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anti-Mouse (Murine) BRAF antibody for Immunofluorescence

Recommended BRAF Antibody (supplied by: Log in to see )

Antigen
V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) Antibodies
  • B-Raf
  • braf1
  • rafb1
  • b-raf1
  • sierrabraf
  • BRAF
  • 9930012E13Rik
  • AA120551
  • AA387315
  • AA473386
  • B-raf
  • Braf-2
  • Braf2
  • C230098H17
  • C87398
  • D6Ertd631e
  • Braf
  • HYPT11
  • SME
  • Sm-E
  • B-RAF1
  • BRAF1
  • NS7
  • RAFB1
  • C-RMIL
  • RMIL
  • v-raf murine sarcoma viral oncogene homolog B
  • v-raf murine sarcoma viral oncogene homolog B1
  • Braf transforming gene
  • Braf transforming gene, related sequence 1
  • small nuclear ribonucleoprotein polypeptide E
  • braf
  • BRAF
  • LOC100219601
  • Braf
  • Braf-rs1
  • SNRPE
Reactivity
Human, Mouse (Murine)
405
59
48
6
4
1
1
1
Host
Mouse
311
91
3
2
Clonality
Monoclonal
Conjugate
This BRAF antibody is un-conjugated
20
20
20
17
17
17
3
3
3
3
3
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
256
213
147
82
52
43
39
16
10
5
4
2
1
1
1
Supplier
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Catalog No. ABIN1105489
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.710068 ABIN2163048 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2470813 IF IHC ELISA WB Mouse IgG1 Log in to see 1H12
1 ABIN2962049 IF IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1583592 IF IHC WB Mouse IgG1 Log in to see 1H12
1 ABIN4889013 ELISA IF WB Rabbit Val600Glu-Mutant Log in to see Polyclonal
1 ABIN4889012 ELISA IF WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN1842978 ICC IF IHC ELISA WB Mouse IgG1 Log in to see
1 ABIN1575079 IF IHC ELISA WB Mouse Log in to see

Top referenced anti-BRAF antibody for Immunofluorescence

Similar anti-BRAF Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 28 Antibodies 211 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 11 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 5 Antibodies
Immunofluorescence (IF) 9 Antibodies 42 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 24 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 42 Antibodies
Dot Blot (DB) 82 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 16 Antibodies
Functional Studies (Func) 1 Antibodies

General

Antigen V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) Antibodies
Reactivity Human, Mouse (Murine)
(405), (59), (48), (6), (4), (1), (1), (1)
Host Mouse
(311), (91), (3), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This BRAF antibody is un-conjugated
(20), (20), (20), (17), (17), (17), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(256), (213), (147), (82), (52), (43), (39), (16), (10), (5), (4), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-BRAF Antibody

Target Details BRAF Application Details Handling References for anti-BRAF Antibody (ABIN1105489) Images
Specificity Recognizes Threonine Protein Kinase BRAF
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Ascites
Clone 1H12
Isotype IgG1

Target Details BRAF

Product Details anti-BRAF Antibody Application Details Handling References for anti-BRAF Antibody (ABIN1105489) Images back to top
Antigen
Background BRAF: v-raf murine sarcoma viral oncogene homolog B1, also known as BRAF1, RAFB1, B-RAF1, FLJ95109 is the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway. B-Raf contains three consensus Akt phosphorylationsites (Ser364, Ser428, and Thr439). B-Raf is a key regulatory molecule of the mitogen-activated protein kinase kinase (MEK), it has a long amino-terminal region,the region is essential for homo-dimerization of B-Raf and hetero-dimerization of B-Raf and c-Raf at the plasma membrane, followed by phosphorylation of Thr118 in the amino-terminal B-Raf-specific region. Notably, in calcium ionophore-stimulated HeLa cells, B-Raf could propagate signals to MEK under the basal level of GTP-Ras. Expression of Raf-B is highly restricted with highestlevels in the cerebrum and testes and defects in braf are involved in a wide range of cancers. The BRAF gene mutation is frequently detected in papillary thyroid carcinoma,melanocytic nevi, primary cutaneous melanomas and colorectal cancers.Synonyms: B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, BRAF1, RAFB1, p94, v-Raf murine sarcoma viral oncogene homolog B1
Molecular Weight 87 kDa
Gene ID 673
Pathways MAPK Signaling, RTK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-BRAF Antibody Target Details BRAF Handling References for anti-BRAF Antibody (ABIN1105489) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-BRAF Antibody Target Details BRAF Application Details References for anti-BRAF Antibody (ABIN1105489) Images back to top
Format Liquid

References for anti-BRAF Antibody (ABIN1105489)

Product Details anti-BRAF Antibody Target Details BRAF Application Details Handling Images back to top
Background publications

Riesco-Eizaguirre, Gutiérrez-Martínez, García-Cabezas, Nistal, Santisteban: "The oncogene BRAF V600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I- targeting to the membrane." in: Endocrine-related cancer, Vol. 13, Issue 1, pp. 257-69, 2006

Sherrill, Kyte: "Activation of epidermal growth factor receptor by epidermal growth factor." in: Biochemistry, Vol. 35, Issue 18, pp. 5705-18, 1996

Images

Product Details anti-BRAF Antibody Target Details BRAF Application Details Handling References for anti-BRAF Antibody (ABIN1105489) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-BRAF antibody (V-Raf Murine Sarcoma Viral Oncogene Homolog B1) (ABIN1105489) anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody
Immunofluorescence (IF) image for anti-BRAF antibody (V-Raf Murine Sarcoma Viral Oncogene Homolog B1) (ABIN1105489) anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (Image 2)
Western Blotting (WB) image for anti-BRAF antibody (V-Raf Murine Sarcoma Viral Oncogene Homolog B1) (ABIN1105489) anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) antibody (Image 3)