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anti-Rat (Rattus) BCL2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended BCL2 Antibody (supplied by: Log in to see )

Antigen
B-Cell CLL/lymphoma 2 (BCL2) Antibodies
  • AW986256
  • bcl-2
  • BCL-2
  • Bcl-2
  • Bcl2
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • PPP1R50
Epitope
AA 145-157, Internal Region
76
71
53
49
48
44
23
23
19
17
15
14
14
13
13
13
13
12
12
9
7
4
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
673
199
150
17
9
7
4
3
2
2
1
1
Host
Rabbit
493
240
19
5
2
2
2
Clonality
Polyclonal
Conjugate
This BCL2 antibody is un-conjugated
38
33
28
24
19
14
11
10
7
6
6
6
6
6
6
3
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
480
275
241
144
138
138
112
67
49
42
33
11
10
9
8
8
5
1
1
1
1
1
Supplier
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Catalog No. ABIN950625
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN707156 IF (p) IHC (p) WB Rabbit IgG AA 169-211 Log in to see Polyclonal 4
0.00089488085 ABIN683428 IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 43-93, pSer70 Log in to see Polyclonal 1
0.00089488085 ABIN271996 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN265326 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN2857047 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.00089488085 ABIN317971 IHC (p) IP WB Rabbit pSer70 Log in to see Polyclonal
0.00089488085 ABIN756622 IF (p) IHC (p) WB Rabbit IgG pThr129 Log in to see Polyclonal
0.00089488085 ABIN1732255 IF IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
0.00089488085 ABIN707158 IHC (p) WB Biotin Rabbit IgG AA 169-211 Log in to see Polyclonal
0.00089488085 ABIN707165 IHC (p) WB HRP Rabbit IgG AA 169-211 Log in to see Polyclonal
0.00089488085 ABIN683430 IHC (p) WB Biotin Rabbit IgG AA 43-93, pSer70 Log in to see Polyclonal
0.00089488085 ABIN683437 IHC (p) WB HRP Rabbit IgG AA 43-93, pSer70 Log in to see Polyclonal
0.00089488085 ABIN1700450 IHC (p) WB Biotin Rabbit IgG pSer87 Log in to see Polyclonal
0.00089488085 ABIN1711467 IHC (p) WB HRP Rabbit IgG pSer87 Log in to see Polyclonal
0.00089488085 ABIN756631 IHC (p) WB HRP Rabbit IgG pThr129 Log in to see Polyclonal
0.00089488085 ABIN756624 IHC (p) WB Biotin Rabbit IgG pThr129 Log in to see Polyclonal
0.00089488085 ABIN1713952 IF (p) IHC (p) WB Rabbit IgG pSer87 Log in to see Polyclonal

Top referenced anti-BCL2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-BCL2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 27 Antibodies 55 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 7 Antibodies
Flow Cytometry (FACS) 25 Antibodies 32 Antibodies
Functional Studies (Func) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 21 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 45 Antibodies
Immunohistochemistry (IHC) 32 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies
Immunoprecipitation (IP) 15 Antibodies
Intracellular Staining (ICS) 5 Antibodies
Western Blotting (WB) 82 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies

General

Antigen B-Cell CLL/lymphoma 2 (BCL2) Antibodies
Epitope AA 145-157, Internal Region
(76), (71), (53), (49), (48), (44), (23), (23), (19), (17), (15), (14), (14), (13), (13), (13), (13), (12), (12), (9), (7), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(673), (199), (150), (17), (9), (7), (4), (3), (2), (2), (1), (1)
Host Rabbit
(493), (240), (19), (5), (2), (2), (2)
Clonality
Polyclonal
Conjugate This BCL2 antibody is un-conjugated
(38), (33), (28), (24), (19), (14), (11), (10), (7), (6), (6), (6), (6), (6), (6), (3), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(480), (275), (241), (144), (138), (138), (112), (67), (49), (42), (33), (11), (10), (9), (8), (8), (5), (1), (1), (1), (1), (1)
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Product Details anti-BCL2 Antibody

Target Details BCL2 Application Details Handling Images
Specificity This antibody detects endogenous levels of total BCL-2 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide from Human BCL-2. Epitope: Internal
Isotype IgG

Target Details BCL2

Product Details anti-BCL2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity. Also interacts with APAF1, RAF1, TP53BP2, BBC3, BCL2L1 and BNIPL.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
Gene ID 596
NCBI Accession NP_000624
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-BCL2 Antibody Target Details BCL2 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-BCL2 Antibody Target Details BCL2 Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 145-157) (ABIN950625) Immunofluorescence analysis of HepG2 cells, using BCL2 Antibody . The picture on the ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 145-157) (ABIN950625) Formalin-Fixed, Paraffin-Embedded Human Kidney, Tubules stained with BCL2
Western Blotting (WB) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 145-157) (ABIN950625) Western blot analysis of extracts from K562 cells, using BCL2 Antibody . The lane on ...