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anti-Human BCL2 antibody for Immunohistochemistry (Frozen Sections)

Recommended BCL2 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 2 (BCL2) Antibodies
  • AW986256
  • bcl-2
  • BCL-2
  • Bcl-2
  • Bcl2
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • PPP1R50
Epitope
AA 41-54
164
72
60
55
50
44
24
24
22
19
17
15
14
14
14
14
14
13
12
12
7
4
4
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
958
225
167
40
22
16
15
7
4
3
2
2
1
1
Host
Mouse
519
509
19
6
2
2
2
Clonality
Monoclonal
Conjugate
This BCL2 antibody is un-conjugated
46
46
40
37
24
23
19
14
14
13
13
13
13
13
13
13
12
12
12
12
6
6
6
6
6
6
6
2
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
760
340
317
293
289
280
252
176
145
74
42
12
11
10
10
5
3
1
1
1
1
1
Supplier
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Catalog No. ABIN1105504
$ 313.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008879846 ABIN118990 FACS IHC (fro) IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see 100 4
0.0008879846 ABIN967312 IHC (fro) FACS IF IP WB Armenian Hamster IgG Log in to see 6C8 13
0.0008879846 ABIN967311 IHC (fro) FACS IF IP WB Hamster IgG Log in to see 6C8 13
0.0008879846 ABIN967321 IHC (f) IHC (fro) FACS WB Mouse IgG1 AA 41-54 Log in to see 7
0.0008879846 ABIN967322 IHC (f) IHC (fro) FACS WB Mouse IgG1 AA 41-54 Log in to see 7
0.0008879846 ABIN781707 IHC (fro) FACS IF IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see Bcl2-100
0.0008879846 ABIN1105507 IHC (fro) IHC (p) Rabbit IgG Log in to see E17 6
0.0008879846 ABIN1491491 ICC IHC (fro) IHC (p) WB Mouse IgG1 AA 41-54 Log in to see BL-2
0.0008879846 ABIN3044481 ICC IHC (fro) IHC (p) WB Mouse IgG1 AA 41-54 Log in to see Bcl-2-100
0.0008879846 ABIN126981 IHC (fro) IP WB Rabbit N-Term Log in to see Polyclonal
0.0008879846 ABIN957155 IHC (fro) IHC (p) IP WB Rabbit AA 41-54 Log in to see Polyclonal
0.0008879846 ABIN957159 IHC (fro) IHC (p) IP WB Rabbit AA 61-76 Log in to see Polyclonal
0.0008879846 ABIN609189 ICC IHC (fro) IF IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see
0.0008879846 ABIN957156 IHC (fro) IHC (p) IP WB Rabbit AA 41-54 Log in to see Polyclonal
0.0008879846 ABIN2477599 IHC (fro) FACS IHC (p) IP WB Mouse IgG1 Log in to see 100 4
0.0008879846 ABIN4283367 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 1
0.0008879846 ABIN609190 IHC (fro) IHC (p) Mouse IgG1, kappa Log in to see
0.0008879846 ABIN4283369 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 2
0.0008879846 ABIN4283401 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Allophycocyanin Mouse IgG1 kappa Log in to see 8C8
0.0008879846 ABIN4283399 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 647 Mouse IgG1 kappa Log in to see 8C8

Top referenced anti-BCL2 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-BCL2 Antibodies

Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Dot Blot (DB) 42 Antibodies
ELISA 310 Antibodies
Enzyme Immunoassay (EIA) 9 Antibodies
Flow Cytometry (FACS) 275 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 10 Antibodies
Immunocytochemistry (ICC) 162 Antibodies
Immunofluorescence (IF) 274 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 62 Antibodies
Immunohistochemistry (IHC) 272 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 143 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 310 Antibodies
Immunoprecipitation (IP) 228 Antibodies
Immunostaining (ISt) 1 Antibodies
Intracellular Staining (ICS) 3 Antibodies

General

Antigen B-Cell CLL/lymphoma 2 (BCL2) Antibodies
Epitope AA 41-54
(164), (72), (60), (55), (50), (44), (24), (24), (22), (19), (17), (15), (14), (14), (14), (14), (14), (13), (12), (12), (7), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(958), (225), (167), (40), (22), (16), (15), (7), (4), (3), (2), (2), (1), (1)
Host Mouse
(519), (509), (19), (6), (2), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL2 antibody is un-conjugated
(46), (46), (40), (37), (24), (23), (19), (14), (14), (13), (13), (13), (13), (13), (13), (13), (12), (12), (12), (12), (6), (6), (6), (6), (6), (6), (6), (2), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(760), (340), (317), (293), (289), (280), (252), (176), (145), (74), (42), (12), (11), (10), (10), (5), (3), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-BCL2 Antibody

Target Details BCL2 Application Details Handling References for anti-BCL2 Antibody (ABIN1105504) Images
Specificity This antibody reacts to BCL2.
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to residues 41-54pf the bcl-2 protein, conjugated to thyroglobulin.
Clone BL-2
Isotype IgG1

Target Details BCL2

Product Details anti-BCL2 Antibody Application Details Handling References for anti-BCL2 Antibody (ABIN1105504) Images back to top
Antigen
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t(14,18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
Gene ID 596
NCBI Accession NP_000624
UniProt P10415
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-BCL2 Antibody Target Details BCL2 Handling References for anti-BCL2 Antibody (ABIN1105504) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details References for anti-BCL2 Antibody (ABIN1105504) Images back to top
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-BCL2 Antibody (ABIN1105504)

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling Images back to top
Background publications

Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death." in: Nature, Vol. 348, Issue 6299, pp. 334-6, 1991

Ngan, Chen-Levy, Weiss, Warnke, Cleary: "Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation." in: The New England journal of medicine, Vol. 318, Issue 25, pp. 1638-44, 1988

Images

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling References for anti-BCL2 Antibody (ABIN1105504) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 41-54) (ABIN1105504) anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody