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anti-Human BCL2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended BCL2 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 2 (BCL2) Antibodies
  • AW986256
  • Bcl-2
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • PPP1R50
  • BCL-2
  • bcl-2
  • Bcl2
  • B-cell CLL/lymphoma 2
  • B cell leukemia/lymphoma 2
  • B-cell CLL/lymphoma 2 protein
  • B-cell leukemia/lymphoma 2
  • BCL2
  • LOC100224888
  • Bcl2
  • BCL-2
  • bcl2
Epitope
N-Term
165
74
62
57
50
44
25
25
22
19
18
15
15
15
15
14
14
13
12
12
7
5
4
4
4
4
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
978
233
174
41
22
16
16
7
4
3
2
2
1
Host
Rabbit
531
515
21
6
2
2
2
Clonality
Polyclonal
Conjugate
This BCL2 antibody is un-conjugated
46
46
40
37
24
23
19
14
13
13
13
13
13
13
13
12
12
12
12
7
7
7
6
6
6
6
6
6
6
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
749
382
337
312
309
302
220
198
168
81
42
13
12
11
10
9
5
3
1
1
1
1
1
Supplier
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Catalog No. ABIN499427
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.081278 ABIN4283376 ELISA FACS ICC IF IHC IHC (p) Mouse IgG1 Log in to see 8E12 1
12.081278 ABIN4283367 IHC IHC (fro) IHC (p) IP WB Rabbit Log in to see Polyclonal 1
12.081278 ABIN950625 EIA IF IHC (p) WB Rabbit IgG AA 145-157, Internal Region Log in to see Polyclonal
12.081278 ABIN4283388 FACS ICC IF IHC IHC (fro) IHC (p) WB Mouse IgG1 kappa Log in to see 8C8
12.081278 ABIN498979 IF IHC (p) WB Rabbit Log in to see Polyclonal
12.081278 ABIN213746 IF IHC (p) WB Rabbit IgG Ser70 Log in to see Polyclonal
12.081278 ABIN250623 IHC (p) IHC WB Mouse IgG1 kappa Log in to see 124
12.081278 ABIN337080 FACS IF IHC (p) ELISA WB Mouse IgG1 AA 41-54 Log in to see
1 ABIN1105504 IHC (fro) IF IHC (p) WB Mouse IgG1 AA 41-54 Log in to see BL-2 2
1 ABIN118990 FACS IHC (fro) IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see 100 4
1 ABIN356812 EIA IHC (p) IP WB Rabbit Ig BH3 Domain Log in to see Polyclonal 1
1 ABIN388095 IF IHC (p) WB Rabbit Ig AA 75-110, BH3 Domain Log in to see Polyclonal 19
1 ABIN197204 IF IHC (p) WB Rabbit Ser70 Log in to see Polyclonal 4
1 ABIN197202 IF IHC (p) WB Rabbit AA 54-58 Log in to see Polyclonal 4
1 ABIN271996 IF IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN265326 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN707156 IF (p) IHC (p) WB Rabbit IgG AA 169-211 Log in to see Polyclonal 5
1 ABIN4283360 IHC IHC (p) IP WB Rabbit Log in to see Polyclonal 6
1 ABIN781707 IHC (fro) FACS IF IHC (p) IP WB Mouse IgG1 AA 41-54 Log in to see Bcl2-100
1 ABIN1105507 IHC (fro) IHC (p) Rabbit IgG Log in to see E17 6

Top referenced anti-BCL2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-BCL2 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 60 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 31 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies
Functional Studies (Func) 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 26 Antibodies
Immunofluorescence (IF) 50 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 52 Antibodies
Immunohistochemistry (IHC) 58 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 30 Antibodies
Western Blotting (WB) 145 Antibodies
Cellular Assay (CA) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 12 Antibodies
Dot Blot (DB) 42 Antibodies

General

Antigen B-Cell CLL/lymphoma 2 (BCL2) Antibodies
Epitope N-Term
(165), (74), (62), (57), (50), (44), (25), (25), (22), (19), (18), (15), (15), (15), (15), (14), (14), (13), (12), (12), (7), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(978), (233), (174), (41), (22), (16), (16), (7), (4), (3), (2), (2), (1)
Host Rabbit
(531), (515), (21), (6), (2), (2), (2)
Clonality
Polyclonal
Conjugate This BCL2 antibody is un-conjugated
(46), (46), (40), (37), (24), (23), (19), (14), (13), (13), (13), (13), (13), (13), (13), (12), (12), (12), (12), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(749), (382), (337), (312), (309), (302), (220), (198), (168), (81), (42), (13), (12), (11), (10), (9), (5), (3), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-BCL2 Antibody

Target Details BCL2 Application Details Handling References for anti-BCL2 Antibody (ABIN499427) Images
Specificity Bcl-2 antibody was raised against a peptide corresponding to 15 amino acids near the N-terminus of human Bcl-2.
Purification Ion exchange chromatography
Immunogen Murine Bcl-2 (N-Terminus) Peptide
Isotype IgG

Target Details BCL2

Product Details anti-BCL2 Antibody Application Details Handling References for anti-BCL2 Antibody (ABIN499427) Images back to top
Antigen
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis (reviewed in 2 and 3). These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis (4). It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad (5 for review). Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer (4,6).Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
Gene ID 596
UniProt P10415
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-BCL2 Antibody Target Details BCL2 Handling References for anti-BCL2 Antibody (ABIN499427) Images back to top
Application Notes ELISA. Western Blot: Bcl-2 antibody can be used for detection of Bcl-2 at 1 to 2 μg/mL. Immunohistochemistry: Bcl-2 antibody can also detect Bcl-2 by immunohistochemistry at 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details References for anti-BCL2 Antibody (ABIN499427) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-BCL2 Antibody (ABIN499427)

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling Images back to top
Background publications

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, 2000

Images

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling References for anti-BCL2 Antibody (ABIN499427) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (N-Term) (ABIN499427) Immunohistochemical staining of human kidney using AP30128PU-N Bcl-2 antibody at 2 μg...
Western Blotting (WB) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (N-Term) (ABIN499427) Western blot analysis of Bcl-2 in Daudi cell lysates with AP30128PU-N Bcl-2 antibody ...