anti-Human BRAF antibody for Immunofluorescence (fixed cells)

Recommended BRAF Antibody (supplied by: Log in to see )

Antigen
V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) Antibodies
  • B-Raf
  • braf1
  • rafb1
  • b-raf1
  • sierrabraf
  • BRAF
  • 9930012E13Rik
  • AA120551
  • AA387315
  • AA473386
  • B-raf
  • Braf-2
  • Braf2
  • C230098H17
  • C87398
  • D6Ertd631e
  • Braf
  • HYPT11
  • SME
  • Sm-E
  • B-RAF1
  • BRAF1
  • NS7
  • RAFB1
  • C-RMIL
  • RMIL
  • v-raf murine sarcoma viral oncogene homolog B
  • v-raf murine sarcoma viral oncogene homolog B1
  • Braf transforming gene
  • Braf transforming gene, related sequence 1
  • small nuclear ribonucleoprotein polypeptide E
  • braf
  • BRAF
  • LOC100219601
  • Braf
  • Braf-rs1
  • SNRPE
Reactivity
Human, Mouse (Murine)
406
84
69
13
10
4
4
3
1
1
1
1
Host
Mouse
309
93
3
2
Clonality
Monoclonal
Conjugate
This BRAF antibody is un-conjugated
20
20
20
17
17
17
3
3
3
3
3
3
3
3
3
3
3
Application
ELISA, Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (IHC), Western Blotting (WB)
267
209
144
78
71
45
39
22
11
8
5
4
1
1
1
Supplier
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Catalog No. ABIN1842978
$ 398.75
Plus shipping costs $45.00

General

Antigen V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) Antibodies
Reactivity Human, Mouse (Murine)
(406), (84), (69), (13), (10), (4), (4), (3), (1), (1), (1), (1)
Host Mouse
(309), (93), (3), (2)
Clonality
Monoclonal
Conjugate This BRAF antibody is un-conjugated
(20), (20), (20), (17), (17), (17), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application ELISA, Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (IHC), Western Blotting (WB)
(267), (209), (144), (78), (71), (45), (39), (22), (11), (8), (5), (4), (1), (1), (1)
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Product Details anti-BRAF Antibody

Target Details BRAF Application Details Handling Images
Purification Ascitic fluid containing 0.03% sodium azide.
Immunogen Purified recombinant fragment of human BRAF expressed in E. coli.
Isotype IgG1

Target Details BRAF

Product Details anti-BRAF Antibody Application Details Handling Images back to top
Antigen
Alternative Name BRAF (BRAF Antibody Abstract)
Background BRAF: v-raf murine sarcoma viral oncogene homolog B1, also known as BRAF1, RAFB1, B-RAF1, FLJ95109.Entrez Protein NP_004324.It is the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway.B-Raf contains three consensus Akt phosphorylationsites (Ser364, Ser428, and Thr439).B-Raf is a key regulatory molecule of the mitogen-activated protein kinase kinase (MEK), it has a long amino-terminal region,the region is essential for homo-dimerization of B-Raf and hetero-dimerization of B-Raf and c-Raf at the plasma membrane, followed by phosphorylation of Thr118 in the amino-terminal B-Raf-specific region.Notably, in calcium ionophore-stimulated HeLa cells, B-Raf could propagate signals to MEK under the basal level of GTP-Ras.Expression of Raf-B is highly restricted with highestlevels in the cerebrum and testes and defects in braf are involved in a wide range of cancers.The BRAF gene mutation is frequently detected in papillary thyroid carcinoma,melanocytic nevi, primary cutaneous melanomas and colorectal cancers.
Molecular Weight 87 kDa
Pathways MAPK Signaling, RTK Signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy

Application Details

Product Details anti-BRAF Antibody Target Details BRAF Handling Images back to top
Restrictions For Research Use only

Handling

Product Details anti-BRAF Antibody Target Details BRAF Application Details Images back to top
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.

Images

Product Details anti-BRAF Antibody Target Details BRAF Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (ABIN1842978) anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody
Immunocytochemistry (ICC) image for anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (ABIN1842978) anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (Image 2)
Western Blotting (WB) image for anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (ABIN1842978) anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (Image 3)