Browse our anti-BCL2 (BCL2) Antibodies

On www.antibodies-online.com are 1098 B-Cell CLL/lymphoma 2 (BCL2) Antibodies from 41 different suppliers available. Additionally we are shipping BCL2 Kits (91) and BCL2 Proteins (28) and many more products for this protein. A total of 1250 BCL2 products are currently listed.
Synonyms:
AW986256, BCL-2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik, PPP1R50
list all antibodies Gene Name GeneID UniProt
BCL2 596 P10415
BCL2 24224 P49950
BCL2 12043 P10417

Most Popular Reactivities for anti-BCL2 (BCL2) Antibodies

anti-Human BCL2 Antibodies:

anti-Rat (Rattus) BCL2 Antibodies:

anti-Mouse (Murine) BCL2 Antibodies:

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More Antibodies against BCL2 Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. This study provides evidence from transgenic mouse models that Crebbp (show CREBBP Antibodies) deletion results in deficits in B-cell development and can cooperate with Bcl2 overexpression to promote B-cell lymphoma.

  2. an essential role for the binding of BCL2 to BIM (show BCL2L11 Antibodies) in the survival of noncycling NK cells.

  3. LIGHT signalling pathway combined with IFN-gamma (show IFNG Antibodies) induces beta cells apoptosis via an NF-kappaB (show NFKB1 Antibodies)/Bcl2-dependent mitochondrial pathway.

  4. Bcl-2 was highly expressed in tubulointerstitial infiltrates in (NZB x NZW)F1 (NZB/NZW) lupus-prone mice.

  5. The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes

  6. the augmentation of endogenous MTA1 (show MTA1 Antibodies) expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (show ESR1 Antibodies) and BCL2 pathways.

  7. Interestingly, SKPs showed higher protein levels of Bcl-2, Nrf2 (show NFE2L2 Antibodies), and HO-1 (show HMOX1 Antibodies) than FBs (show FBS Antibodies). SKPs exert a beneficial effect on resisting UVB-induced apoptosis, which may be associated with Bcl-2 and Nrf2 (show NFE2L2 Antibodies) upregulation.

  8. Bcl-2 is an essential regulator in the survival of doublecortin (show DCX Antibodies)-expressing immature neurons.

  9. Results show that the deletion of BCL-2, on its own or in concert with MCL-1 (show MCL1 Antibodies), does not affect platelet production or platelet lifespan.

  10. the expression changes observed within the BCL2 family did not depend on STAT3 (show STAT3 Antibodies) signalling, in line with its initiating role early in the process, but rather appear to result from relief of repression by STAT5 (show STAT5A Antibodies).

Guinea Pig B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. bcl-2 and bax (show BAX Antibodies) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (show BAX Antibodies)]

Human B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. MYC (show MYC Antibodies) and BCL2 genetic alterations were profiled using next-generation sequencing and high-resolution single nucleotide polymorphism array in 347 de novo diffuse large B-cell lymphoma cases.

  2. findings suggest that expression of cFLIPL regulates the basal interaction of Bcl-2 with Beclin-1 (show BECN1 Antibodies) and substantiates p53 (show TP53 Antibodies) dependent ubiquitination of Beclin-1 (show BECN1 Antibodies) during autophagic stress to determine the fate of cell death or survival.

  3. Our findings suggest that RACK1 (show GNB2L1 Antibodies) promotes proliferation and radioresistance in ESCC cells by activating the AKT (show AKT1 Antibodies) pathway, upregulating Bcl-2 expression and downregulating protein levels of Bim (show BCL2L11 Antibodies). Our study fills in gaps in the field of RACK1 (show GNB2L1 Antibodies) and radiation resistance and may provide new possibilities for improving strategies of radiotherapy in esophageal cancer.

  4. Western blot analysis and quantitative real-time polymerase chain reaction demonstrated reduced expression of pri-miR (show MLXIP Antibodies)-211, miR (show MLXIP Antibodies)-211, TRPM1 (show TRPM1 Antibodies), and MLANA (show MLANA Antibodies) levels, after Bcl-2 overexpression, associated with increased expression of well-known miR (show MLXIP Antibodies)-211 target genes.

  5. this study elucidated mechanisms of BCL2 overexpression and association of this survival pathway with the BCR (show BCR Antibodies)/BTK (show BTK Antibodies) signaling pathway in MCL (show FH Antibodies), and revealed the role of BTK (show BTK Antibodies) in noncanonical NF-kappaB (show NFKB1 Antibodies) activation, which also promotes cancer cell survival.

  6. Follicular lymphoma with MYC (show MYC Antibodies) and BCL2 translocations, so-called double-hit follicular lymphoma (DH-FL), is part of the spectrum of double-hit high-grade lymphoma.

  7. we propose that the existing controversy reflects the diversity of links between Bcl-2 proteins and Ca(2 (show CA2 Antibodies)+) signaling, as certainly not all targets or mechanisms will be operative in every cell type and every condition.

  8. Overview of the pleiotropic functions of BCL2 mediated by its physical binding interaction with other proteins and the various ways BCL2 mutations would affect the normal function of the cell leading to the development of diffuse large B-cell lymphomas (review).

  9. Diffuse large B-cell lymphoma with concurrent high MYC (show MYC Antibodies) and BCL2 expression shows evidence of active B-cell receptor signaling

  10. Case Reports: BCL2 gene translocations are a recurrent feature of a distinct subset of histiocytic sarcomas that are associated with follicular lymphoma.

Cow (Bovine) B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. Over-expression of STC-1 (show STC1 Antibodies) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (show CASP3 Antibodies) production in the damaged cells. Findings from this study suggest that STC-1 (show STC1 Antibodies) plays a protective role in intestinal cells through an antioxidant mechanism.

  2. BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (show BAX Antibodies) expression.

  3. G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.

  4. role of vascular endothelial growth factor receptor-1 (show FLT1 Antibodies) in Bcl-2 expression

  5. apoptosis-inducing factor (show AIFM1 Antibodies) was expressed in luminal alveolar cells and, in concert with a change in bax (show BAX Antibodies) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  6. mRNA expression of Bax (show BAX Antibodies), Bcl-2, caspase-3 (show CASP3 Antibodies) and-7 cannot be used as a reliable apoptosis detection method.

  7. These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.

Rabbit B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. excessive apoptosis does occur in acetabular cartilage with developmental dislocations of the hip, and is positively correlated with high caspase-3 (show CASP3 Antibodies) expression as well as low Bcl-2 expression.

  2. These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax (show BAX Antibodies) ratio through a mechanism involving protein kinase C (show PKC Antibodies).

  3. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (show BAX Antibodies) and decreasing expression of bcl2.

  4. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (show BAX Antibodies).

  5. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (show TP53 Antibodies) and decrease in the antiapoptotic BCl2 proteins.

  6. Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (show CASP3 Antibodies).

  7. Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.

Zebrafish B-Cell CLL/lymphoma 2 (BCL2) interaction partners

  1. These results suggest a role for mitochondrial p53 (show TP53 Antibodies) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (show BAX Antibodies) and Bcl2.

  2. Zebrafish gene expressions of P53 (show TP53 Antibodies), Bcl-2, Bax (show BAX Antibodies) and caspase-3 (show CASP3 Antibodies) were elevated after exposure with microcystin-LR under different ambient temperatures.

  3. Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (show S1PR1 Antibodies), and ICAM1 (show ICAM1 Antibodies) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.

  4. Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (show COX2 Antibodies) and bcl2, but increased p53 (show TP53 Antibodies) expression.

  5. Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (show NOTCH1 Antibodies) and fish bcl-2, indicating synergy between the Notch (show NOTCH1 Antibodies) pathway and the bcl2-mediated antiapoptotic pathway.

BCL2 Antigen Profile

Antigen Summary

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

Alternative names and synonyms associated with BCL2

  • B-cell CLL/lymphoma 2 (BCL2) antibody
  • B-cell CLL/lymphoma 2 (Bcl2) antibody
  • B-cell CLL/lymphoma 2 (LOC100224888) antibody
  • B cell leukemia/lymphoma 2 (Bcl2) antibody
  • B-cell leukemia/lymphoma 2 (bcl2) antibody
  • B-cell leukemia/lymphoma 2-like (LOC100359045) antibody
  • B-cell CLL/lymphoma 2 protein (BCL-2) antibody
  • AW986256 antibody
  • BCL-2 antibody
  • Bcl2 antibody
  • C430015F12Rik antibody
  • D630044D05Rik antibody
  • D830018M01Rik antibody
  • PPP1R50 antibody

Protein level used designations for BCL2

apoptosis regulator Bcl-2 , protein phosphatase 1, regulatory subunit 50 , B cell lymphoma 2 associated oncogene , B-cell leukemia/lymphoma 2 , Bcl2-like protein , PCKBCL2 , BCL2B-cell CLL/lymphoma 2 , B-cell lymphoma protein 2 , Bcl2 , zBlp2 , B-cell CLL/lymphoma 2

GENE ID SPECIES
596 Homo sapiens
24224 Rattus norvegicus
396282 Gallus gallus
493934 Felis catus
738409 Pan troglodytes
100224888 Taeniopygia guttata
100049703 Sus scrofa
12043 Mus musculus
570772 Danio rerio
403416 Canis lupus familiaris
281020 Bos taurus
100733337 Cavia porcellus
100359045 Oryctolagus cuniculus
100009447 Oryctolagus cuniculus
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