting protein , Arnt interacting protein , transforming acidic coiled-coil-containing protein 3 , transforming acidic coiled coil 3 , CPEB-associated factor Maskin , cytoplasmic polyadenylation element-binding protein-associated factor Maskin

21335 Mus musculus
10460 Homo sapiens
360962 Rattus norvegicus
398145 Xenopus laevis
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