Browse our anti-BAD (BAD) Antibodies

Full name:
anti-BCL2-Associated Agonist of Cell Death Antibodies (BAD)
On www.antibodies-online.com are 993 BCL2-Associated Agonist of Cell Death (BAD) Antibodies from 33 different suppliers available. Additionally we are shipping BAD Kits (52) and BAD Proteins (11) and many more products for this protein. A total of 1132 BAD products are currently listed.
Synonyms:
AI325008, BAD, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04

Most Popular Reactivities for anti-BAD (BAD) Antibodies

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anti-Human BAD Antibodies:

anti-Mouse (Murine) BAD Antibodies:

anti-Rat (Rattus) BAD Antibodies:

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Top referenced anti-BAD Antibodies

  1. Human Polyclonal BAD Primary Antibody for EIA, IHC (p) - ABIN358087 : Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for 358087

  2. Human Polyclonal BAD Primary Antibody for IHC (p), WB - ABIN389520 : Antignani, Youle: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. in Biochemistry 2005 (PubMed)
    Show all 2 references for 389520

  3. Human Polyclonal BAD Primary Antibody for IHC, ELISA - ABIN1532540 : Wang, Rapp, Reed: Bcl-2 targets the protein kinase Raf-1 to mitochondria. in Cell 1997 (PubMed)

  4. Cow (Bovine) Polyclonal BAD Primary Antibody for WB - ABIN2779324 : Xia, Zhang, Du, Pan, Zhao, Sun, Hong, Liu, Fan: miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. in International journal of cancer. Journal international du cancer 2008 (PubMed)

More Antibodies against BAD Interaction Partners

Zebrafish BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad functions as an essential sensitizer and Puma (show BBC3 Antibodies) as an essential activator of IR-induced mitochondrial apoptosis specifically in embryonic neural tissue.

  2. Stage-specific expression of TNFalpha (show TNF Antibodies) regulates bad/bid (show BID Antibodies)-mediated apoptosis and RIP1 (show RALBP1 Antibodies)/ROS (show ROS1 Antibodies)-mediated secondary necrosis in Birnavirus-infected fish cells.

  3. Results indicate that zebrafish BH3-only (show BBC3 Antibodies) proapoptotic protein (BAD) could induce apoptosis in vitro and in vivo and may have biological implications in apoptosis during zebrafish development.

Human BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. The long unstructured region of Bcl-xl (show BCL2L1 Antibodies) modulates its structural dynamics.

  2. Short-term treatment of nascent melanoma tumors with PAK inhibitors that block RhoJ (show RHOJ Antibodies) signaling halts the growth of BRAF (show BRAF Antibodies) mutant melanoma tumors in vivo and induces apoptosis in melanoma cells in vitro via a BAD-dependent mechanism. As up to 50% of BRAF (show BRAF Antibodies) mutant human melanomas express high levels of RhoJ (show RHOJ Antibodies), these studies nominate the RhoJ (show RHOJ Antibodies)-BAD signaling network as a therapeutic vulnerability for fledgling BRAF (show BRAF Antibodies) mutant human tumor

  3. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (show BCL2L1 Antibodies) on the priming of Bax (show BAX Antibodies). As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (show BCL2L1 Antibodies), and of Bcl-2 (show BCL2 Antibodies), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  4. the accumulation of reactive oxygen species (ROS (show ROS1 Antibodies)) in cells expressing JAK2V617F compromises the NHE-1 (show SLC9A1 Antibodies)/Bcl-xL (show BCL2L1 Antibodies) deamidation pathway by repressing NHE-1 (show SLC9A1 Antibodies) upregulation in response to DNA damage. hematopoietic stem cells (HSCs), FOXO3A (show FOXO3 Antibodies) is largely localized within the nuclei despite the presence of JAK2V617F mutation, suggesting that JAK2 (show JAK2 Antibodies)-FOXO (show FOXO3 Antibodies) signaling has a different effect on progenitors compared with stem cells.

  5. These results identify beta3 integrin (show ITGB3 Antibodies) signaling via repression of BAD as an important survival pathway used by breast cancer cells to evade chemotherapy induced stress.

  6. miR (show MLXIP Antibodies)-377 was markedly downregulated in HCC (show FAM126A Antibodies) cell lines and primary human HCC (show FAM126A Antibodies) tissues. The decreased expression of miR (show MLXIP Antibodies)-377 contributes to the upregulation of Bcl-xL (show BCL2L1 Antibodies) expression by targeting its 3'-untranslated region (3'-UTR (show UTS2R Antibodies)).

  7. By the pharmacologic targeting of BCL2 (show BCL2 Antibodies), MCL1 (show MCL1 Antibodies), and BCL-XL (show BCL2L1 Antibodies), we demonstrated that diffuse large B-cell lymphoma can be divided into BCL2 (show BCL2 Antibodies)-dependent and MCL1 (show MCL1 Antibodies)-dependent subgroups with a less pronounced role left for BCL-XL (show BCL2L1 Antibodies).

  8. increased platelet apoptosis and activation as well as reduced expression of Bcl-xL (show BCL2L1 Antibodies), increased expression of Bax (show BAX Antibodies) and caspase-3 (show CASP3 Antibodies) activity were found in platelets after treated with ITP (show ITPA Antibodies) plasma in comparison with control plasma.

  9. These findings demonstrated that Akt (show AKT1 Antibodies) is related to NF-kappaB (show NFKB1 Antibodies) and Bad signaling pathway possibly playing a direct role in the progression of liver cancer. Thus, Akt (show AKT1 Antibodies) might be an important and potential treatment choice for the clinical diagnosis and treatment in the future.

  10. Bh3 domain induced conformational changes in Bcl-Xl (show BCL2L1 Antibodies) revealed by crystal structure and comparative analysis.

Mouse (Murine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad is dispensable for TNF (show TNF Antibodies)-mediated cell death.

  2. Results indicate the downstream targets of insulin (show INS Antibodies), cyclin D1 (show CCND1 Antibodies), BAD, alpha-MHC (show MYH6 Antibodies), and GATA-4 (show GATA4 Antibodies), elucidate a molecular mechanism of insulin (show INS Antibodies) in promoting cell proliferation and differentiation.

  3. our study suggests that Bad and Bmf (show BMF Antibodies) co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.

  4. Results reveal that IKK (show CHUK Antibodies) inhibits TNFalpha (show TNF Antibodies)-induced apoptosis through two distinct but cooperative mechanisms: activation of the survival factor NF-kappaB (show NFKB1 Antibodies) and inactivation of the proapoptotic BH3-only (show BBC3 Antibodies) BAD protein.

  5. RNAi-mediated silencing of STAT1 (show STAT1 Antibodies) in soft tissue sarcoma (STS (show STS Antibodies)) cells was sufficient to increase expression of the apoptotic mediators Fas (show FAS Antibodies) and Bad and to elevate the sensitivity of STS (show STS Antibodies) cells to Fas (show FAS Antibodies)-mediated apoptosis

  6. Tonicity-induced COX-2 (show COX2 Antibodies) expression and PGE2 synthesis in the renal medulla entails phosphorylation and inactivation of the pro-apoptotic protein Bad, thereby counteracting apoptosis in renal medullary epithelial cells.

  7. Caspase-3 (show CASP3 Antibodies) is activated by the BAD-BAX (show BAX Antibodies) cascade resulting in long term depression induction in the hippocampus.

  8. JNK1 (show MAPK8 Antibodies) is required for erythropoietin (show EPO Antibodies)-mediated cell survival through phosphorylation and inactivation of the pro-apoptotic, Bcl-2 (show BCL2 Antibodies) homology domain 3 (BH3)-only (show BBC3 Antibodies) Bcl-associated death protein (Bad).

  9. Bad protein cooperate with bim (show BCL2L11 Antibodies) protein in certain apoptotic responses and in the suppression of g-irradiation-induced thymic lymphoma.(Bad protein)

  10. Data show that loss of Bmf (show BMF Antibodies) reduced the pressure to inactivate p53 (show TP53 Antibodies), whereas Bad deficiency did not, identifying Bmf (show BMF Antibodies) as a novel component of the p53 (show TP53 Antibodies)-independent tumor suppressor pathway triggered by c-Myc (show MYC Antibodies).

Cow (Bovine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

BAD Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Alternative names and synonyms associated with BAD

  • BCL2-antagonist of cell death b (badb) antibody
  • BCL2-associated agonist of cell death (BAD) antibody
  • BCL2-associated agonist of cell death (Bad) antibody
  • AI325008 antibody
  • BAD antibody
  • Bbc2 antibody
  • BCL2L8 antibody
  • fa01b12 antibody
  • wu:fa01b12 antibody
  • wu:fa96d04 antibody

Protein level used designations for BAD

proapoptotic BH3-only protein , BCL2-antagonist of cell death , BCL2-associated agonist of cell death , BCL-X/BCL-2 binding protein , BCL2-antagonist of cell death protein , BCL2-binding component 6 , BCL2-binding protein , bcl-2-binding component 6 , bcl-2-like protein 8 , bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , bcl2-L-8 , Bcl-associated death promoter , bcl-xL/Bcl-2-associated death promoter , Bcl2-antagonist of cell death , bcl-2 associated death agonist , bcl2-associated death promoter

GENE ID SPECIES
58100 Danio rerio
768269 Felis catus
780444 Ovis aries
572 Homo sapiens
12015 Mus musculus
64639 Rattus norvegicus
483763 Canis lupus familiaris
615013 Bos taurus
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