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Browse our anti-BCL2 (BCL2) Antibodies

Full name:
anti-B-Cell CLL/lymphoma 2 Antibodies (BCL2)
On www.antibodies-online.com are 761 B-Cell CLL/lymphoma 2 (BCL2) Antibodies from 40 different suppliers available. Additionally we are shipping BCL2 Kits (32) and BCL2 Proteins (22) and many more products for this protein. A total of 848 BCL2 products are currently listed.
Synonyms:
AW986256, bcl-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, PPP1R50

All available anti-BCL2 Antibodies

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Top referenced anti-BCL2 Antibodies

  1. Human Polyclonal BCL2 Primary Antibody for IF, IHC (p) - ABIN388095 : Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010 (PubMed)
    Show all 19 references for ABIN388095

  2. Human Polyclonal BCL2 Primary Antibody for IP, IHC - ABIN222888 : Giuliani, Mioni, Altavilla, Leone, Bazzani, Minutoli, Bitto, Cainazzo, Marini, Zaffe, Botticelli, Pizzala, Savio, Necchi, Schiöth, Bertolini, Squadrito, Guarini: Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia. in Endocrinology 2006 (PubMed)
    Show all 4 references for ABIN222888

  3. Human Monoclonal BCL2 Primary Antibody for FACS, IHC (fro) - ABIN118990 : Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991 (PubMed)
    Show all 4 references for ABIN118990

  4. Human Monoclonal BCL2 Primary Antibody for FACS - ABIN1105508 : Gallatin, Weissman, Butcher: A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for ABIN1105508

  5. Dog (Canine) Polyclonal BCL2 Primary Antibody for EIA, WB - ABIN782948 : Yu, Xue, Zhou, Li, Zhou: Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. in Phytotherapy research : PTR 2008 (PubMed)
    Show all 2 references for ABIN782948

  6. Human Monoclonal BCL2 Primary Antibody for IHC (fro), IF - ABIN1105504 : Ngan, Chen-Levy, Weiss, Warnke, Cleary: Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. in The New England journal of medicine 1988 (PubMed)
    Show all 2 references for ABIN1105504

  7. Human Monoclonal BCL2 Primary Antibody for FACS, WB - ABIN1105506 : Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: Resistance to Fas-mediated apoptosis in human lung fibroblast. in The European respiratory journal 2002 (PubMed)
    Show all 2 references for ABIN1105506

  8. Human Polyclonal BCL2 Primary Antibody for IHC, ELISA - ABIN1531302 : Cleary, Smith, Sklar: Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. in Cell 1986 (PubMed)

  9. Human Polyclonal BCL2 Primary Antibody for WB - ABIN657744 : Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. in Cancer cell 2010 (PubMed)

  10. Human Polyclonal BCL2 Primary Antibody for EIA, IHC (p) - ABIN356812 : Liu, Zhou, Li, Sun, Lin, Lang, He, Cao, Yan, Wang, Lu, Han, Cao, Zhang, Zeng: Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. in Cancer research 2008 (PubMed)

More Antibodies against BCL2 Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Bcl-2-caspase-9 (show CASP9 Antibodies) apoptosis pathway was clearly activated in the testis of asthmatic mice with the increased expression of apoptosis-related proteins.

  2. Bcl-2 expression in the endothelium plays a significant role during postnatal retinal vascularization, and pathological choroidal but not retinal neovascularization, suggesting vascular bed specific Bcl-2 function in the endothelium

  3. Studied the protein expression of BCL2, FGF-R1, and HSP70 (show HSP70 Antibodies) after short-time magnetic thermoablative tumor treatment using immunohistochemistry in a human BT474 breast cancer mouse xenograft model.

  4. The increased level of Bcl-2 caused by the decrease in miR (show MLXIP Antibodies)-181c protected mitochondrial morphology from the tumour necrosis factor alpha (show TNF Antibodies)-induced apoptosis.

  5. The expression of GRP78 (show HSPA5 Antibodies) and Bcl-2 was significantly higher in astrocytes pretreated with recombinant Shh (show SHH Antibodies). These findings suggest that the expression of Shh (show SHH Antibodies) may inhibit cell death by activating Bcl-2 through a GRP78 (show HSPA5 Antibodies)-dependent pathway.

  6. Knockdown of NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) subunit expression can significantly inhibit the growth of nude mouse Lewis tumour cell xenografts by inducing tumour cell apoptosis and downregulating pro-apoptotic protein Bcl-2 expression.

  7. Studies suggest targeting the BCL-2 family for treating diseases with dysregulated apoptosis.

  8. Deletion of AU-rich elements within the Bcl2 3'UTR (show UTS2R Antibodies) reduces protein expression and B cell survival

  9. The nuclear-penetrating anti-dsDNA autoantibodies could possibly function as a pathogenic factor for lupus nephritis by up-regulating ERK (show EPHB2 Antibodies) activation and Bcl-2 production in mesangial cells.

  10. Enhanced splicing of XBP-1 (show XBP1 Antibodies) was observed in BCL-2 overexpressing cells implicating BCL-2 in the complex regulation of IRE1alpha (show ERN1 Antibodies) activity.

Guinea Pig B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. bcl-2 and bax (show BAX Antibodies) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (show BAX Antibodies)]

Human B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Dysadherin (show FXYD5 Antibodies)-silenced side population cells exhibited reduced expression of Bcl-2 and Bax (show BAX Antibodies) compared with that prior to silencing.

  2. These data indicate that blood BCL2-MBR (show TSPO Antibodies) translocations represent lymphoma precursor clones with malignant potential.

  3. Magnetic iron oxide nanoparticles can induce the autophagy in blood cells by regulating the Beclin 1 (show BECN1 Antibodies)/Bcl-2/Atg14/VPS34 (show PIK3C3 Antibodies) complex.

  4. BCL2 was not an independent prognostic indicator of infiltrating ductal carcinoma of the breast

  5. ABL (show ABL1 Antibodies)-N administration induced apoptosis of PC3 (show PCSK1 Antibodies) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (show BAX Antibodies)/Bcl-2 ratio. Expression of KLF5 (show KLF5 Antibodies), Stat5b (show STAT5B Antibodies) and ICAM-1 (show ICAM1 Antibodies) was significantly downregulated in PC3 (show PCSK1 Antibodies) cells.

  6. miR (show MLXIP Antibodies)-205 suppresses the growth of adrenocortical adenoma SW-13 cells via targeting the anti-apoptotic gene Bcl-2.

  7. Bcl-2 directly interacts with the N-terminus of p62 (show GTF2H1 Antibodies), but not the C-terminus (UBA domain). Bcl-2 affects the affinity of p62 (show GTF2H1 Antibodies) to poly-ubiquitin chains and suppresses the aggregation of poly-ubiquitinated proteins such as mutant huntingtin (show HTT Antibodies).

  8. These observations suggest that HBx may modulate Bcl-2 function in a way that is different from that of the classical BH3-only (show BBC3 Antibodies) proteins.

  9. RBP2 (show KDM5A Antibodies) promotion of overexpression and activation in acute lymphoblastic leukemia development and progression

  10. BCL-2 rs2279115 polymorphism contributes to esophageal squamous cell carcinoma susceptibility in Chinese populations.

Cow (Bovine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Over-expression of STC-1 (show STC1 Antibodies) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (show CASP3 Antibodies) production in the damaged cells. Findings from this study suggest that STC-1 (show STC1 Antibodies) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (show BAX Antibodies) expression.

  3. G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.

  4. role of vascular endothelial growth factor receptor-1 (show FLT1 Antibodies) in Bcl-2 expression

  5. apoptosis-inducing factor (show AIFM1 Antibodies) was expressed in luminal alveolar cells and, in concert with a change in bax (show BAX Antibodies) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  6. mRNA expression of Bax (show BAX Antibodies), Bcl-2, caspase-3 (show CASP3 Antibodies) and-7 cannot be used as a reliable apoptosis detection method.

  7. These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.

Rabbit B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (show BAX Antibodies) and decreasing expression of bcl2.

  2. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (show BAX Antibodies).

  3. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (show TP53 Antibodies) and decrease in the antiapoptotic BCl2 proteins.

  4. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (show CASP3 Antibodies).

  5. Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.

Zebrafish B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. These results suggest a role for mitochondrial p53 (show TP53 Antibodies) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (show BAX Antibodies) and Bcl2.

  2. Zebrafish gene expressions of P53 (show TP53 Antibodies), Bcl-2, Bax (show BAX Antibodies) and caspase-3 (show CASP3 Antibodies) were elevated after exposure with microcystin-LR under different ambient temperatures.

  3. Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (show S1PR1 Antibodies), and ICAM1 (show ICAM1 Antibodies) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.

  4. Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (show COX2 Antibodies) and bcl2, but increased p53 (show TP53 Antibodies) expression.

  5. Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (show NOTCH1 Antibodies) and fish bcl-2, indicating synergy between the Notch (show NOTCH1 Antibodies) pathway and the bcl2-mediated antiapoptotic pathway.

BCL2 Antigen Profile

Antigen Summary

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Alternative names and synonyms associated with BCL2

  • B-cell CLL/lymphoma 2 (BCL2) antibody
  • B-cell CLL/lymphoma 2 (LOC100224888) antibody
  • B cell leukemia/lymphoma 2 (Bcl2) antibody
  • B-cell CLL/lymphoma 2 (Bcl2) antibody
  • B-cell CLL/lymphoma 2 protein (BCL-2) antibody
  • B-cell leukemia/lymphoma 2 (bcl2) antibody
  • AW986256 antibody
  • bcl-2 antibody
  • Bcl2 antibody
  • C430015F12Rik antibody
  • D630044D05Rik antibody
  • D830018M01Rik antibody
  • PPP1R50 antibody

Protein level used designations for BCL2

B-cell lymphoma protein 2 , B-cell leukemia/lymphoma 2 , apoptosis regulator Bcl-2 , B-cell CLL/lymphoma 2 , protein phosphatase 1, regulatory subunit 50 , B cell lymphoma 2 associated oncogene , Bcl2-like protein , BCL2B-cell CLL/lymphoma 2 , PCKBCL2 , Bcl2 , zBlp2

GENE ID SPECIES
738409 Pan troglodytes
100224888 Taeniopygia guttata
12043 Mus musculus
100733337 Cavia porcellus
596 Homo sapiens
24224 Rattus norvegicus
403416 Canis lupus familiaris
493934 Felis catus
100049703 Sus scrofa
281020 Bos taurus
396282 Gallus gallus
100009447 Oryctolagus cuniculus
570772 Danio rerio
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