You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human BCL2 antibody for Immunohistochemistry (Frozen Sections)

Recommended BCL2 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 2 (BCL2) Antibodies
  • AW986256
  • Bcl-2
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • PPP1R50
  • BCL-2
  • bcl-2
  • Bcl2
  • B-cell CLL/lymphoma 2
  • B cell leukemia/lymphoma 2
  • B-cell CLL/lymphoma 2 protein
  • B-cell leukemia/lymphoma 2
  • BCL2
  • LOC100224888
  • Bcl2
  • BCL-2
  • bcl2
Epitope
AA 41-54
164
73
64
59
41
33
25
25
24
18
15
15
15
14
13
13
13
11
8
7
6
5
5
5
5
5
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
988
251
211
54
28
22
18
18
5
4
4
3
2
2
2
2
Host
Mouse
539
510
19
6
2
2
2
Clonality
Monoclonal
Conjugate
This BCL2 antibody is un-conjugated
47
46
42
37
24
23
21
15
14
13
13
13
13
13
13
13
12
12
12
7
7
7
6
6
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
781
368
358
306
305
289
226
185
168
81
40
13
13
12
12
11
9
4
3
1
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN1105504
$ 313.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN118990 FACS IHC (fro) IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see 100 4
1 ABIN967312 IHC (fro) FACS IF IP WB Armenian Hamster IgG Log in to see 6C8 13
1 ABIN3044481 ICC IHC (fro) IHC (p) WB Mouse IgG1 AA 41-54 Log in to see Bcl-2-100
1 ABIN967311 IHC (fro) FACS IF IP WB Hamster IgG Log in to see 6C8 13
1 ABIN967321 IHC (f) IHC (fro) FACS WB Mouse IgG1 AA 41-54 Log in to see 7
1 ABIN967322 IHC (f) IHC (fro) FACS WB Mouse IgG1 AA 41-54 Log in to see 7
1 ABIN781707 IHC (fro) FACS IF IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see Bcl2-100
1 ABIN1105507 IHC (fro) IHC (p) Rabbit IgG Log in to see E17 6
1 ABIN1491491 ICC IHC (fro) IHC (p) WB Mouse IgG1 AA 41-54 Log in to see BL-2
1 ABIN4283367 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 1
1 ABIN4283369 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 2
1 ABIN4283388 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa Log in to see 8C8
1 ABIN4283406 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB HRP Mouse IgG1 kappa Log in to see 8C8
1 ABIN126981 IHC (fro) IP WB Rabbit N-Term Log in to see Polyclonal
1 ABIN957155 IHC (fro) IHC (p) IP WB Rabbit AA 41-54 Log in to see Polyclonal
1 ABIN957159 IHC (fro) IHC (p) IP WB Rabbit AA 61-76 Log in to see Polyclonal
1 ABIN4283394 ELISA ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see 8C8
1 ABIN1491493 ICC IHC (fro) IHC (p) IP WB Sepharose Mouse IgG1 AA 41-54 Log in to see BL-2
1 ABIN4283411 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 350 Mouse IgG1 kappa Log in to see 8C8
1 ABIN4283508 FACS ICC IF IHC (fro) IHC (p) WB DyLight 650 Mouse IgG AA 41-54 Log in to see 100-D5-124

Top referenced anti-BCL2 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-BCL2 Antibodies

Application / Reactivity Human
Cell Culture (CC) 1 Antibodies
Cellular Assay (CA) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 12 Antibodies
Dot Blot (DB) 40 Antibodies
ELISA 343 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 12 Antibodies
Flow Cytometry (FACS) 289 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 9 Antibodies
Immunocytochemistry (ICC) 171 Antibodies
Immunofluorescence (IF) 291 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 12 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 68 Antibodies
Immunohistochemistry (IHC) 278 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 166 Antibodies

General

Antigen B-Cell CLL/lymphoma 2 (BCL2) Antibodies
Epitope AA 41-54
(164), (73), (64), (59), (41), (33), (25), (25), (24), (18), (15), (15), (15), (14), (13), (13), (13), (11), (8), (7), (6), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(988), (251), (211), (54), (28), (22), (18), (18), (5), (4), (4), (3), (2), (2), (2), (2)
Host Mouse
(539), (510), (19), (6), (2), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BCL2 antibody is un-conjugated
(47), (46), (42), (37), (24), (23), (21), (15), (14), (13), (13), (13), (13), (13), (13), (13), (12), (12), (12), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(781), (368), (358), (306), (305), (289), (226), (185), (168), (81), (40), (13), (13), (12), (12), (11), (9), (4), (3), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-BCL2 Antibody

Target Details BCL2 Application Details Handling References for anti-BCL2 Antibody (ABIN1105504) Images
Specificity This antibody reacts to BCL2.
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to residues 41-54pf the bcl-2 protein, conjugated to thyroglobulin.
Clone BL-2
Isotype IgG1

Target Details BCL2

Product Details anti-BCL2 Antibody Application Details Handling References for anti-BCL2 Antibody (ABIN1105504) Images back to top
Antigen
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t(14,18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
Gene ID 596
NCBI Accession NP_000624
UniProt P10415
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-BCL2 Antibody Target Details BCL2 Handling References for anti-BCL2 Antibody (ABIN1105504) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details References for anti-BCL2 Antibody (ABIN1105504) Images back to top
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-BCL2 Antibody (ABIN1105504)

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling Images back to top
Background publications

Hockenbery, Nuñez, Milliman, Schreiber, Korsmeyer: "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death." in: Nature, Vol. 348, Issue 6299, pp. 334-6, 1991

Ngan, Chen-Levy, Weiss, Warnke, Cleary: "Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation." in: The New England journal of medicine, Vol. 318, Issue 25, pp. 1638-44, 1988

Images

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling References for anti-BCL2 Antibody (ABIN1105504) back to top
Supplier Images
Western Blotting (WB) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 41-54) (ABIN1105504) anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody