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Rat (Rattus) BCL2 ELISA Kit for Sandwich ELISA - ABIN416111
Salama, Abdulla, AlRashdi, Ismail, Alkiyumi, Golbabapour: Hepatoprotective effect of ethanolic extract of Curcuma longa on thioacetamide induced liver cirrhosis in rats. in BMC complementary and alternative medicine 2013
Show all 6 references for ABIN416111
Human BCL2 ELISA Kit for Sandwich ELISA - ABIN414423
Sasaki, Udaka, Tsunoda, Yamamoto, Tsuji, Oyamada, Oguchi, Mizutani: Analysis of p53 and miRNA expression after irradiation of glioblastoma cell lines. in Anticancer research 2012
Show all 2 references for ABIN414423
Mouse (Murine) BCL2 ELISA Kit for Sandwich ELISA - ABIN415401
Nakano, Marui, Muranaka, Masumoto, Noma, Tabata, Ido, Tsubouchi, Ikeda, Sakata: Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin. in Interactive cardiovascular and thoracic surgery 2014
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Bcl-2-caspase-9 (show CASP9 ELISA Kits) apoptosis pathway was clearly activated in the testis of asthmatic mice with the increased expression of apoptosis-related proteins.
Bcl-2 expression in the endothelium plays a significant role during postnatal retinal vascularization, and pathological choroidal but not retinal neovascularization, suggesting vascular bed specific Bcl-2 function in the endothelium
Studied the protein expression of BCL2, FGF-R1, and HSP70 (show HSP70 ELISA Kits) after short-time magnetic thermoablative tumor treatment using immunohistochemistry in a human BT474 breast cancer mouse xenograft model.
The increased level of Bcl-2 caused by the decrease in miR (show MLXIP ELISA Kits)-181c protected mitochondrial morphology from the tumour necrosis factor alpha (show TNF ELISA Kits)-induced apoptosis.
The expression of GRP78 (show HSPA5 ELISA Kits) and Bcl-2 was significantly higher in astrocytes pretreated with recombinant Shh (show SHH ELISA Kits). These findings suggest that the expression of Shh (show SHH ELISA Kits) may inhibit cell death by activating Bcl-2 through a GRP78 (show HSPA5 ELISA Kits)-dependent pathway.
Knockdown of NF-kappaB (show NFKB1 ELISA Kits) p65 (show NFkBP65 ELISA Kits) subunit expression can significantly inhibit the growth of nude mouse Lewis tumour cell xenografts by inducing tumour cell apoptosis and downregulating pro-apoptotic protein Bcl-2 expression.
Studies suggest targeting the BCL-2 family for treating diseases with dysregulated apoptosis.
Deletion of AU-rich elements within the Bcl2 3'UTR (show UTS2R ELISA Kits) reduces protein expression and B cell survival
The nuclear-penetrating anti-dsDNA autoantibodies could possibly function as a pathogenic factor for lupus nephritis by up-regulating ERK (show EPHB2 ELISA Kits) activation and Bcl-2 production in mesangial cells.
Enhanced splicing of XBP-1 (show XBP1 ELISA Kits) was observed in BCL-2 overexpressing cells implicating BCL-2 in the complex regulation of IRE1alpha (show ERN1 ELISA Kits) activity.
bcl-2 and bax (show BAX ELISA Kits) were expressed strongly in denervated guinea-pig facial muscle. [bcl-2; bax (show BAX ELISA Kits)]
Dysadherin (show FXYD5 ELISA Kits)-silenced side population cells exhibited reduced expression of Bcl-2 and Bax (show BAX ELISA Kits) compared with that prior to silencing.
These data indicate that blood BCL2-MBR (show TSPO ELISA Kits) translocations represent lymphoma precursor clones with malignant potential.
Magnetic iron oxide nanoparticles can induce the autophagy in blood cells by regulating the Beclin 1 (show BECN1 ELISA Kits)/Bcl-2/Atg14/VPS34 (show PIK3C3 ELISA Kits) complex.
BCL2 was not an independent prognostic indicator of infiltrating ductal carcinoma of the breast
ABL (show ABL1 ELISA Kits)-N administration induced apoptosis of PC3 (show PCSK1 ELISA Kits) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (show BAX ELISA Kits)/Bcl-2 ratio. Expression of KLF5 (show KLF5 ELISA Kits), Stat5b (show STAT5B ELISA Kits) and ICAM-1 (show ICAM1 ELISA Kits) was significantly downregulated in PC3 (show PCSK1 ELISA Kits) cells.
miR (show MLXIP ELISA Kits)-205 suppresses the growth of adrenocortical adenoma SW-13 cells via targeting the anti-apoptotic gene Bcl-2.
Bcl-2 directly interacts with the N-terminus of p62 (show GTF2H1 ELISA Kits), but not the C-terminus (UBA domain). Bcl-2 affects the affinity of p62 (show GTF2H1 ELISA Kits) to poly-ubiquitin chains and suppresses the aggregation of poly-ubiquitinated proteins such as mutant huntingtin (show HTT ELISA Kits).
These observations suggest that HBx may modulate Bcl-2 function in a way that is different from that of the classical BH3-only (show BBC3 ELISA Kits) proteins.
RBP2 (show KDM5A ELISA Kits) promotion of overexpression and activation in acute lymphoblastic leukemia development and progression
BCL-2 rs2279115 polymorphism contributes to esophageal squamous cell carcinoma susceptibility in Chinese populations.
Over-expression of STC-1 (show STC1 ELISA Kits) up-regulated Bcl-2 protein expression and slightly down-regulated caspase-3 (show CASP3 ELISA Kits) production in the damaged cells. Findings from this study suggest that STC-1 (show STC1 ELISA Kits) plays a protective role in intestinal cells through an antioxidant mechanism.
BoHV-5 replication apparently modulates BCL-2 expression and gene transcription, enhancing production of virus progeny, but does not increase Bax (show BAX ELISA Kits) expression.
G3139, a BCL-2 antisesnse oligonucleotide is a promising candidate for treatment of patients with imatinib-resistant Ph-positive leukemia.
role of vascular endothelial growth factor receptor-1 (show FLT1 ELISA Kits) in Bcl-2 expression
apoptosis-inducing factor (show AIFM1 ELISA Kits) was expressed in luminal alveolar cells and, in concert with a change in bax (show BAX ELISA Kits) protein to bcl-2 protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
mRNA expression of Bax (show BAX ELISA Kits), Bcl-2, caspase-3 (show CASP3 ELISA Kits) and-7 cannot be used as a reliable apoptosis detection method.
These results propose an additional mechanism whereby resveratrol may exert its cardioprotective effects and suggest a key role for Bcl-2 in the resveratrol anti-apoptotic action, especially in disrupting peroxynitrite-triggered mitochondrial pathway.
Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax (show BAX ELISA Kits) and decreasing expression of bcl2.
Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 and increased expression of Bax (show BAX ELISA Kits).
Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 (show TP53 ELISA Kits) and decrease in the antiapoptotic BCl2 proteins.
Isoflurane delayed preconditioning can inhibit the apoptosis of myocardium by up-regulating the expression of Bcl-2 and down-regulating the activation of caspase-3 (show CASP3 ELISA Kits).
Data show that the damaged electron transport chain leads to bcl-2 depletion and MPT opening.
These results suggest a role for mitochondrial p53 (show TP53 ELISA Kits) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax (show BAX ELISA Kits) and Bcl2.
Zebrafish gene expressions of P53 (show TP53 ELISA Kits), Bcl-2, Bax (show BAX ELISA Kits) and caspase-3 (show CASP3 ELISA Kits) were elevated after exposure with microcystin-LR under different ambient temperatures.
Analysis using clinical biopsy specimens revealed autophagy and increased levels of BCL2, S1P1 (show S1PR1 ELISA Kits), and ICAM1 (show ICAM1 ELISA Kits) in human T-lymphoblastic lymphoma compared with T-lymphoblastic leukemia.
Real-time RT-PCR revealed acetaminophen treatment of zebrafish embryos decreased the expression of cox2 (show COX2 ELISA Kits) and bcl2, but increased p53 (show TP53 ELISA Kits) expression.
Leukemia onset was dramatically accelerated in transgenic fish overexpressing human Notch1 (show NOTCH1 ELISA Kits) and fish bcl-2, indicating synergy between the Notch (show NOTCH1 ELISA Kits) pathway and the bcl2-mediated antiapoptotic pathway.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
B-cell lymphoma protein 2
, B-cell leukemia/lymphoma 2
, apoptosis regulator Bcl-2
, B-cell CLL/lymphoma 2
, protein phosphatase 1, regulatory subunit 50
, B cell lymphoma 2 associated oncogene
, Bcl2-like protein
, BCL2B-cell CLL/lymphoma 2