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Browse our anti-BCL2 (BCL2) Antibodies

Full name:
anti-B-Cell CLL/lymphoma 2 Antibodies (BCL2)
On www.antibodies-online.com are 1059 B-Cell CLL/lymphoma 2 (BCL2) Antibodies from 41 different suppliers available. Additionally we are shipping BCL2 Kits (32) and BCL2 Proteins (22) and many more products for this protein. A total of 1147 BCL2 products are currently listed.
Synonyms:
AW986256, bcl-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, PPP1R50

All available anti-BCL2 Antibodies

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Top referenced anti-BCL2 Antibodies

  1. Human Polyclonal BCL2 Primary Antibody for IF, IHC (p) - ABIN388095 : Zheng, Zhou, Ye, Li, Bai, Zhang: The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells. in World journal of surgical oncology 2010 (PubMed)
    Show all 19 references for ABIN388095

  2. Human Polyclonal BCL2 Primary Antibody for IP, IHC - ABIN222888 : Giuliani, Mioni, Altavilla, Leone, Bazzani, Minutoli, Bitto, Cainazzo, Marini, Zaffe, Botticelli, Pizzala, Savio, Necchi, Schiöth, Bertolini, Squadrito, Guarini: Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia. in Endocrinology 2006 (PubMed)
    Show all 4 references for ABIN222888

  3. Human Monoclonal BCL2 Primary Antibody for FACS, IHC (fro) - ABIN118990 : Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. in Nature 1991 (PubMed)
    Show all 4 references for ABIN118990

  4. Human Monoclonal BCL2 Primary Antibody for FACS - ABIN1105508 : Gallatin, Weissman, Butcher: A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 references for ABIN1105508

  5. Dog (Canine) Polyclonal BCL2 Primary Antibody for EIA, WB - ABIN782948 : Yu, Xue, Zhou, Li, Zhou: Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro. in Phytotherapy research : PTR 2008 (PubMed)
    Show all 2 references for ABIN782948

  6. Human Monoclonal BCL2 Primary Antibody for IHC (fro), IF - ABIN1105504 : Ngan, Chen-Levy, Weiss, Warnke, Cleary: Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. in The New England journal of medicine 1988 (PubMed)
    Show all 2 references for ABIN1105504

  7. Human Monoclonal BCL2 Primary Antibody for FACS, WB - ABIN1105506 : Tanaka, Yoshimi, Maeyama, Hagimoto, Kuwano, Hara: Resistance to Fas-mediated apoptosis in human lung fibroblast. in The European respiratory journal 2002 (PubMed)
    Show all 2 references for ABIN1105506

  8. Human Polyclonal BCL2 Primary Antibody for IHC, WB - ABIN2792106 : Chen, Valencia, Zhong, McColl, Roderick, Bootman, Berridge, Conway, Holmes, Mignery, Velez, Distelhorst: Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. in The Journal of cell biology 2004 (PubMed)

  9. Human Polyclonal BCL2 Primary Antibody for WB - ABIN657744 : Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. in Cancer cell 2010 (PubMed)

  10. Human Polyclonal BCL2 Primary Antibody for EIA, IHC (p) - ABIN356812 : Liu, Zhou, Li, Sun, Lin, Lang, He, Cao, Yan, Wang, Lu, Han, Cao, Zhang, Zeng: Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. in Cancer research 2008 (PubMed)

More Antibodies against BCL2 Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Bcl-2 is an essential regulator in the survival of doublecortin (show DCX Antibodies)-expressing immature neurons.

  2. Results show that the deletion of BCL-2, on its own or in concert with MCL-1 (show MCL1 Antibodies), does not affect platelet production or platelet lifespan.

  3. the expression changes observed within the BCL2 family did not depend on STAT3 (show STAT3 Antibodies) signalling, in line with its initiating role early in the process, but rather appear to result from relief of repression by STAT5 (show STAT5A Antibodies).

  4. Bcl-2-caspase-9 (show CASP9 Antibodies) apoptosis pathway was clearly activated in the testis of asthmatic mice with the increased expression of apoptosis-related proteins.

  5. Bcl-2 expression in the endothelium plays a significant role during postnatal retinal vascularization, and pathological choroidal but not retinal neovascularization, suggesting vascular bed specific Bcl-2 function in the endothelium

  6. Studied the protein expression of BCL2, FGF-R1, and HSP70 (show HSP70 Antibodies) after short-time magnetic thermoablative tumor treatment using immunohistochemistry in a human BT474 breast cancer mouse xenograft model.

  7. The increased level of Bcl-2 caused by the decrease in miR (show MLXIP Antibodies)-181c protected mitochondrial morphology from the tumour necrosis factor alpha (show TNF Antibodies)-induced apoptosis.

  8. The expression of GRP78 (show HSPA5 Antibodies) and Bcl-2 was significantly higher in astrocytes pretreated with recombinant Shh (show SHH Antibodies). These findings suggest that the expression of Shh (show SHH Antibodies) may inhibit cell death by activating Bcl-2 through a GRP78 (show HSPA5 Antibodies)-dependent pathway.

  9. Knockdown of NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) subunit expression can significantly inhibit the growth of nude mouse Lewis tumour cell xenografts by inducing tumour cell apoptosis and downregulating pro-apoptotic protein Bcl-2 expression.

  10. Studies suggest targeting the BCL-2 family for treating diseases with dysregulated apoptosis.

Guinea Pig B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. bcl-2 and bax (show BAX Antibodies) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (show BAX Antibodies)]

Human B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. The potent antitumor activity of RHL (show DDX46 Antibodies) may be mediated through downregulation of Bcl-2 and cyclin D expression and upregulation of BAX (show BAX Antibodies) and Bim (show BCL2L11 Antibodies) expression.

  2. the results indicated that there is a close correlation between the BCL2 rs17757541 C>G polymorphism and coronary artery disease

  3. the BCL2-938C>A and BAX (show BAX Antibodies)-248G>A SNPs significantly associated with platinum-based chemotherapy response, PFS and OS of patients with advanced NSCLC.

  4. MiR-16 (show GDE1 Antibodies) mediated temozolomide-resistance in glioma cells by modulation of apoptosis via targeting Bcl-2

  5. Dual-poly-siRNA carrying glycol chitosan nanoparticles demonstrated successful VEGF (show VEGFA Antibodies)/Bcl2 gene silencing in prostate tumors.

  6. the recently proposed new therapies employing bcl-2 inhibitors prompted the potential use of bax (show BAX Antibodies)/bcl-2 ratio to identify patients putatively resistant to these molecules.

  7. study showed that De novo MYCyBCL2 double-hit BCP (show OPN1SW Antibodies)-ALL is a rare disease that also occurs in pediatric and young adult patients and associated with complex karyotypes and poor prognosis. Younger patients may benefit from intensified chemotherapy.

  8. Results show that PCAF (show KAT2B Antibodies) can induce cell apoptosis by modulating a GLI1 (show GLI1 Antibodies)/Bcl-2/BAX (show BAX Antibodies) axis that in turn suppresses HCC (show FAM126A Antibodies) progression.

  9. Bcl-2 dependent NB cell lines are exquisitely sensitive to ABT-199 . Treatment with ABT-199 displaces Bim (show BCL2L11 Antibodies) from Bcl-2 in NB to activate caspase 3 (show CASP3 Antibodies), confirming the restoration of mitochondrial apoptosis

  10. Co-administration of the mTORC1/TORC2 (show CRTC2 Antibodies) inhibitor INK128 and the Bcl-2/Bcl-xL (show BCL2L1 Antibodies) antagonist ABT-737 kills human myeloid leukemia (show BCL11A Antibodies) cells through Mcl-1 (show MCL1 Antibodies) down-regulation and AKT (show AKT1 Antibodies) inactivation.

Cow (Bovine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Over-expression of STC-1 (show STC1 Antibodies) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (show CASP3 Antibodies) production in the damaged cells. Findings from this study suggest that STC-1 (show STC1 Antibodies) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (show BAX Antibodies) expression.

  3. G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.

  4. role of vascular endothelial growth factor receptor-1 (show FLT1 Antibodies) in Bcl-2 expression

  5. apoptosis-inducing factor (show AIFM1 Antibodies) was expressed in luminal alveolar cells and, in concert with a change in bax (show BAX Antibodies) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  6. mRNA expression of Bax (show BAX Antibodies), Bcl-2, caspase-3 (show CASP3 Antibodies) and-7 cannot be used as a reliable apoptosis detection method.

  7. These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.

Rabbit B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (show BAX Antibodies) and decreasing expression of bcl2.

  2. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (show BAX Antibodies).

  3. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (show TP53 Antibodies) and decrease in the antiapoptotic BCl2 proteins.

  4. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (show CASP3 Antibodies).

  5. Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.

Zebrafish B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. These results suggest a role for mitochondrial p53 (show TP53 Antibodies) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (show BAX Antibodies) and Bcl2.

  2. Zebrafish gene expressions of P53 (show TP53 Antibodies), Bcl-2, Bax (show BAX Antibodies) and caspase-3 (show CASP3 Antibodies) were elevated after exposure with microcystin-LR under different ambient temperatures.

  3. Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (show S1PR1 Antibodies), and ICAM1 (show ICAM1 Antibodies) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.

  4. Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (show COX2 Antibodies) and bcl2, but increased p53 (show TP53 Antibodies) expression.

  5. Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (show NOTCH1 Antibodies) and fish bcl-2, indicating synergy between the Notch (show NOTCH1 Antibodies) pathway and the bcl2-mediated antiapoptotic pathway.

BCL2 Antigen Profile

Antigen Summary

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Alternative names and synonyms associated with BCL2

  • B-cell CLL/lymphoma 2 (BCL2) antibody
  • B-cell CLL/lymphoma 2 (LOC100224888) antibody
  • B cell leukemia/lymphoma 2 (Bcl2) antibody
  • B-cell CLL/lymphoma 2 (Bcl2) antibody
  • B-cell CLL/lymphoma 2 protein (BCL-2) antibody
  • B-cell leukemia/lymphoma 2 (bcl2) antibody
  • AW986256 antibody
  • bcl-2 antibody
  • Bcl2 antibody
  • C430015F12Rik antibody
  • D630044D05Rik antibody
  • D830018M01Rik antibody
  • PPP1R50 antibody

Protein level used designations for BCL2

B-cell lymphoma protein 2 , B-cell leukemia/lymphoma 2 , apoptosis regulator Bcl-2 , B-cell CLL/lymphoma 2 , protein phosphatase 1, regulatory subunit 50 , B cell lymphoma 2 associated oncogene , Bcl2-like protein , BCL2B-cell CLL/lymphoma 2 , PCKBCL2 , Bcl2 , zBlp2

GENE ID SPECIES
738409 Pan troglodytes
100224888 Taeniopygia guttata
12043 Mus musculus
100733337 Cavia porcellus
596 Homo sapiens
24224 Rattus norvegicus
403416 Canis lupus familiaris
493934 Felis catus
100049703 Sus scrofa
281020 Bos taurus
396282 Gallus gallus
100009447 Oryctolagus cuniculus
570772 Danio rerio
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